Product image of Ibuprofen Sainsbury’s Bell, Sons & Co (Druggists) (Ibuprofen) supplied by GNH India

Ibuprofen Sainsbury’s Bell, Sons & Co (Druggists)

Active Ingredient:
Ibuprofen
Origin:
EU

Ibuprofen Sainsbury’s Bell, Sons & Co (Druggists) (Ibuprofen)

Ibuprofen, the active ingredient in Ibuprofen Sainsbury’s Bell, Sons & Co (Druggists), is a nonsteroidal anti-inflammatory drug (NSAID) presented as an oral tablet for oral use. It provides relief from mild to moderate pain, fever, and inflammation in adults and children as appropriate.

GNH India supplies Ibuprofen Sainsbury’s Bell, Sons & Co (Druggists) as a licensed, GDP-compliant international pharmaceutical supplier serving pharmacies and clinics worldwide.

Manufacturer / TM Owner

Bell Sons & Co (Druggists) Ltd

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Indications & Clinical Uses

Ibuprofen acts systemically to reduce pain, fever and inflammation associated with a variety of common conditions.

  • Mild to moderate pain: alleviates headache, dental, musculoskeletal and menstrual discomfort.
  • Fever: lowers elevated body temperature caused by infection or inflammatory processes.
  • Inflammation: reduces swelling and stiffness in conditions such as arthritis or soft‑tissue injury.

How It Works

  • Ibuprofen reversibly inhibits cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes, decreasing the conversion of arachidonic acid to prostaglandins. Lower prostaglandin levels diminish peripheral sensitisation of nociceptors, reduce fever‑inducing hypothalamic signals, and limit inflammatory exudate formation, thereby providing analgesic, antipyretic, and anti‑inflammatory effects.

Side Effects

Adverse reactions may range from mild, transient symptoms to serious, potentially life‑threatening conditions.

Common Side Effects

  • Gastrointestinal upset: nausea, dyspepsia or abdominal discomfort.
  • Headache: mild to moderate intensity.
  • Dizziness or vertigo.
  • Skin rash or mild itching.
  • Elevated blood pressure in susceptible individuals.

Serious or Rare Side Effects

  • Gastrointestinal bleeding, ulceration or perforation.
  • Acute renal impairment or failure.
  • Severe hypersensitivity reactions, including anaphylaxis.
  • Stevens‑Johnson syndrome or toxic epidermal necrolysis.
  • Hepatotoxicity presenting as jaundice or abnormal liver enzymes.

Precautions & Warnings

Before using ibuprofen, consider the following safety measures.

  • Assess gastrointestinal risk: avoid in patients with active ulcers or a history of GI bleeding.
  • Use the lowest effective dose for the shortest duration needed.
  • Avoid in individuals with known hypersensitivity to ibuprofen or other NSAIDs.
  • Exercise caution in patients with renal, hepatic or cardiovascular disease.
  • Monitor concomitant use of anticoagulants or antiplatelet agents.
  • Store at room temperature: keep in the original pack, protect from moisture and direct sunlight.

Avoid Interactions

Ibuprofen can affect the efficacy and safety of several other medicines.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of serious bleeding.
  • Other NSAIDs or aspirin: additive gastrointestinal toxicity.
  • Corticosteroids: heightened risk of ulceration and bleeding.
  • Lithium: ibuprofen may raise lithium serum levels.
  • Methotrexate: reduced clearance leading to toxicity.

Moderate Interactions (Monitor Closely)

  • Diuretics: possible reduction in renal function.
  • Antihypertensives (ACE inhibitors, ARBs): may blunt blood‑pressure‑lowering effect.
  • Selective serotonin reuptake inhibitors (SSRIs): increased bleeding tendency.
  • Beta‑blockers: potential for reduced renal perfusion.
  • Alcohol: synergistic gastrointestinal irritation.

Frequently Asked Questions

Ibuprofen Sainsbury’s Bell is an over‑the‑counter NSAID indicated for the temporary relief of mild to moderate pain, reduction of fever, and mitigation of inflammation associated with conditions such as headaches, dental pain, musculoskeletal aches, menstrual cramps, and arthritic flare‑ups.

Ibuprofen blocks the activity of cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which are essential for the synthesis of prostaglandins. By lowering prostaglandin levels, it reduces the sensitisation of pain receptors, diminishes the hypothalamic response that raises body temperature, and curtails the inflammatory cascade.

The appropriate dose of Ibuprofen Sainsbury’s Bell is determined by a qualified healthcare professional based on the individual’s age, weight, medical history, and the specific condition being treated. Patients should follow the prescriber’s instructions and the product label.

Ibuprofen should be used with caution during pregnancy, especially in the third trimester, as it may affect fetal cardiovascular development. It passes into breast milk in small amounts; therefore, breastfeeding mothers should consult a healthcare provider before use to weigh potential risks and benefits.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.

Ibuprofen and acetaminophen both relieve pain and fever, but ibuprofen also possesses anti‑inflammatory properties due to COX inhibition. Acetaminophen lacks significant anti‑inflammatory activity and has a different safety profile, being gentler on the stomach but potentially more hepatotoxic at high doses.

Ibuprofen Sainsbury’s Bell should be stored at room temperature, below 25 °C, in its original packaging to protect it from moisture and direct sunlight. Keep the container tightly closed and out of reach of children.

The product is taken orally, usually with a full glass of water. It can be taken with or without food; however, taking it with food or milk may reduce the likelihood of gastrointestinal discomfort.

Serious risks include gastrointestinal bleeding or ulceration, severe allergic reactions such as anaphylaxis, acute kidney injury, and cardiovascular events like heart attack or stroke, especially with high‑dose or prolonged use. Patients should seek immediate medical attention if they experience symptoms such as black stools, severe abdominal pain, swelling, or difficulty breathing.

Individuals with a known hypersensitivity to ibuprofen or other NSAIDs, active peptic ulcer disease, uncontrolled hypertension, severe heart failure, or significant renal or hepatic impairment should avoid ibuprofen unless directed by a physician. It is also contraindicated in the third trimester of pregnancy.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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