Product image of Ibuprofen B. Braun (Ibuprofen) supplied by GNH India

Ibuprofen B. Braun

Active Ingredient:
Ibuprofen
Origin:
EU

Ibuprofen B. Braun (Ibuprofen)

Ibuprofen, the active ingredient in Ibuprofen B. Braun, is a nonsteroidal anti-inflammatory drug presented as an injectable solution for intravenous use. It provides analgesic, antipyretic and anti‑inflammatory effects, and is commonly employed to manage moderate to severe pain, postoperative discomfort, fever and acute inflammatory conditions in adult patients.

GNH India supplies Ibuprofen B. Braun as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, ensuring quality, regulatory compliance, and reliable delivery across global markets.

Manufacturer / TM Owner

B.Braun Melsungen Ag

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Indications & Clinical Uses

  • Ibuprofen is an NSAID that reduces inflammation and pain by inhibiting cyclooxygenase enzymes.
  • Pain: provides analgesia for moderate to severe acute pain.
  • Fever: lowers elevated body temperature.
  • Inflammation: diminishes swelling and inflammatory response.
  • Postoperative pain: controls pain after surgical procedures.

How It Works

  • Ibuprofen reversibly inhibits both COX‑1 and COX‑2 enzymes, decreasing the conversion of arachidonic acid to prostaglandins. The reduction in prostaglandin synthesis leads to lowered inflammation, pain signaling, and fever generation, producing its analgesic, antipyretic, and anti‑inflammatory actions throughout the body.

Side Effects

Adverse reactions may occur with intravenous ibuprofen administration.

Common Side Effects

  • Nausea or mild gastrointestinal upset.
  • Dizziness or light‑headedness.
  • Headache.
  • Injection‑site pain or erythema.
  • Transient increase in blood pressure.

Serious or Rare Side Effects

  • Anaphylactic or severe allergic reactions.
  • Gastrointestinal bleeding or ulceration.
  • Acute renal impairment or failure.
  • Cardiovascular thrombotic events (e.g., myocardial infarction, stroke).
  • Hepatic dysfunction or elevated liver enzymes.
  • Stevens‑Johnson syndrome or toxic epidermal necrolysis.

Precautions & Warnings

  • When using intravenous ibuprofen, clinicians should observe several safety measures.
  • Assess renal function: monitor patients with impaired kidney function.
  • Monitor for bleeding: avoid in patients with active ulcers or on anticoagulant therapy.
  • Avoid in known hypersensitivity: discontinue if an allergic reaction occurs.
  • Use caution in pregnancy: limited data, avoid in the third trimester.
  • Limit duration: employ the lowest effective dose for the shortest necessary period.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Ibuprofen can interact with several drug classes, requiring careful management.

Major Interactions (Avoid)

  • Other NSAIDs: increased risk of gastrointestinal bleeding.
  • Anticoagulants (warfarin, DOACs): heightened bleeding tendency.
  • SSRIs or other serotonergic agents: amplified bleeding risk.

Moderate Interactions (Monitor Closely)

  • Diuretics: may affect renal function and fluid balance.
  • Lithium: ibuprofen may raise serum lithium concentrations.

Frequently Asked Questions

Ibuprofen B. Braun is an intravenous formulation of ibuprofen used in hospital settings to provide rapid relief of moderate to severe pain, reduce fever, and control inflammation, including postoperative pain and acute inflammatory conditions.

Ibuprofen blocks the cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which are required for prostaglandin production. By lowering prostaglandin levels, it diminishes pain signaling, reduces fever, and suppresses inflammatory swelling.

The specific dose and infusion rate are determined by the prescribing clinician based on the patient’s condition, weight, renal function, and therapeutic goals. Healthcare professionals should follow local guidelines and product labeling.

Safety data for intravenous ibuprofen during pregnancy are limited. It is generally avoided in the third trimester because of potential fetal risks. Breastfeeding mothers should consult a physician, as ibuprofen can be excreted in milk.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed) and required import documentation.

Compared with other injectable NSAIDs such as ketorolac, ibuprofen offers a broader anti‑inflammatory profile and a slightly lower risk of renal toxicity at equivalent analgesic doses, but it may have a higher incidence of gastrointestinal upset. Choice depends on the clinical scenario and patient tolerance.

The product must be stored refrigerated between 2 °C and 8 °C, protected from light, and must not be frozen or shaken. Before use, inspect the vial for particulate matter and ensure the solution is at room temperature if required for infusion.

Ibuprofen B. Braun is given by intravenous infusion. The vial is typically diluted with compatible IV fluid according to the prescribing information, then infused over a specified period (often 15–30 minutes) under clinical supervision.

Serious risks include severe allergic reactions (anaphylaxis), gastrointestinal bleeding, acute kidney injury, cardiovascular events such as myocardial infarction or stroke, and rare skin reactions like Stevens‑Johnson syndrome. Prompt recognition and discontinuation are essential if these occur.

Contraindications include known hypersensitivity to ibuprofen or other NSAIDs, active gastrointestinal bleeding or ulcer disease, severe renal impairment, patients in the third trimester of pregnancy, and individuals receiving anticoagulant therapy with uncontrolled bleeding risk.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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