Product image of Ibuprofeno Pediátrico B. Braun (Ibuprofen) supplied by GNH India

Ibuprofeno Pediátrico B. Braun

Active Ingredient:
Ibuprofen
Origin:
EU

Ibuprofeno Pediátrico B. Braun (Ibuprofen)

Ibuprofen, the active ingredient in Ibuprofeno Pediátrico B. Braun, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an intravenous solution for intravenous use. It treats pain, fever, and inflammation in pediatric patients.

GNH India supplies Ibuprofeno Pediátrico B. Braun as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, clinics and health‑care institutions worldwide, ensuring quality‑assured delivery and regulatory compliance. The company manages global logistics, provides documentation for import clearance, and offers technical support for safe handling of the product through.

Manufacturer / TM Owner

B.Braun Melsungen Ag

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Indications & Clinical Uses

Ibuprofen, an NSAID, provides analgesic, antipyretic, and anti‑inflammatory effects by inhibiting prostaglandin synthesis.

  • Pain: reduces mild to moderate pain in children
  • Fever: lowers elevated body temperature in pediatric patients
  • Inflammation: decreases swelling associated with inflammatory conditions in children
  • Post‑operative discomfort: alleviates pain after surgical procedures
  • Musculoskeletal injury: helps control pain and inflammation from sprains or strains

How It Works

  • Ibuprofen exerts its effect by non‑selectively inhibiting the cyclo‑oxygenase enzymes COX‑1 and COX‑2. This blockade reduces the conversion of arachidonic acid to prostaglandins, which are mediators of pain, fever and inflammation. The decreased prostaglandin levels lower the sensitivity of nociceptors, reset the hypothalamic temperature set‑point, and limit inflammatory vascular responses.

Side Effects

Adverse reactions to intravenous ibuprofen may vary in frequency and severity.

Common Side Effects

  • Nausea: feeling of queasiness that may lead to vomiting
  • Vomiting: expulsion of stomach contents
  • Abdominal discomfort: mild stomach pain or cramps
  • Headache: mild to moderate pain in the head

Serious or Rare Side Effects

  • Gastrointestinal bleeding or ulceration: serious bleeding in the stomach or intestines
  • Acute kidney injury: sudden loss of kidney function
  • Severe allergic reactions such as anaphylaxis: rapid, life‑threatening hypersensitivity
  • Elevated liver enzymes or hepatic dysfunction: signs of liver stress or damage

Precautions & Warnings

When using intravenous ibuprofen in pediatric patients, several safety considerations should be observed.

  • Renal function: adjust dose or avoid use in children with impaired kidney function
  • Hepatic function: use with caution in patients with liver disease
  • Gastrointestinal risk: monitor for signs of bleeding, especially in those with ulcer history
  • Hypersensitivity: do not administer to children with known allergy to ibuprofen or other NSAIDs
  • Pediatric supervision: ensure dosing and administration are performed under qualified medical supervision
  • Store at ambient temperature: keep in original container, protect from moisture and light

Avoid Interactions

Ibuprofen may interact with other medicines, altering its efficacy or safety profile.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of bleeding
  • Other NSAIDs or aspirin: additive gastrointestinal toxicity
  • Corticosteroids: heightened chance of ulcer formation

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: possible reduction in renal function when combined
  • Lithium: ibuprofen can raise lithium serum concentrations

Frequently Asked Questions

Ibuprofeno Pediátrico B. Braun is an intravenous formulation of ibuprofen indicated for the relief of mild to moderate pain, reduction of fever, and control of inflammation in pediatric patients. It is commonly used in hospital settings for postoperative pain, febrile illnesses, and inflammatory conditions where rapid onset of action is desired.

Ibuprofen works by non‑selectively inhibiting the cyclo‑oxygenase enzymes COX‑1 and COX‑2. This inhibition blocks the conversion of arachidonic acid into prostaglandins, which are key mediators of pain, fever, and inflammation. Lower prostaglandin levels reduce the sensitivity of pain receptors, lower the hypothalamic set‑point for temperature, and diminish inflammatory swelling.

The appropriate dose of Ibuprofeno Pediátrico B. Braun is determined by the prescribing clinician based on the child’s age, weight, clinical condition, and renal or hepatic function. The healthcare professional calculates the exact milligram amount and infusion rate to achieve the desired therapeutic effect while minimizing risk.

Safety of intravenous ibuprofen during pregnancy or lactation has not been fully established, and the product is generally avoided unless the potential benefit outweighs the risk. Clinicians should evaluate each case individually, and alternative therapies may be preferred for pregnant or nursing mothers.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

The primary alternative to intravenous ibuprofen is intravenous acetaminophen, which provides antipyretic and analgesic effects but has minimal anti‑inflammatory activity. Ibuprofen offers stronger anti‑inflammatory action and may be preferred when inflammation is a major component, while acetaminophen is often chosen for patients at higher risk of gastrointestinal or renal side effects.

Store the intravenous solution at ambient temperature, preferably below 25 °C. Keep the vial in its original packaging, protect it from moisture and direct sunlight, and avoid freezing. Follow any additional handling instructions provided on the label to maintain product stability.

Ibuprofeno Pediátrico B. Braun is administered by slow intravenous infusion under the supervision of qualified medical staff. The infusion rate and total volume are calculated by the prescriber based on the child’s weight and clinical need, and the medication is given through a sterile IV line using aseptic technique.

Serious risks include gastrointestinal bleeding or ulceration, acute kidney injury, severe allergic reactions such as anaphylaxis, and hepatic dysfunction. Clinicians should monitor for signs of bleeding, changes in urine output, rash or breathing difficulty, and abnormal liver function tests, especially in high‑risk patients.

Children with known hypersensitivity to ibuprofen, other NSAIDs, or any component of the formulation should not receive this product. It is also contraindicated in patients with active gastrointestinal bleeding, severe renal impairment, or severe hepatic disease, and should be used with caution in those with a history of asthma triggered by NSAIDs.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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