Product image of Ibuprofen Accord (Ibuprofen) supplied by GNH India

Ibuprofen Accord

Active Ingredient:
Ibuprofen
Origin:
EU

Ibuprofen Accord (Ibuprofen)

Ibuprofen, the active ingredient in Ibuprofen Accord, is a nonsteroidal anti-inflammatory drug presented as an oral tablet for oral use. It treats pain, fever and inflammation in adults and children when appropriate.

GNH India supplies Ibuprofen Accord as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Accord Healthcare B.V.

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Indications & Clinical Uses

Ibuprofen is a nonsteroidal anti-inflammatory drug that reduces prostaglandin‑mediated pain, fever, and inflammation.

  • Pain relief: alleviates mild to moderate pain such as headache, dental pain, and musculoskeletal discomfort.
  • Fever reduction: lowers elevated body temperature in febrile conditions.
  • Inflammation: decreases swelling associated with conditions like arthritis.

How It Works

  • Ibuprofen inhibits both cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes, blocking the conversion of arachidonic acid to prostaglandins. This reduction in prostaglandin synthesis diminishes inflammation, lowers fever, and decreases the perception of pain at peripheral and central sites.

Side Effects

Adverse reactions may vary in frequency and severity.

Common Side Effects

  • Stomach upset or dyspepsia
  • Nausea
  • Dizziness
  • Headache

Serious or Rare Side Effects

  • Gastrointestinal bleeding or ulcer perforation
  • Severe allergic reaction (anaphylaxis)
  • Kidney impairment or reduced renal function

Precautions & Warnings

Use ibuprofen with careful consideration of patient‑specific risk factors.

  • Assess renal function: adjust or avoid use in patients with significant kidney disease.
  • Evaluate gastrointestinal risk: avoid in individuals with active ulcers or a history of GI bleeding.
  • Use caution in cardiovascular disease: consider increased risk of thrombotic events.
  • Avoid concurrent use with other NSAIDs or anticoagulants: heightened bleeding risk.
  • Store at room temperature: keep in the original pack, protect from moisture and heat.

Avoid Interactions

Ibuprofen can interact with several medicines; monitoring is essential.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased bleeding risk.
  • Other NSAIDs: additive gastrointestinal toxicity.
  • Corticosteroids: heightened risk of ulceration.

Moderate Interactions (Monitor Closely):\n- Diuretics: possible reduction in renal clearance.

  • Lithium: increased lithium serum levels.
  • Methotrexate: reduced clearance leading to toxicity.

Frequently Asked Questions

Ibuprofen Accord contains ibuprofen, a nonsteroidal anti‑inflammatory drug that is commonly used to relieve mild to moderate pain, reduce fever, and lessen inflammation associated with conditions such as headache, dental pain, musculoskeletal aches, and arthritis.

Ibuprofen works by inhibiting the cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which are essential for the production of prostaglandins. Lower prostaglandin levels lead to reduced inflammation, decreased pain signaling, and a lower set point for body temperature.

The appropriate dose of Ibuprofen Accord is determined by a qualified prescriber based on the patient’s age, weight, clinical condition, and response to therapy. Dosage instructions should always follow the healthcare professional’s recommendation.

Safety of ibuprofen during pregnancy and lactation depends on the trimester and individual risk factors. Generally, ibuprofen is avoided in the third trimester and used only if clearly needed earlier in pregnancy. Breastfeeding mothers should consult their physician before use.

To place an order, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Ibuprofen is one of the most widely used NSAIDs and offers a balance of analgesic, antipyretic, and anti‑inflammatory effects with a relatively favorable safety profile when used at recommended doses. Compared with stronger NSAIDs like diclofenac, ibuprofen generally has lower cardiovascular risk but may be less potent for severe inflammatory conditions.

Ibuprofen Accord should be stored at room temperature, below 25 °C, in its original packaging to protect it from moisture and excessive heat. Keep the product out of reach of children and avoid exposure to direct sunlight.

Ibuprofen Accord is taken orally, usually with a full glass of water. It can be taken with or without food, although taking it with food may reduce the likelihood of stomach upset. Follow the prescriber’s instructions regarding timing and frequency.

Serious risks include gastrointestinal bleeding or ulcer perforation, severe allergic reactions such as anaphylaxis, and kidney impairment, especially in patients with pre‑existing renal disease or dehydration. Cardiovascular events like heart attack or stroke may also occur, particularly with high‑dose or long‑term use.

Ibuprofen should be avoided in individuals with known hypersensitivity to ibuprofen or other NSAIDs, active gastrointestinal ulcers, severe heart failure, uncontrolled hypertension, or those taking anticoagulants without medical supervision. Patients with significant renal or hepatic impairment should also consult a healthcare professional before use.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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