Product image of Ibuprofen Akut Abz (Ibuprofen) supplied by GNH India

Ibuprofen Akut Abz

Active Ingredient:
Ibuprofen
Origin:
EU

Ibuprofen Akut Abz (Ibuprofen)

Ibuprofen, the active ingredient in Ibuprofen Akut Abz, is a non‑steroidal anti‑inflammatory drug presented as an oral formulation for oral use. It treats mild to moderate pain, fever and inflammatory conditions such as arthritis in adults and children as appropriate.

GNH India supplies Ibuprofen Akut Abz as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Abz-Pharma Gmbh

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Indications & Clinical Uses

Ibuprofen is an NSAID that reduces inflammation and pain by inhibiting cyclooxygenase enzymes.

  • Mild to moderate pain: provides analgesic relief for headaches, dental pain, musculoskeletal discomfort.
  • Fever: lowers elevated body temperature associated with infections or other causes.
  • Inflammatory conditions such as arthritis: decreases joint swelling and improves mobility.

How It Works

  • Ibuprofen exerts its effect by non‑selectively inhibiting cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes, which blocks the conversion of arachidonic acid to prostaglandins. Reduced prostaglandin synthesis diminishes inflammation, lowers pain signaling, and resets the hypothalamic set‑point for body temperature, resulting in analgesic, antipyretic, and anti‑inflammatory actions.

Side Effects

Adverse reactions may vary in frequency and severity.

Common Side Effects

  • Gastrointestinal discomfort: nausea, dyspepsia, or abdominal pain.
  • Headache: mild to moderate intensity.
  • Dizziness or vertigo.
  • Skin rash or mild itching.

Serious or Rare Side Effects

  • Gastrointestinal bleeding or ulcer perforation.
  • Acute renal impairment or failure.
  • Severe hypersensitivity reactions, including anaphylaxis.
  • Hepatic injury or elevated liver enzymes.
  • Cardiovascular events such as myocardial infarction or stroke.
  • Blood dyscrasias, including thrombocytopenia.

Precautions & Warnings

Use ibuprofen with attention to patient‑specific risk factors and proper storage.

  • Assess renal function: avoid in patients with severe kidney disease.
  • Monitor gastrointestinal risk: consider gastro‑protective agents in those with ulcer history.
  • Avoid concurrent anticoagulants: increased bleeding risk.
  • Use caution in cardiovascular disease: NSAIDs may raise blood pressure.
  • Store at ambient temperature: keep in the original pack, protect from moisture and heat.

Avoid Interactions

Ibuprofen can interact with several drug classes, requiring vigilance.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin, heparin): heightened bleeding risk.
  • Other NSAIDs or COX‑2 inhibitors: additive gastrointestinal toxicity.
  • Lithium therapy: increased lithium serum concentrations.
  • Methotrexate: reduced clearance leading to toxicity.

Moderate Interactions (Monitor Closely)

  • Corticosteroids: increased ulcer risk.
  • Diuretics (especially thiazides): may reduce renal perfusion.
  • ACE inhibitors or ARBs: potential impairment of renal function.

Frequently Asked Questions

Ibuprofen Akut Abz contains ibuprofen, an NSAID indicated for the relief of mild to moderate pain, reduction of fever, and management of inflammatory conditions such as osteoarthritis and rheumatoid arthritis. It is commonly prescribed when a non‑opioid analgesic and antipyretic are needed.

Ibuprofen works by non‑selectively inhibiting the cyclooxygenase enzymes COX‑1 and COX‑2, which reduces the synthesis of prostaglandins. Lower prostaglandin levels diminish inflammation, decrease pain‑signal transmission, and reset the hypothalamic temperature set‑point, thereby providing analgesic, antipyretic, and anti‑inflammatory effects.

The appropriate dose of Ibuprofen Akut Abz is determined by the prescribing healthcare professional based on the patient’s age, weight, clinical condition, and response to therapy. Dosage recommendations follow national guidelines and should be individualized for each patient.

Ibuprofen should be used during pregnancy only if clearly needed and prescribed by a qualified clinician, as it may affect fetal cardiovascular development, especially in the third trimester. While limited data exist for breastfeeding, ibuprofen is excreted in small amounts in milk; a prescriber should weigh benefits against potential risks.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any required temperature control) and assistance with import documentation.

Ibuprofen shares a similar mechanism of COX inhibition with other non‑selective NSAIDs such as naproxen and diclofenac. Compared with some alternatives, ibuprofen has a relatively short half‑life, which may allow flexible dosing but may also require more frequent administration for sustained effect. Safety profiles are comparable, with gastrointestinal and renal considerations common to the class.

Ibuprofen Akut Abz should be stored at ambient temperature, below 25 °C, in its original packaging to protect it from moisture and direct sunlight. Keep the product out of reach of children and avoid storing it in bathrooms or other humid environments.

Ibuprofen Akut Abz is intended for oral administration. The tablets (or other oral dosage form) should be swallowed whole with a full glass of water, preferably with food or milk to lessen gastrointestinal irritation, unless otherwise directed by a healthcare professional.

Serious risks include gastrointestinal bleeding or ulceration, acute kidney injury, severe allergic reactions such as anaphylaxis, and increased cardiovascular events like myocardial infarction or stroke, particularly with high‑dose or prolonged use. Patients should be monitored for signs of these complications and seek immediate medical attention if they occur.

Ibuprofen Akut Abz is contraindicated in individuals with known hypersensitivity to ibuprofen or other NSAIDs, active gastrointestinal ulceration, severe heart failure, or significant renal impairment. It should also be avoided in patients who have had a recent coronary artery bypass graft surgery or who are taking certain anticoagulants without medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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