Product image of Ibuprofen Altan (Ibuprofen) supplied by GNH India

Ibuprofen Altan

Active Ingredient:
Ibuprofen
Origin:
EU

Ibuprofen Altan (Ibuprofen)

Ibuprofen, the active ingredient in Ibuprofen Altan, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an intravenous solution for intravenous use. It treats pain, fever and inflammation in hospital settings, including postoperative and musculoskeletal pain.

GNH India supplies Ibuprofen Altan as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals worldwide.

Manufacturer / TM Owner

Altan Pharma Ltd

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Indications & Clinical Uses

  • Ibuprofen Altan, an NSAID administered intravenously, is used for conditions where rapid analgesic and antipyretic effects are needed.
  • Pain: provides rapid relief of moderate to severe pain
  • Fever: reduces elevated body temperature
  • Postoperative pain: controls pain after surgical procedures
  • Musculoskeletal pain: alleviates inflammation‑related discomfort
  • Inflammation: decreases swelling in acute inflammatory states

How It Works

  • Ibuprofen Altan exerts its effect by non‑selectively inhibiting cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which blocks the conversion of arachidonic acid to prostaglandins. The resulting reduction in prostaglandin synthesis diminishes peripheral sensitisation, lowers the hypothalamic set‑point for temperature, and limits inflammatory exudate formation, producing analgesic, antipyretic and anti‑inflammatory actions.

Side Effects

Adverse reactions may occur with any intravenous NSAID and should be monitored.

Common Side Effects

  • Nausea or upset stomach
  • Headache
  • Dizziness or light‑headedness
  • Pain or irritation at the injection site
  • Mild, transient increase in blood pressure
  • Temporary changes in renal function tests

Serious or Rare Side Effects

  • Gastrointestinal bleeding or ulceration
  • Severe allergic reactions including anaphylaxis
  • Stevens‑Johnson syndrome or toxic epidermal necrolysis
  • Acute renal failure
  • Cardiovascular thrombotic events such as myocardial infarction
  • Hepatic necrosis or severe liver injury

Precautions & Warnings

  • Before initiating therapy, clinicians should evaluate patient‑specific risk factors and monitor for complications.
  • Assess renal function: check baseline creatinine and monitor during treatment
  • Evaluate bleeding risk: avoid in active peptic ulcer disease or uncontrolled coagulopathy
  • Use caution in cardiovascular disease: monitor blood pressure and signs of thrombosis
  • Avoid in known hypersensitivity to ibuprofen or other NSAIDs
  • Limit use in pregnancy: safety not established, especially in the third trimester
  • Store at ambient temperature: keep in original container, protect from moisture and direct light

Avoid Interactions

Ibuprofen Altan can alter the activity of several concomitant medicines; careful assessment is required.

Major Interactions (Avoid)

  • Warfarin: increased risk of serious bleeding
  • ACE inhibitors: potential for reduced renal function
  • Lithium: elevated serum lithium concentrations

Moderate Interactions (Monitor Closely)

  • Diuretics: may exacerbate renal impairment
  • SSRIs: heightened bleeding tendency
  • Methotrexate: reduced clearance leading to toxicity

Frequently Asked Questions

Ibuprofen Altan is an intravenous formulation of ibuprofen used in hospital settings to provide rapid relief of moderate to severe pain, reduce fever, and control inflammation associated with postoperative procedures, musculoskeletal injuries, and acute inflammatory conditions.

Ibuprofen blocks the activity of cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, preventing the formation of prostaglandins that mediate pain, fever, and inflammation. By lowering prostaglandin levels, it reduces peripheral sensitisation, lowers the hypothalamic temperature set‑point, and limits inflammatory swelling.

The appropriate dose of Ibuprofen Altan is determined by the prescribing clinician based on the patient’s condition, weight, renal function and other clinical factors. Specific dosing regimens are not disclosed publicly and should follow the prescriber’s order.

Safety of intravenous ibuprofen during pregnancy has not been established, and it is generally avoided, especially in the third trimester. Breastfeeding mothers should consult their healthcare provider, as ibuprofen can be excreted in milk and may affect the infant.

To order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed) and required import documentation.

Ibuprofen Altan offers a well‑known safety profile and is often compared with IV ketorolac. While both provide potent analgesia, ibuprofen has a slightly longer half‑life and may be preferred when a broader anti‑inflammatory effect is desired, whereas ketorolac is typically limited to short‑term use because of higher renal and bleeding risk.

The product should be stored at ambient temperature, below 25 °C, in its original packaging. Protect it from moisture, direct sunlight and extreme temperatures. Once opened, use according to the manufacturer’s aseptic guidelines and discard any remaining solution after the recommended in‑use period.

Ibuprofen Altan is given by intravenous infusion. The solution is diluted in an appropriate compatible fluid and administered over the time period prescribed by the clinician, typically ranging from a few minutes to an hour, depending on the dose and patient tolerance.

Serious adverse events include gastrointestinal bleeding, severe allergic reactions such as anaphylaxis, Stevens‑Johnson syndrome, acute renal failure, cardiovascular thrombotic events (e.g., myocardial infarction or stroke) and hepatic necrosis. Immediate medical attention is required if any of these occur.

Patients with known hypersensitivity to ibuprofen or other NSAIDs, active gastrointestinal ulceration, uncontrolled bleeding disorders, severe renal or hepatic impairment, and those in the third trimester of pregnancy should avoid this medication. Use should also be cautious in patients with cardiovascular disease.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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