Product image of Ibuprofen Aurobindo (Ibuprofen) supplied by GNH India

Ibuprofen Aurobindo

Active Ingredient:
Ibuprofen
Origin:
EU

Ibuprofen Aurobindo (Ibuprofen)

Ibuprofen, the active ingredient in Ibuprofen Aurobindo, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an oral dosage form for oral use. It treats pain, fever and inflammation in adults and children when prescribed by a healthcare professional.

GNH India supplies Ibuprofen Aurobindo as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Aurobindo Pharma B.V.

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Indications & Clinical Uses

  • Ibuprofen works by reducing inflammation and relieving symptoms in several common conditions.
  • Pain: Provides relief from mild to moderate pain such as headache, dental pain, or musculoskeletal discomfort.
  • Fever: Lowers elevated body temperature associated with infections or inflammatory states.
  • Inflammation: Decreases swelling and redness in conditions like sprains, strains, and soft‑tissue injuries.
  • Arthritis: Alleviates joint pain and stiffness in osteoarthritis and rheumatoid arthritis.

How It Works

  • Ibuprofen reversibly inhibits cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes, which blocks the conversion of arachidonic acid to prostaglandins. The reduction in prostaglandin synthesis diminishes inflammation, pain signaling, and fever generation at the site of tissue injury or infection.

Side Effects

Ibuprofen may cause a range of adverse reactions, from mild to serious.

Common Side Effects

  • Gastrointestinal discomfort such as nausea, dyspepsia or heartburn.
  • Mild headache or dizziness.
  • Transient elevation of liver enzymes.
  • Mild rash or itching.
  • Fluid retention leading to peripheral edema.

Serious or Rare Side Effects

  • Gastrointestinal ulceration or bleeding.
  • Severe hypersensitivity reactions including anaphylaxis.
  • Renal impairment or acute kidney injury.
  • Cardiovascular events such as myocardial infarction or stroke, especially with high‑dose or prolonged use.
  • Hepatotoxicity with marked liver enzyme elevation.

Precautions & Warnings

  • Before using Ibuprofen, consider the following safety measures.
  • Assess renal function: Avoid use in patients with severe kidney disease.
  • Evaluate cardiovascular risk: Use cautiously in individuals with heart disease or hypertension.
  • Monitor gastrointestinal health: Patients with a history of ulcers should use protective agents.
  • Avoid concurrent NSAIDs: Do not combine with other nonsteroidal anti‑inflammatory drugs.
  • Pregnancy and lactation: Discuss risks with a healthcare provider before use.
  • Store at ambient temperature: Keep below 25 °C in the original container, protected from moisture and direct sunlight.

Avoid Interactions

Ibuprofen can interact with several medicines, altering efficacy or safety.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): Increased risk of bleeding.
  • High‑dose aspirin: Enhanced gastrointestinal toxicity.
  • Selective COX‑2 inhibitors: Additive cardiovascular risk.
  • Lithium: Potential increase in lithium serum levels.
  • Methotrexate: Reduced renal clearance leading to toxicity.

Moderate Interactions (Monitor Closely):\n- ACE inhibitors or ARBs: May diminish antihypertensive effect and affect kidney function.

  • Diuretics: Possible reduction in diuretic efficacy and renal perfusion.
  • SSRIs or SNRIs: Heightened bleeding tendency.
  • Corticosteroids: Increased risk of gastrointestinal ulceration.

Frequently Asked Questions

Ibuprofen Aurobindo is a generic ibuprofen product indicated for the relief of mild to moderate pain, reduction of fever, and management of inflammation associated with conditions such as arthritis, musculoskeletal injuries, and common infections.

Ibuprofen works by reversibly inhibiting the cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which reduces the synthesis of prostaglandins. Lower prostaglandin levels decrease inflammation, pain signaling, and fever responses at the site of tissue injury or infection.

The appropriate dose of Ibuprofen Aurobindo is determined by a prescriber based on the patient’s age, weight, clinical condition, and response to therapy. Patients should follow the healthcare professional’s instructions and not exceed the recommended amount.

Safety of ibuprofen during pregnancy and lactation depends on the trimester and individual risk factors. It is generally avoided in the third trimester and used only if clearly needed in earlier stages. Breastfeeding mothers should consult a healthcare provider before use.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Ibuprofen shares the same class mechanism as other NSAIDs such as naproxen or diclofenac, but it has a relatively short half‑life and is often preferred for short‑term pain or fever. Compared with stronger NSAIDs, ibuprofen generally has a lower risk of cardiovascular events at standard doses.

Ibuprofen Aurobindo should be stored at ambient temperature, below 25 °C, in its original packaging to protect it from moisture and light. Keep the product out of reach of children and do not use if the packaging is damaged.

Ibuprofen Aurobindo is taken orally, usually with a full glass of water. It may be taken with food or milk to lessen gastrointestinal discomfort, but it can also be taken on an empty stomach if tolerated.

Serious risks include gastrointestinal bleeding or ulceration, severe allergic reactions such as anaphylaxis, renal impairment, and increased cardiovascular events like heart attack or stroke, particularly with high‑dose or prolonged therapy.

Individuals with known hypersensitivity to ibuprofen or other NSAIDs, active gastrointestinal ulcer disease, severe renal or hepatic impairment, uncontrolled hypertension, or those who have had a recent cardiovascular event should avoid using Ibuprofen Aurobindo unless directed by a physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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