Product image of Ibuprofen Adgc (Ibuprofen) supplied by GNH India

Ibuprofen Adgc

Active Ingredient:
Ibuprofen
Origin:
EU

Ibuprofen Adgc (Ibuprofen)

Ibuprofen, the active ingredient in Ibuprofen Adgc, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an oral tablet (strength unspecified) for oral use. It treats mild to moderate pain, fever and inflammation in adults and children as directed by a healthcare professional.

GNH India supplies Ibuprofen Adgc as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Zentiva Pharma Gmbh

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Indications & Clinical Uses

Ibuprofen acts as an anti‑inflammatory and analgesic, addressing conditions within the musculoskeletal and febrile disease families.

  • Mild to moderate pain: provides relief by reducing pain signals.
  • Fever: lowers elevated body temperature through prostaglandin inhibition.
  • Inflammation: diminishes swelling in injured tissues.
  • Osteoarthritis: eases joint discomfort and improves mobility.
  • Rheumatoid arthritis: helps control chronic joint inflammation.
  • Dysmenorrhea: reduces menstrual cramp pain.

How It Works

  • Ibuprofen reversibly inhibits cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes, decreasing the conversion of arachidonic acid to prostaglandins. The reduced prostaglandin synthesis leads to lowered inflammation, pain perception, and fever response, providing symptomatic relief in affected tissues.

Side Effects

Ibuprofen may cause a range of adverse reactions, varying from mild to severe.

Common Side Effects

  • Gastrointestinal discomfort: nausea, dyspepsia or heartburn.
  • Headache: mild to moderate intensity.
  • Dizziness: transient sensation of light‑headedness.
  • Rash: mild skin irritation or itching.
  • Elevated blood pressure: modest increase in some patients.

Serious or Rare Side Effects

  • Gastrointestinal bleeding or ulceration.
  • Severe allergic reactions: angioedema, bronchospasm or anaphylaxis.
  • Renal impairment: reduced kidney function or acute failure.
  • Hepatotoxicity: abnormal liver enzymes or hepatitis.
  • Cardiovascular events: increased risk of myocardial infarction or stroke.

Precautions & Warnings

When using ibuprofen, consider the following safety measures to minimize risk.

  • Assess renal function: avoid use in severe kidney disease.
  • Monitor cardiovascular status: use cautiously in patients with heart disease.
  • Evaluate gastrointestinal risk: avoid in active ulcers or severe GI bleeding.
  • Review concomitant medications: check for other NSAIDs or anticoagulants.
  • Pregnancy and lactation: discuss with a healthcare provider before use.
  • Store at ambient temperature: keep in the original container, protect from moisture and heat.

Avoid Interactions

Ibuprofen can affect the activity of several other medicines; awareness of these interactions helps ensure safe co‑administration.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased bleeding risk.
  • High‑dose aspirin: heightened gastrointestinal toxicity.
  • Selective COX‑2 inhibitors: additive renal and cardiovascular effects.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: possible reduction in antihypertensive efficacy.
  • Diuretics: potential for decreased renal perfusion.
  • Lithium: risk of elevated serum lithium levels.

Frequently Asked Questions

Ibuprofen Adgc is an oral NSAID indicated for the relief of mild to moderate pain, reduction of fever, and management of inflammation associated with conditions such as osteoarthritis, rheumatoid arthritis, and dysmenorrhea. It works by targeting the underlying inflammatory pathways that cause these symptoms.

Ibuprofen works by reversibly inhibiting the cyclooxygenase‑1 and cyclo‑oxygenase‑2 enzymes, which are essential for converting arachidonic acid into prostaglandins. Lower prostaglandin levels reduce inflammation, diminish pain signaling, and lower body temperature during fever.

The appropriate dose of Ibuprofen Adgc is determined by the prescribing healthcare professional based on the patient’s age, weight, clinical condition, and response to therapy. Patients should follow the prescriber’s instructions and not exceed the recommended amount.

Safety of ibuprofen during pregnancy and lactation depends on the trimester and individual risk factors. It is generally avoided in the third trimester and used only if clearly needed in earlier stages. Breastfeeding mothers should consult a healthcare provider before use.

To order Ibuprofen Adgc, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Ibuprofen shares a similar mechanism with other non‑selective NSAIDs such as naproxen and diclofenac, offering comparable analgesic and antipyretic effects. Compared with selective COX‑2 inhibitors, ibuprofen has a broader COX inhibition profile, which may increase gastrointestinal risk but carries a lower cardiovascular risk in many patients.

Ibuprofen Adgc should be stored at ambient temperature, below 25 °C, in its original packaging to protect it from moisture and direct sunlight. Keep the product out of reach of children and avoid storing it in bathrooms or near heat sources.

Ibuprofen Adgc is taken orally with a full glass of water. It may be taken with or without food; however, taking it with food can reduce the likelihood of gastrointestinal discomfort. Swallow tablets whole; do not crush or chew them unless instructed otherwise.

Serious risks include gastrointestinal bleeding or ulceration, severe allergic reactions such as anaphylaxis, renal impairment, hepatotoxicity, and an increased risk of cardiovascular events like myocardial infarction or stroke, especially with long‑term or high‑dose use.

Individuals with a known hypersensitivity to ibuprofen or other NSAIDs, active gastrointestinal ulcers, severe renal or hepatic impairment, uncontrolled hypertension, or those in the third trimester of pregnancy should avoid using Ibuprofen Adgc unless specifically directed by a healthcare professional.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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