Product image of Ibuprofen Apteo Med (Ibuprofen) supplied by GNH India

Ibuprofen Apteo Med

Active Ingredient:
Ibuprofen
Origin:
EU

Ibuprofen Apteo Med (Ibuprofen)

Ibuprofen, the active ingredient in Ibuprofen Apteo Med, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an oral dosage form for oral use. It is used to relieve pain, reduce fever, and lessen inflammation in adults and children when appropriate.

GNH India supplies Ibuprofen Apteo Med as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Synoptis Pharma Sp Z O O

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Indications & Clinical Uses

Ibuprofen acts on the cyclo‑oxygenase pathway to manage several common conditions.

  • Pain: Provides analgesic relief for mild to moderate acute or chronic pain.
  • Fever: Lowers elevated body temperature associated with infectious or inflammatory processes.
  • Inflammation: Reduces swelling and redness in soft‑tissue injuries.
  • Osteoarthritis: Improves joint comfort and function in degenerative joint disease.
  • Rheumatoid arthritis: Helps control pain and inflammation during disease flares.

How It Works

  • Ibuprofen reversibly inhibits both cyclo‑oxygenase‑1 (COX‑1) and cyclo‑oxygenase‑2 (COX‑2) enzymes, decreasing the conversion of arachidonic acid to prostaglandins. The reduced prostaglandin synthesis diminishes peripheral sensitisation of nociceptors, lowers fever set‑points in the hypothalamus, and limits inflammatory exudate formation, resulting in analgesic, antipyretic, and anti‑inflammatory effects.

Side Effects

Adverse reactions may occur with ibuprofen use and are classified by frequency and severity.

Common Side Effects

  • Dyspepsia: mild stomach discomfort or heartburn.
  • Nausea: feeling of queasiness.
  • Headache: transient cranial pain.
  • Dizziness: occasional light‑headedness.
  • Rash: mild skin redness or itching.

Serious or Rare Side Effects

  • Gastrointestinal ulceration or bleeding.
  • Renal impairment or acute kidney injury.
  • Hepatotoxicity: elevated liver enzymes.
  • Severe hypersensitivity reactions, including anaphylaxis.
  • Cardiovascular events such as myocardial infarction or stroke.

Precautions & Warnings

Before using ibuprofen, consider the following safety measures.

  • Assess renal function: avoid use in severe kidney disease without medical supervision.
  • Evaluate cardiovascular risk: use cautiously in patients with hypertension or heart disease.
  • Review gastrointestinal history: avoid in active ulcer disease or recent GI bleeding.
  • Monitor liver enzymes: discontinue if significant hepatic dysfunction occurs.
  • Avoid concurrent use with other NSAIDs or anticoagulants unless directed by a clinician.
  • Store at ambient temperature: keep below 25 °C, retain in original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Ibuprofen can interact with several drug classes, requiring attention to avoid adverse outcomes.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of serious bleeding.
  • High‑dose aspirin: heightened gastrointestinal toxicity.
  • Selective COX‑2 inhibitors: additive renal and cardiovascular risk.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: possible reduction in antihypertensive effect and renal function.
  • Diuretics: may enhance renal impairment.
  • Lithium: ibuprofen can raise serum lithium levels.
  • Methotrexate: reduced clearance leading to toxicity.
  • SSRIs or SNRIs: elevated risk of GI bleeding.

Frequently Asked Questions

Ibuprofen Apteo Med is indicated for the relief of mild to moderate pain, reduction of fever, and control of inflammation. It is commonly employed in conditions such as osteoarthritis, rheumatoid arthritis, dental pain, musculoskeletal injuries, and febrile illnesses when prescribed by a qualified healthcare professional.

Ibuprofen works by reversibly blocking the cyclo‑oxygenase‑1 and cyclo‑oxygenase‑2 enzymes, which are essential for converting arachidonic acid into prostaglandins. By lowering prostaglandin production, ibuprofen reduces pain signalling, lowers fever, and diminishes inflammatory swelling at the site of injury or disease.

The appropriate dose of Ibuprofen Apteo Med is determined by the prescribing clinician based on the patient’s age, weight, medical condition, and response to therapy. Dosage instructions are provided on the prescription label and should be followed exactly as directed.

Ibuprofen should be used during pregnancy only if clearly needed and after consultation with a healthcare provider, as it may affect fetal cardiovascular development in the third trimester. It is generally considered compatible with breastfeeding, but mothers should discuss any concerns with their physician to weigh potential risks and benefits.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

Ibuprofen and naproxen belong to the same NSAID class and share similar mechanisms of COX inhibition. Ibuprofen generally has a shorter half‑life, requiring more frequent dosing, while naproxen offers longer duration of action. Choice between them depends on clinical factors, patient tolerance, and physician preference.

Ibuprofen Apteo Med should be stored at ambient temperature, preferably below 25 °C. Keep the product in its original container, protect it from moisture, heat, and direct sunlight, and ensure the packaging remains tightly closed until use.

Ibuprofen Apteo Med is taken orally, usually with a full glass of water. It may be taken with or without food, although taking it with food can help minimise gastrointestinal discomfort. The exact administration schedule is set by the prescribing clinician.

Serious risks include gastrointestinal bleeding or ulceration, renal impairment, hepatotoxicity, and increased cardiovascular events such as heart attack or stroke, especially with high‑dose or prolonged use. Patients should seek immediate medical attention if they experience severe abdominal pain, blood in stool, sudden kidney problems, or signs of an allergic reaction.

Individuals with a known hypersensitivity to ibuprofen or other NSAIDs, active gastrointestinal ulcers, severe heart failure, uncontrolled hypertension, or significant renal or hepatic impairment should avoid ibuprofen unless a physician determines that benefits outweigh risks. Pregnant women in the third trimester should also refrain from using ibuprofen.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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