Product image of Ibuprofen Accord Healthcare (Ibuprofen) supplied by GNH India

Ibuprofen Accord Healthcare

Active Ingredient:
Ibuprofen
Origin:
EU

Ibuprofen Accord Healthcare (Ibuprofen)

Ibuprofen, the active ingredient in Ibuprofen Accord Healthcare, is a nonsteroidal anti-inflammatory drug (NSAID) presented as a oral tablet for oral use. It treats mild to moderate pain, fever and inflammation in adults and children as appropriate.

GNH India supplies Ibuprofen Accord Healthcare as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Accord Healthcare Limited

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Indications & Clinical Uses

Ibuprofen acts on inflammatory pathways to relieve pain and reduce fever.

  • Mild to moderate pain: provides analgesic relief for headaches, dental pain, musculoskeletal discomfort.
  • Fever: lowers elevated body temperature associated with infections or inflammatory conditions.
  • Inflammatory arthritis (osteoarthritis, rheumatoid arthritis): reduces joint inflammation and improves mobility.

How It Works

  • Ibuprofen exerts its effect by non‑selectively inhibiting cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes, which blocks the conversion of arachidonic acid to prostaglandins. The reduced prostaglandin synthesis diminishes peripheral sensitisation of nociceptors, lowers the hypothalamic set‑point for temperature, and curtails inflammatory exudate formation.

Side Effects

Adverse reactions may occur with ibuprofen use and vary in frequency.

Common Side Effects

  • Gastrointestinal discomfort or dyspepsia
  • Nausea or vomiting
  • Headache
  • Dizziness
  • Mild skin rash
  • Elevated blood pressure

Serious or Rare Side Effects

  • Gastrointestinal bleeding or ulcer perforation
  • Acute renal failure or worsening of chronic kidney disease
  • Severe hypersensitivity reactions including anaphylaxis
  • Stevens‑Johnson syndrome or toxic epidermal necrolysis
  • Cardiovascular thrombotic events such as myocardial infarction or stroke
  • Hepatotoxicity in susceptible individuals

Precautions & Warnings

Before using ibuprofen, consider the following safety measures.

  • Assess renal function: avoid or adjust dose in severe renal impairment.
  • Monitor gastrointestinal risk: use with food or a gastro‑protective agent in high‑risk patients.
  • Avoid in known hypersensitivity to NSAIDs or aspirin.
  • Use cautiously in cardiovascular disease: may increase thrombotic risk.
  • Pregnancy and lactation: consult a healthcare professional before use.
  • Store at ambient temperature: keep in the original pack, protect from moisture.

Avoid Interactions

Ibuprofen can interact with other medicines; some combinations should be avoided while others require monitoring.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin, DOACs): increased risk of bleeding.
  • Selective serotonin reuptake inhibitors (SSRIs): heightened gastrointestinal bleeding risk.
  • ACE inhibitors or diuretics: may impair renal function, especially in volume‑depleted patients.

Moderate Interactions (Monitor Closely)

  • Other NSAIDs: additive gastrointestinal toxicity.
  • Corticosteroids: increased risk of ulceration and bleeding.

Frequently Asked Questions

Ibuprofen Accord Healthcare is used to relieve mild to moderate pain such as headaches, dental discomfort, and musculoskeletal aches; to lower fever associated with infections or inflammatory states; and to reduce inflammation in conditions like osteoarthritis and rheumatoid arthritis.

Ibuprofen works by non‑selectively blocking the cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which reduces the production of prostaglandins. Lower prostaglandin levels diminish peripheral nerve sensitisation, lower the hypothalamic temperature set‑point, and limit inflammatory fluid accumulation, resulting in analgesic, antipyretic, and anti‑inflammatory effects.

The appropriate dose of Ibuprofen Accord Healthcare is determined by the prescribing healthcare professional based on the patient’s age, weight, clinical condition, and response to therapy. Patients should follow the prescriber’s instructions and the product label for dosing details.

Safety of ibuprofen during pregnancy and lactation depends on the trimester and individual risk factors. Generally, ibuprofen is avoided in the third trimester because of potential fetal cardiovascular effects, and it should be used only if clearly needed during earlier stages. Breastfeeding mothers should consult a healthcare provider before use.

To order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.

Ibuprofen and naproxen belong to the same NSAID class and share similar mechanisms of COX inhibition. Ibuprofen generally has a shorter half‑life, requiring more frequent dosing, while naproxen provides longer duration of action. Both carry comparable gastrointestinal and cardiovascular risks, but individual patient factors guide the choice between them.

Ibuprofen Accord Healthcare should be stored at ambient temperature, preferably below 25 °C. Keep the tablets in the original packaging to protect them from moisture and light, and store them out of reach of children.

The product is taken orally, usually with a full glass of water. It can be taken with or without food, although taking it with food or milk may reduce gastrointestinal discomfort. The exact administration schedule should follow the prescriber’s directions.

Serious risks include gastrointestinal bleeding or ulcer perforation, acute kidney injury, severe allergic reactions such as anaphylaxis, and increased risk of cardiovascular events like heart attack or stroke, especially with high‑dose or prolonged use. Patients should seek immediate medical attention if they experience signs of these conditions.

Ibuprofen should be avoided by individuals with known hypersensitivity to ibuprofen or other NSAIDs, those with active gastrointestinal ulceration or bleeding, patients with severe renal impairment, and anyone in the third trimester of pregnancy unless specifically advised by a healthcare professional.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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