Product image of Ibuprofen Al (Ibuprofen) supplied by GNH India

Ibuprofen Al

Active Ingredient:
Ibuprofen
Origin:
EU

Ibuprofen Al (Ibuprofen)

Ibuprofen, the active ingredient in Ibuprofen Al, is a nonsteroidal anti-inflammatory drug presented as an oral tablet for oral use. It treats mild to moderate pain, fever and inflammation in adults and children as appropriate.

GNH India supplies Ibuprofen Al as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Aliud Pharma Gmbh

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Indications & Clinical Uses

Ibuprofen is a nonsteroidal anti-inflammatory drug that reduces inflammation and pain by inhibiting cyclooxygenase enzymes.

  • Mild to moderate pain: provides analgesia for headaches, dental pain, and musculoskeletal discomfort.
  • Fever: lowers elevated body temperature in febrile conditions.
  • Inflammation: alleviates swelling associated with arthritis and other inflammatory disorders.

How It Works

  • Ibuprofen inhibits both cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes, decreasing the conversion of arachidonic acid to prostaglandins. Reduced prostaglandin synthesis leads to diminished inflammation, pain signaling, and fever generation at peripheral and central sites.

Side Effects

Adverse reactions may range from mild gastrointestinal discomfort to serious systemic events.

Common Side Effects

  • Nausea: mild stomach upset after ingestion.
  • Dyspepsia: indigestion or heartburn.
  • Headache: transient cranial discomfort.
  • Dizziness: feeling light‑headed or unsteady.
  • Rash: mild skin irritation or redness.
  • Diarrhea: loose stools.

Serious or Rare Side Effects

  • Gastrointestinal bleeding: blood in stool or vomiting blood.
  • Peptic ulceration: painful sores in the stomach or duodenum.
  • Renal impairment: reduced kidney function or acute failure.
  • Severe allergic reaction: anaphylaxis with swelling, breathing difficulty.
  • Hepatic injury: elevated liver enzymes or jaundice.
  • Stevens‑Johnson syndrome: severe skin blistering and detachment.

Precautions & Warnings

Before using ibuprofen, consider the following safety measures.

  • Assess gastrointestinal risk: avoid in patients with active ulcers or bleeding disorders.
  • Monitor renal function: use caution in those with kidney disease or dehydration.
  • Avoid in known hypersensitivity: discontinue if allergic reactions occur.
  • Use lowest effective dose: limit duration to the shortest period needed.
  • Consider cardiovascular risk: patients with heart disease should consult a clinician.
  • Store at below 25°C: keep in the original pack, protect from moisture.

Avoid Interactions

Ibuprofen can interact with several medication classes; awareness helps prevent adverse outcomes.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of bleeding.
  • Other NSAIDs: additive gastrointestinal toxicity.
  • SSRIs (e.g., fluoxetine): heightened bleeding tendency.

Moderate Interactions (Monitor Closely)

  • Diuretics: may affect renal clearance and electrolyte balance.
  • Lithium: ibuprofen can raise lithium serum concentrations.
  • Methotrexate: reduced excretion may increase toxicity.

Frequently Asked Questions

Ibuprofen Al is used to relieve mild to moderate pain, reduce fever, and lessen inflammation. It is commonly employed for headaches, dental discomfort, musculoskeletal aches, febrile illnesses, and inflammatory conditions such as arthritis, providing symptomatic relief in both adult and pediatric patients as directed by a healthcare professional.

Ibuprofen works by blocking the activity of cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which are essential for producing prostaglandins. Prostaglandins amplify pain signals, promote inflammation, and raise body temperature. By reducing prostaglandin synthesis, ibuprofen diminishes pain perception, lowers fever, and curtails inflammatory swelling.

The specific dose of Ibuprofen Al is determined by the prescribing clinician based on the patient’s age, weight, condition being treated, and overall health status. Healthcare providers select the appropriate strength, frequency, and duration to achieve therapeutic effect while minimizing risk.

Safety of ibuprofen during pregnancy and lactation depends on the trimester and individual risk factors. Generally, ibuprofen is avoided in the third trimester because it may affect fetal circulation. During breastfeeding, small amounts pass into milk, and clinicians weigh benefits against potential risks before recommending use.

To place an order, visit the product page on gnhindia.com, enter the required quantity, and submit the enquiry form. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifying trade or institutional credentials before providing pricing, availability, shipping details, and any necessary import documentation.

Ibuprofen shares the core mechanism of COX inhibition with other NSAIDs such as naproxen and diclofenac, offering comparable analgesic and antipyretic effects. Differences lie in pharmacokinetic profiles, dosing intervals, and individual tolerability. Ibuprofen’s relatively short half‑life often requires multiple daily doses, whereas some alternatives may allow once‑daily dosing.

Ibuprofen Al should be stored at temperatures below 25 °C in a dry environment. Keep the product in its original packaging to protect it from moisture and light, and ensure the container is tightly closed when not in use.

Ibuprofen Al is administered orally, typically as a tablet that is swallowed whole with a full glass of water. It may be taken with or without food, although taking it with food can help reduce gastrointestinal discomfort.

Serious risks include gastrointestinal bleeding or ulceration, severe allergic reactions such as anaphylaxis, renal impairment, and cardiovascular events like heart attack or stroke, especially with high‑dose or prolonged use. Patients should seek immediate medical attention if they experience symptoms such as vomiting blood, severe abdominal pain, or sudden swelling.

Individuals with a known hypersensitivity to ibuprofen or any other NSAIDs, those with active gastrointestinal ulcers, severe heart failure, uncontrolled hypertension, or significant renal or hepatic impairment should avoid using Ibuprofen Al unless specifically directed by a physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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