Product image of Ibuprofen Aristo (Ibuprofen) supplied by GNH India

Ibuprofen Aristo

Active Ingredient:
Ibuprofen
Origin:
EU

Ibuprofen Aristo (Ibuprofen)

Ibuprofen, the active ingredient in Ibuprofen Aristo, is a Nonsteroidal anti-inflammatory drug (NSAID) presented as an oral dosage form for oral use. It treats mild to moderate pain, fever and inflammation in adults and children when appropriate.
GNH India supplies Ibuprofen Aristo as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Aristo Pharma Gmbh (Art 57)

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Indications & Clinical Uses

Ibuprofen is an NSAID that reduces pain, fever, and inflammation.

  • Mild to moderate pain: provides analgesic relief for headaches, dental pain, musculoskeletal discomfort, and menstrual cramps.
  • Fever: lowers elevated body temperature associated with infections or inflammatory conditions.
  • Inflammation: decreases swelling and stiffness in arthritis, soft‑tissue injuries, and other inflammatory disorders.

How It Works

  • Ibuprofen exerts its effect by non‑selectively inhibiting cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes, which blocks the conversion of arachidonic acid to prostaglandins. Reduced prostaglandin synthesis diminishes inflammation, pain signaling, and fever generation at the site of tissue injury or infection.

Side Effects

Adverse reactions may occur with ibuprofen use and are categorized by frequency and severity.

Common Side Effects

  • Gastrointestinal upset: nausea, dyspepsia, or mild abdominal pain.
  • Headache: transient headache episodes.
  • Dizziness or light‑headedness.
  • Mild skin rash or itching.
  • Elevated blood pressure in susceptible individuals.
  • Transient increase in liver enzymes.

Serious or Rare Side Effects

  • Gastrointestinal bleeding or ulcer perforation.
  • Severe allergic reactions such as anaphylaxis or angioedema.
  • Acute renal failure or worsening of chronic kidney disease.
  • Hepatotoxicity with marked liver enzyme elevation.
  • Cardiovascular events including myocardial infarction or stroke, especially with high‑dose or prolonged use.
  • Blood dyscrasias such as thrombocytopenia or leukopenia.

Precautions & Warnings

Before using Ibuprofen Aristo, consider the following safety measures.

  • Assess renal function: avoid or adjust use in severe renal impairment.
  • Monitor gastrointestinal risk: use with food or a gastro‑protective agent in high‑risk patients.
  • Avoid in known hypersensitivity to ibuprofen or other NSAIDs.
  • Use caution in cardiovascular disease: evaluate thrombotic risk.
  • Pregnancy and breastfeeding: consult a healthcare professional before use.
  • Store at room temperature: keep in the original pack, protect from moisture and heat.

Avoid Interactions

Ibuprofen may interact with other medicines; some combinations require avoidance while others need close monitoring.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of bleeding.
  • Other NSAIDs or aspirin: additive gastrointestinal toxicity.
  • Selective serotonin reuptake inhibitors (SSRIs): heightened bleeding tendency.
  • Corticosteroids: elevated ulcer risk.
  • ACE inhibitors or ARBs: potential reduction in renal function.

Moderate Interactions (Monitor Closely)

  • Diuretics: may impair kidney function when combined.
  • Lithium: ibuprofen can raise lithium serum levels.
  • Methotrexate: reduced clearance leading to toxicity.
  • Cyclosporine: increased risk of nephrotoxicity.
  • Blood pressure medications: monitor for changes in blood pressure.

Frequently Asked Questions

Ibuprofen Aristo is used to relieve mild to moderate pain such as headaches, dental discomfort, and musculoskeletal aches; to reduce fever associated with infections or inflammatory states; and to lessen inflammation and swelling in conditions like arthritis or soft‑tissue injuries.

Ibuprofen works by blocking the cyclooxygenase enzymes COX‑1 and COX‑2, which are needed to produce prostaglandins. Lower prostaglandin levels reduce inflammation, diminish pain signal transmission, and reset the body’s temperature‑regulating center, thereby lowering fever.

The appropriate dose of Ibuprofen Aristo is determined by the prescribing healthcare professional based on the patient’s age, weight, clinical condition, and any relevant medical history. Patients should follow the prescriber’s instructions and not exceed the recommended amount.

Safety of ibuprofen during pregnancy or lactation depends on the trimester and individual risk factors. It is generally avoided in the third trimester and used only if clearly needed earlier in pregnancy. Breastfeeding mothers should consult a healthcare provider before use.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Ibuprofen shares the same mechanism of COX inhibition as other NSAIDs such as naproxen or diclofenac, but it has a relatively short half‑life and is often preferred for short‑term pain or fever relief. Compared with aspirin, ibuprofen has a lower risk of gastrointestinal irritation at standard doses.

Ibuprofen Aristo should be stored at room temperature, below 25 °C, in its original packaging to protect it from moisture and direct sunlight. Keep the product out of reach of children and do not use it after the expiration date.

Ibuprofen Aristo is taken orally, usually with a full glass of water. It can be taken with or without food, although taking it with food may reduce the chance of stomach upset. The exact administration schedule is set by the prescriber.

Serious risks include gastrointestinal bleeding or ulcer perforation, severe allergic reactions such as anaphylaxis, acute kidney injury, liver toxicity, and increased risk of cardiovascular events like heart attack or stroke, particularly with high‑dose or long‑term therapy.

Individuals with known hypersensitivity to ibuprofen or other NSAIDs, those with active gastrointestinal bleeding, severe renal or hepatic impairment, uncontrolled hypertension, or certain cardiovascular conditions should avoid ibuprofen unless specifically directed by a healthcare professional.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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