Product image of Ibuprofen Accord (Ibuprofen) supplied by GNH India

Ibuprofen Accord

Active Ingredient:
Ibuprofen
Origin:
EU

Ibuprofen Accord (Ibuprofen)

Ibuprofen, the active ingredient in Ibuprofen Accord, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an oral tablet for oral use. It relieves mild to moderate pain, reduces fever, and diminishes inflammation, and is commonly employed in osteoarthritis, rheumatoid arthritis, and dysmenorrhea.

GNH India supplies Ibuprofen Accord as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides reliable logistics for global distribution. Clients benefit from consistent product availability and regulatory compliance across EU and international markets.

Manufacturer / TM Owner

Accord Healthcare B.V.

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Indications & Clinical Uses

Ibuprofen is an NSAID that reduces inflammation and pain by inhibiting cyclooxygenase enzymes.

  • Mild to moderate pain: provides analgesia for headaches, dental pain, and musculoskeletal aches.
  • Fever: lowers elevated body temperature in acute febrile states.
  • Osteoarthritis: alleviates joint pain and improves function.
  • Rheumatoid arthritis: reduces joint inflammation and discomfort.
  • Dysmenorrhea: eases menstrual cramps and associated pain.

How It Works

  • Ibuprofen reversibly inhibits both cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes, decreasing the conversion of arachidonic acid to prostaglandins. The reduction in prostaglandin synthesis leads to diminished inflammation, lower pain signaling, and a decrease in fever response.

Side Effects

Adverse reactions may vary in frequency and severity.

Common Side Effects

  • Gastrointestinal discomfort: nausea, dyspepsia, or abdominal pain.
  • Headache: mild to moderate intensity.
  • Dizziness: transient light‑headedness.
  • Skin rash: mild erythema or itching.

Serious or Rare Side Effects

  • Gastrointestinal bleeding or ulcer perforation.
  • Acute kidney injury or reduced renal function.
  • Severe allergic reaction: anaphylaxis, angioedema, or Stevens‑Johnson syndrome.

Precautions & Warnings

Before using Ibuprofen Accord, consider the following safety measures.

  • Assess renal function: evaluate kidney health prior to initiation.
  • Monitor gastrointestinal risk: avoid in patients with active ulcers or recent GI bleeding.
  • Use lowest effective dose: limit exposure to reduce adverse events.
  • Avoid concurrent NSAIDs: combined use increases toxicity risk.
  • Store at ambient temperature: keep below 25°C in the original packaging, protect from moisture.

Avoid Interactions

Ibuprofen can interact with several medicines; awareness helps prevent complications.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased bleeding risk.
  • Selective serotonin reuptake inhibitors (SSRIs): heightened gastrointestinal bleeding.
  • Lithium: increased serum lithium concentrations.
  • Methotrexate: reduced clearance leading to toxicity.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: possible reduction in renal function.
  • Diuretics: risk of renal impairment and electrolyte imbalance.
  • Corticosteroids: additive gastrointestinal ulcer risk.

Frequently Asked Questions

Ibuprofen Accord is indicated for the relief of mild to moderate pain, reduction of fever, and mitigation of inflammation. It is commonly prescribed for conditions such as osteoarthritis, rheumatoid arthritis, dysmenorrhea, and other inflammatory or painful disorders where an NSAID is appropriate.

Ibuprofen works by reversibly inhibiting the cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which are essential for converting arachidonic acid into prostaglandins. By lowering prostaglandin production, it reduces the inflammatory response, diminishes pain signaling, and helps lower elevated body temperature.

The specific dose of Ibuprofen Accord is determined by the prescribing healthcare professional based on the individual’s condition, age, weight, and response to therapy. Typical adult dosing ranges are established in clinical guidelines, but the exact regimen should always follow the prescriber’s instructions.

Safety of ibuprofen during pregnancy and lactation depends on the trimester and clinical circumstances. It is generally avoided in the third trimester because of potential fetal cardiovascular effects, and caution is advised earlier in pregnancy. Breastfeeding mothers should consult a healthcare provider, as ibuprofen does pass into breast milk in small amounts.

To place an order, submit an enquiry on the Ibuprofen Accord product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

Ibuprofen shares the core mechanism of COX inhibition with other NSAIDs, offering a balance of analgesic, antipyretic, and anti‑inflammatory effects. Compared with agents like naproxen, ibuprofen has a shorter half‑life, which may allow more flexible dosing but may also require more frequent administration for sustained relief.

Ibuprofen Accord should be stored at ambient temperature, preferably below 25 °C. Keep the product in its original packaging to protect it from moisture and light. Do not store in areas with high humidity or extreme heat, and keep it out of reach of children.

Ibuprofen Accord is taken orally, usually with a full glass of water. It can be taken with or without food; however, taking it with food or milk may reduce the likelihood of gastrointestinal discomfort. Swallow tablets whole; do not crush or chew unless specifically instructed by a healthcare professional.

Serious risks include gastrointestinal bleeding or ulcer perforation, acute kidney injury, and severe allergic reactions such as anaphylaxis or Stevens‑Johnson syndrome. Patients should be alert for signs of black or tarry stools, sudden loss of kidney function, swelling, rash, or difficulty breathing and seek medical attention promptly.

Ibuprofen Accord should be avoided in individuals with a known hypersensitivity to ibuprofen or other NSAIDs, active gastrointestinal ulcers or bleeding, severe renal impairment, uncontrolled heart failure, and in the third trimester of pregnancy. Anyone with a history of cardiovascular disease should discuss risks with their physician before use.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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