Product image of Ibuprofen Abece (Ibuprofen) supplied by GNH India

Ibuprofen Abece

Active Ingredient:
Ibuprofen
Origin:
EU

Ibuprofen Abece (Ibuprofen)

Ibuprofen, the active ingredient in Ibuprofen Abece, is a nonsteroidal anti-inflammatory drug (NSAID) presented as a tablet for oral use. It treats mild to moderate pain, fever, and inflammatory joint conditions in adults and children when appropriate.
GNH India supplies Ibuprofen Abece as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Evolan Pharma Ab

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Indications & Clinical Uses

  • Ibuprofen acts as an analgesic and anti‑inflammatory agent across several common conditions.
  • Mild to moderate pain: provides relief from headaches, dental pain, musculoskeletal aches, and menstrual cramps.
  • Fever: lowers elevated body temperature associated with infections or inflammatory states.
  • Osteoarthritis: reduces joint pain and improves mobility in degenerative joint disease.
  • Rheumatoid arthritis: helps control inflammation and pain during disease flares.

How It Works

  • Ibuprofen non‑selectively inhibits cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes, decreasing the conversion of arachidonic acid to prostaglandins. Reduced prostaglandin synthesis diminishes peripheral sensitisation of nociceptors, lowers fever set‑point in the hypothalamus, and limits inflammatory mediators in tissues, resulting in analgesic, antipyretic, and anti‑inflammatory effects.

Side Effects

Adverse reactions may range from mild, transient symptoms to rare but serious events.

Common Side Effects

  • Gastrointestinal discomfort: nausea, dyspepsia, or abdominal pain.
  • Headache: mild to moderate intensity.
  • Dizziness or vertigo.
  • Skin rash: mild erythema or itching.

Serious or Rare Side Effects

  • Severe gastrointestinal bleeding or ulceration.
  • Anaphylactic or severe allergic reactions.
  • Elevated liver enzymes or hepatitis.
  • Acute kidney injury or reduced renal function.

Precautions & Warnings

Before using Ibuprofen, consider the following safety measures.

  • Assess renal function: avoid in patients with severe renal impairment.
  • Monitor gastrointestinal risk: use with food or a proton‑pump inhibitor if ulcer history exists.
  • Avoid in known hypersensitivity to ibuprofen or other NSAIDs.
  • Use cautiously in cardiovascular disease: may increase thrombotic risk.
  • Pregnancy and lactation: consult a healthcare professional before use.
  • Store at room temperature: keep in the original pack, protect from moisture and heat.

Avoid Interactions

Ibuprofen can interact with several drug classes, requiring attention to avoid adverse outcomes.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): heightened bleeding risk.
  • Selective COX‑2 inhibitors: additive renal toxicity.
  • Lithium: increased serum lithium concentrations.
  • Methotrexate: reduced clearance leading to toxicity.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: possible decline in renal function.
  • Diuretics: risk of volume depletion and renal impairment.
  • SSRIs or other serotonergic agents: increased bleeding tendency.

Frequently Asked Questions

Ibuprofen Abece is used to relieve mild to moderate pain such as headaches, dental pain, and musculoskeletal aches, to reduce fever, and to manage inflammatory joint conditions like osteoarthritis and rheumatoid arthritis. It provides analgesic, antipyretic, and anti‑inflammatory effects as part of standard therapeutic practice.

Ibuprofen works by non‑selectively blocking the cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which are essential for converting arachidonic acid into prostaglandins. By lowering prostaglandin levels, it reduces pain signalling, lowers fever, and diminishes inflammation in affected tissues.

The appropriate dose of Ibuprofen Abece is determined by the prescribing healthcare professional based on the patient’s age, weight, condition being treated, and overall health status. Dosage instructions are provided on the prescription label and should be followed exactly as directed.

Safety of ibuprofen during pregnancy and lactation depends on the trimester and individual risk factors. Generally, ibuprofen is avoided in the third trimester and used only when clearly needed in earlier stages. Breastfeeding mothers should consult a healthcare provider before use to assess potential exposure to the infant.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

Ibuprofen shares a similar mechanism with other non‑selective NSAIDs such as naproxen and diclofenac, offering comparable analgesic and anti‑inflammatory benefits. Differences lie in pharmacokinetic profiles, dosing frequency, and individual tolerability. Clinicians select the most appropriate NSAID based on patient comorbidities, risk of gastrointestinal or cardiovascular events, and convenience of dosing.

Ibuprofen Abece should be stored at room temperature, preferably below 25 °C. Keep the tablets in their original packaging, protect them from moisture, direct sunlight, and excessive heat to maintain product stability throughout its shelf life.

Ibuprofen Abece is taken orally, usually with a full glass of water. It can be taken with or without food, although taking it with meals may reduce gastrointestinal discomfort. The exact administration schedule is set by the prescriber.

Serious risks include gastrointestinal bleeding or ulceration, severe allergic reactions such as anaphylaxis, acute kidney injury, and cardiovascular events like heart attack or stroke, especially with high‑dose or prolonged use. Patients should be monitored for these events and seek immediate medical attention if they occur.

Individuals with known hypersensitivity to ibuprofen or any NSAID, those with active gastrointestinal bleeding, severe renal or hepatic impairment, and patients in the third trimester of pregnancy should avoid using Ibuprofen Abece. Consultation with a healthcare professional is essential for anyone with underlying health conditions.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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