Product image of Nurofen Comprimés Fondants (Ibuprofen) supplied by GNH India

Nurofen Comprimés Fondants

Active Ingredient:
Ibuprofen
Origin:
EU

Nurofen Comprimés Fondants (Ibuprofen)

Ibuprofen, the active ingredient in Nurofen Comprimés Fondants, is a non‑steroidal anti‑inflammatory drug (NSAID) presented as a melt‑in‑the‑mouth tablet for oral use. It treats mild to moderate pain, fever and inflammation in adults and children as appropriate.

GNH India supplies Nurofen Comprimés Fondants as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Reckitt Benckiser Healthcare (Belgium) Sa/Nv

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Indications & Clinical Uses

Ibuprofen acts systemically to reduce pain, fever and inflammation by inhibiting prostaglandin synthesis.

  • Headache: provides relief from tension‑type or migraine‑related pain.
  • Fever: lowers elevated body temperature.
  • Musculoskeletal pain: alleviates pain and swelling from sprains, strains, arthritis or other joint conditions.

How It Works

  • Ibuprofen reversibly inhibits cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes, decreasing the conversion of arachidonic acid to prostaglandins. Reduced prostaglandin levels diminish inflammation, lower the hypothalamic set‑point for temperature, and blunt nociceptive signaling, producing analgesic, antipyretic and anti‑inflammatory effects.

Side Effects

Common Side Effects

  • Gastrointestinal discomfort: nausea, dyspepsia, or abdominal pain.
  • Headache: mild transient headache.
  • Dizziness: feeling light‑headed or unsteady.
  • Skin rash: mild irritation or erythema.

Serious or Rare Side Effects

  • Severe gastrointestinal bleeding: black stools or vomiting blood.
  • Allergic reactions: swelling of face, lips, tongue or airway.
  • Liver injury: jaundice, elevated liver enzymes.
  • Kidney impairment: reduced urine output or peripheral edema.

Precautions & Warnings

Before using ibuprofen, consider the following safety measures.

  • Medical history: disclose ulcers, bleeding disorders, heart disease, or kidney disease.
  • Concomitant medications: avoid use with anticoagulants, other NSAIDs, or corticosteroids.
  • Pregnancy and lactation: consult a healthcare professional before use.
  • Alcohol consumption: limit intake as it may increase gastrointestinal risk.
  • Age considerations: use lower doses in elderly patients due to renal function changes.
  • Store at ambient temperature: keep in the original pack, protect from moisture and heat.

Avoid Interactions

Ibuprofen may interact with several medicines; monitoring is advised.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of bleeding.
  • Other NSAIDs (e.g., diclofenac): heightened gastrointestinal toxicity.
  • Selective serotonin reuptake inhibitors (SSRIs): elevated bleeding potential.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors (e.g., enalapril): may reduce renal function.
  • Diuretics (e.g., furosemide): possible renal impairment when combined.

Frequently Asked Questions

Nurofen Comprimés Fondants contains ibuprofen, an NSAID that is commonly used to relieve mild to moderate pain, reduce fever, and lessen inflammation caused by conditions such as headaches, musculoskeletal injuries, and arthritic disorders.

Ibuprofen works by reversibly inhibiting the cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which reduces the synthesis of prostaglandins. Lower prostaglandin levels diminish inflammation, lower the hypothalamic set‑point for temperature, and decrease the transmission of pain signals.

The appropriate dose of Nurofen Comprimés Fondants is determined by a prescriber based on the patient’s age, weight, clinical condition, and other medications. Patients should follow the specific instructions provided by their healthcare professional.

Safety of ibuprofen in pregnancy or while breastfeeding depends on the trimester and individual risk factors. It is generally advised to avoid ibuprofen during the third trimester and to consult a healthcare professional before use during any stage of pregnancy or lactation.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Ibuprofen and acetaminophen both relieve pain and fever, but ibuprofen also possesses anti‑inflammatory properties due to COX inhibition. Acetaminophen lacks significant anti‑inflammatory activity and has a different safety profile, especially regarding gastrointestinal and renal effects.

Store the melt‑in‑the‑mouth tablets at ambient temperature, preferably below 25 °C. Keep them in the original packaging, protect from moisture and direct sunlight, and ensure they are out of reach of children.

The tablets are designed to dissolve on the tongue without water. The patient should place the tablet in the mouth and allow it to melt completely before swallowing any residual material.

Serious risks include gastrointestinal bleeding, ulceration, severe allergic reactions such as anaphylaxis, and potential kidney or liver injury. Patients with pre‑existing cardiovascular, renal, or gastrointestinal disease should be monitored closely.

Individuals with known hypersensitivity to ibuprofen or other NSAIDs, active gastrointestinal bleeding or ulcer disease, severe heart failure, uncontrolled hypertension, or those in the third trimester of pregnancy should avoid ibuprofen unless directed by a healthcare professional.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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