Product image of Ibuprofen Accord (Ibuprofen) supplied by GNH India

Ibuprofen Accord

Active Ingredient:
Ibuprofen
Origin:
EU

Ibuprofen Accord (Ibuprofen)

Ibuprofen, the active ingredient in Ibuprofen Accord, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an oral dosage form for oral use. It treats mild to moderate pain, fever, and inflammatory conditions such as arthritis in adults and children as appropriate.

GNH India supplies Ibuprofen Accord as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Accord Healthcare B.V.

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Indications & Clinical Uses

Ibuprofen is an NSAID that reduces inflammation and pain by inhibiting prostaglandin synthesis.

  • Mild to moderate pain: provides relief from headaches, dental pain, and musculoskeletal discomfort.
  • Fever: lowers elevated body temperature.
  • Inflammatory conditions such as arthritis: decreases joint swelling and improves mobility.

How It Works

  • Ibuprofen exerts its effect through reversible inhibition of cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes. This blockade reduces the conversion of arachidonic acid to prostaglandins, leading to decreased inflammation, analgesia, and antipyresis at sites of tissue injury or infection.

Side Effects

Adverse reactions may occur with ibuprofen use and vary in frequency and severity.

Common Side Effects

  • Upset stomach
  • Nausea
  • Headache

Serious or Rare Side Effects

  • Gastrointestinal bleeding or ulceration
  • Severe allergic reaction (e.g., anaphylaxis, Stevens‑Johnson syndrome)
  • Kidney impairment or failure

Precautions & Warnings

When using ibuprofen, consider the following safety measures.

  • Assess gastrointestinal risk: avoid in patients with active ulcers or a history of serious GI bleeding.
  • Monitor renal function: use cautiously in individuals with kidney disease or dehydration.
  • Avoid concurrent anticoagulants: increased risk of bleeding when combined with warfarin, heparin, or similar agents.
  • Use the lowest effective dose: limit duration to the shortest period necessary to achieve therapeutic benefit.
  • Store at ambient temperature: keep in the original pack, protect from moisture and heat.

Avoid Interactions

Ibuprofen can interact with other medicines, altering efficacy or safety.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): heightened bleeding risk.
  • Other NSAIDs or aspirin: additive gastrointestinal toxicity.
  • Selective serotonin reuptake inhibitors (SSRIs): increased potential for bleeding.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: may reduce renal function when used together.
  • Diuretics: combined use can impair kidney function.
  • Lithium: ibuprofen may raise serum lithium concentrations.

Frequently Asked Questions

Ibuprofen Accord contains ibuprofen, an NSAID indicated for relief of mild to moderate pain such as headaches, dental pain, and musculoskeletal aches; for reduction of fever; and for management of inflammatory conditions like osteoarthritis and rheumatoid arthritis.

Ibuprofen works by reversibly inhibiting the cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which reduces the synthesis of prostaglandins. Lower prostaglandin levels diminish inflammation, pain signaling, and fever generation at the site of tissue injury.

The specific dose and dosing interval are determined by the prescribing healthcare professional based on the patient’s age, weight, condition being treated, and overall health status. Prescribers follow local guidelines to select an appropriate regimen.

Ibuprofen should be used with caution during pregnancy, especially in the third trimester, and only if clearly needed. It passes into breast milk in small amounts; nursing mothers should consult their clinician before use to weigh benefits against potential risks.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Compared with acetaminophen, ibuprofen provides both analgesic and anti‑inflammatory effects, making it useful for conditions involving inflammation. Compared with other NSAIDs, its safety profile is similar, though individual agents differ in gastrointestinal and cardiovascular risk, so choice depends on patient‑specific factors.

Store the product at ambient temperature, preferably below 25 °C. Keep it in the original packaging to protect from moisture and direct sunlight. Do not use if the container is damaged or the tablets appear discolored.

Ibuprofen Accord is taken orally with a full glass of water. It may be taken with food or milk to lessen stomach irritation, but it can also be taken on an empty stomach if tolerated. Swallow tablets whole; do not crush or chew unless directed by a healthcare professional.

Serious risks include gastrointestinal bleeding or ulceration, severe allergic reactions such as anaphylaxis or Stevens‑Johnson syndrome, kidney injury especially in dehydrated or renal‑impaired patients, and increased cardiovascular events like heart attack or stroke when used long‑term or at high doses.

Individuals with a known allergy to ibuprofen or other NSAIDs, active gastrointestinal ulcers, severe kidney or liver disease, uncontrolled hypertension, or those in the third trimester of pregnancy should avoid ibuprofen. Consultation with a healthcare provider is essential before starting therapy.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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