Product image of Ibuprofen Akut Holsten (Ibuprofen) supplied by GNH India

Ibuprofen Akut Holsten

Active Ingredient:
Ibuprofen
Origin:
EU

Ibuprofen Akut Holsten (Ibuprofen)

Ibuprofen, the active ingredient in Ibuprofen Akut Holsten, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an oral formulation for oral use. It treats mild to moderate pain, fever and inflammation in adults and children.

GNH India supplies Ibuprofen Akut Holsten as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company follows stringent quality standards and offers reliable logistics for global distribution.

Manufacturer / TM Owner

Holsten Pharma Gmbh

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Indications & Clinical Uses

Ibuprofen is an NSAID that reduces pain, fever and inflammation by inhibiting prostaglandin synthesis.

  • Headache: provides relief of pain and reduces associated discomfort.
  • Dental pain: alleviates postoperative or acute tooth pain.
  • Musculoskeletal pain: reduces pain and swelling in muscles and joints.
  • Fever: lowers elevated body temperature.
  • Dysmenorrhea: eases menstrual cramps.

How It Works

  • Ibuprofen reversibly inhibits cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes, decreasing the conversion of arachidonic acid to prostaglandins. The reduced prostaglandin levels diminish peripheral sensitisation of nociceptors, lower the hypothalamic set‑point for temperature, and limit inflammatory exudate formation, resulting in analgesic, antipyretic and anti‑inflammatory effects.

Side Effects

Adverse reactions may range from mild to severe and should be monitored during therapy.

Common Side Effects

  • Gastrointestinal upset: nausea, dyspepsia or abdominal discomfort.
  • Headache: transient mild headache.
  • Dizziness: occasional light‑headedness.
  • Rash: mild skin irritation or erythema.

Serious or Rare Side Effects

  • Gastrointestinal bleeding or ulcer perforation.
  • Acute renal impairment, especially in volume‑depleted patients.
  • Severe allergic reactions such as anaphylaxis.
  • Hepatic enzyme elevation or hepatitis.
  • Stevens‑Johnson syndrome or toxic epidermal necrolysis.

Precautions & Warnings

Before initiating therapy, consider the following safety measures.

  • Assess gastrointestinal risk: evaluate history of ulcers, bleeding or chronic NSAID use.
  • Monitor renal function: avoid or adjust dose in patients with severe kidney disease.
  • Avoid in known hypersensitivity: discontinue if rash, swelling or breathing difficulty occurs.
  • Use lowest effective dose: limit duration to the shortest period needed for symptom control.
  • Store at ambient temperature: keep in the original pack, protect from moisture and heat.

Avoid Interactions

Ibuprofen can interact with several drug classes; awareness helps prevent adverse outcomes.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of bleeding.
  • Other NSAIDs or aspirin: additive gastrointestinal toxicity.
  • Selective serotonin reuptake inhibitors (SSRIs): heightened bleeding tendency.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: may reduce renal perfusion and function.
  • Diuretics: combined use can impair kidney function.
  • Lithium: ibuprofen may raise lithium serum concentrations.

Frequently Asked Questions

Ibuprofen Akut Holsten is indicated for the relief of mild to moderate pain, reduction of fever, and management of inflammation. Common clinical situations include headache, dental pain, musculoskeletal aches, fever associated with infections, and menstrual cramps.

Ibuprofen blocks the cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which are essential for producing prostaglandins. By lowering prostaglandin levels, it reduces the sensitisation of pain receptors, lowers the hypothalamic set‑point for temperature, and diminishes inflammatory swelling.

The appropriate dose is determined by the prescribing healthcare professional based on the patient’s age, weight, clinical condition and response. Patients should follow the prescriber’s instructions and not exceed the recommended amount.

Safety in pregnancy and lactation depends on the trimester and individual risk assessment. Ibuprofen is generally avoided in the third trimester and used with caution earlier. Breastfeeding mothers should consult their physician, as small amounts may pass into milk.

Enquiries are submitted via the product page at gnhindia.com, where you specify the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Ibuprofen provides both analgesic and anti‑inflammatory effects, whereas acetaminophen mainly offers pain relief and fever reduction without significant anti‑inflammatory activity. Ibuprofen may be preferred when inflammation is a key component, but it carries a higher risk of gastrointestinal and renal side effects.

Store the product at ambient temperature, below 25 °C, in the original packaging. Keep it away from moisture, direct sunlight and excessive heat to maintain stability and potency.

The medication is taken orally, usually with a glass of water. It can be taken with or without food, although taking it with food may reduce gastrointestinal discomfort.

Serious risks include gastrointestinal bleeding or ulcer perforation, severe allergic reactions such as anaphylaxis, acute kidney injury, and rare skin disorders like Stevens‑Johnson syndrome. Patients should seek immediate medical attention if they experience symptoms such as vomiting blood, severe abdominal pain, rash or swelling.

Individuals with a known hypersensitivity to ibuprofen or other NSAIDs, those with active gastrointestinal ulcers, severe renal or hepatic impairment, and patients in the third trimester of pregnancy should not use this product unless specifically directed by a physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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