Product image of Ibuprofen Abz (Ibuprofen) supplied by GNH India

Ibuprofen Abz

Active Ingredient:
Ibuprofen
Origin:
EU

Ibuprofen Abz (Ibuprofen)

Ibuprofen, the active ingredient in Ibuprofen Abz, is a non‑steroidal anti‑inflammatory drug presented as an oral formulation for oral use. It treats mild to moderate pain, fever, inflammation, osteoarthritis, rheumatoid arthritis and dysmenorrhea in adults.

GNH India supplies Ibuprofen Abz as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Abz-Pharma Gmbh

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Indications & Clinical Uses

Ibuprofen acts on inflammatory pathways to relieve pain and reduce fever.

  • Mild to moderate pain: provides analgesic relief for headaches, dental pain, musculoskeletal aches.
  • Fever: lowers elevated body temperature associated with infection or inflammation.
  • Inflammation: reduces swelling in conditions such as sprains or soft‑tissue injuries.
  • Osteoarthritis: alleviates joint pain and improves functional mobility.
  • Rheumatoid arthritis: helps control chronic joint inflammation and discomfort.
  • Dysmenorrhea: eases menstrual cramps and associated pelvic pain.

How It Works

  • Ibuprofen inhibits cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes, decreasing the conversion of arachidonic acid to prostaglandins. Reduced prostaglandin synthesis diminishes inflammation, pain signaling, and fever generation, providing symptomatic relief in a variety of acute and chronic conditions.

Side Effects

Adverse reactions may vary in frequency and severity.

Common Side Effects

  • Gastrointestinal discomfort: nausea, dyspepsia or abdominal pain.
  • Headache: mild to moderate intensity.
  • Dizziness: transient sensation of light‑headedness.
  • Skin rash: mild erythematous eruptions.

Serious or Rare Side Effects

  • Gastrointestinal bleeding or ulcer perforation.
  • Acute renal impairment, especially in volume‑depleted patients.
  • Severe allergic reactions such as anaphylaxis or Stevens‑Johnson syndrome.
  • Hepatic enzyme elevation indicating liver stress.
  • Cardiovascular events including hypertension or thrombotic episodes.

Precautions & Warnings

Before using ibuprofen, consider the following safety measures.

  • Assess renal function: avoid or adjust use in patients with significant kidney disease.
  • Monitor gastrointestinal risk: contraindicated in active peptic ulcer disease or recent GI bleeding.
  • Avoid concurrent anticoagulants: increased risk of bleeding when combined with warfarin or similar agents.
  • Use caution in asthma: may precipitate bronchospasm in susceptible individuals.
  • Store at room temperature: keep in the original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Ibuprofen can interact with several medicines; some require avoidance while others need close monitoring.

Major Interactions (Avoid)

  • Warfarin: potentiates anticoagulant effect, raising bleeding risk.
  • Other NSAIDs or aspirin: additive gastrointestinal toxicity.
  • Systemic corticosteroids: increase risk of ulceration and bleeding.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: may reduce antihypertensive efficacy and affect renal function.
  • Diuretics: concurrent use can impair renal perfusion, especially in the elderly.

Frequently Asked Questions

Ibuprofen Abz is an oral NSAID indicated for the relief of mild to moderate pain, reduction of fever, and management of inflammation associated with conditions such as osteoarthritis, rheumatoid arthritis, and dysmenorrhea. It is commonly prescribed when a non‑opioid analgesic and antipyretic are required.

Ibuprofen works by inhibiting the cyclooxygenase enzymes COX‑1 and COX‑2, which are essential for the synthesis of prostaglandins. By reducing prostaglandin production, ibuprofen decreases inflammation, alleviates pain signals, and lowers fever, providing symptomatic relief across a range of conditions.

The appropriate dose of ibuprofen is determined by the prescribing clinician based on the patient’s age, weight, clinical condition, and response to therapy. Dosage may vary from low‑dose regimens for occasional pain to higher, scheduled doses for chronic inflammatory disorders.

Ibuprofen is generally avoided during the third trimester of pregnancy because of potential fetal cardiovascular effects. In early pregnancy and while breastfeeding, it should only be used if clearly needed and after consultation with a healthcare professional, as safety data are limited.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Ibuprofen shares a similar mechanism of COX inhibition with other NSAIDs but is often preferred for its relatively short half‑life, predictable dosing, and wide therapeutic index. Compared with agents such as naproxen or diclofenac, ibuprofen may have a lower risk of prolonged gastrointestinal exposure but still requires caution in high‑risk patients.

Store Ibuprofen Abz at room temperature, preferably below 25 °C. Keep the product in its original container, protect it from moisture and direct sunlight, and ensure that it is out of reach of children. Do not use if the packaging is damaged or the tablets appear discolored.

Ibuprofen Abz is taken orally with a full glass of water. It may be taken with or without food; however, taking it with meals can reduce the likelihood of gastrointestinal discomfort. Swallow tablets whole; do not crush or chew unless specifically instructed by a healthcare provider.

Serious risks include gastrointestinal bleeding or ulcer perforation, acute kidney injury, severe allergic reactions such as anaphylaxis, and cardiovascular events like hypertension or thrombotic episodes. Patients should seek immediate medical attention if they experience black stools, sudden kidney dysfunction, severe rash, or chest pain.

Ibuprofen should be avoided in individuals with known hypersensitivity to ibuprofen or other NSAIDs, active peptic ulcer disease, severe heart failure, uncontrolled hypertension, or significant renal or hepatic impairment. It is also contraindicated in the third trimester of pregnancy and in patients taking certain anticoagulants without medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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