Product image of Ibuprofen B. Braun (Ibuprofen) supplied by GNH India

Ibuprofen B. Braun

Active Ingredient:
Ibuprofen
Origin:
EU

Ibuprofen B. Braun (Ibuprofen)

Ibuprofen, the active ingredient in Ibuprofen B. Braun, is a nonsteroidal anti‑inflammatory drug (NSAID) presented as an injectable solution for intravenous use. It treats pain, fever, inflammation and post‑operative discomfort in hospitalized patients.

GNH India supplies Ibuprofen B. Braun as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals worldwide.

Manufacturer / TM Owner

B.Braun Melsungen Ag

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Indications & Clinical Uses

Ibuprofen B. Braun is an NSAID used to manage conditions that involve pain, fever or inflammation.

  • Pain: Provides analgesic relief for acute and moderate pain conditions.
  • Fever: Reduces elevated body temperature associated with infectious or inflammatory states.
  • Inflammation: Decreases swelling and tissue inflammation in musculoskeletal disorders.
  • Post‑operative pain: Controls postoperative discomfort and facilitates recovery after surgery.

How It Works

  • Ibuprofen B. Braun works by reversibly inhibiting cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes, which blocks the conversion of arachidonic acid to prostaglandins. The resulting reduction in prostaglandin synthesis diminishes peripheral sensitisation, lowers fever set‑points in the hypothalamus, and limits inflammatory exudate formation.

Side Effects

Adverse reactions may occur with any NSAID therapy.

Common Side Effects

  • Gastrointestinal discomfort: nausea, dyspepsia or mild abdominal pain.
  • Headache: transient headache occurring shortly after administration.
  • Dizziness: occasional light‑headedness or vertigo.
  • Injection site reactions: mild erythema or tenderness at the IV site.

Serious or Rare Side Effects

  • Bleeding: gastrointestinal or systemic hemorrhage, especially with anticoagulants.
  • Renal impairment: acute kidney injury or worsening chronic kidney disease.
  • Severe hypersensitivity: anaphylaxis, Stevens‑Johnson syndrome or toxic epidermal necrolysis.

Precautions & Warnings

Careful assessment and monitoring are required before and during therapy.

  • Renal function: assess baseline kidney function and monitor in patients with renal impairment.
  • Bleeding risk: avoid in patients with active bleeding or those receiving anticoagulant therapy.
  • Asthma: use cautiously in individuals with aspirin‑sensitive asthma.
  • Pregnancy: evaluate risk‑benefit; avoid in the third trimester when possible.
  • Drug interactions: review concomitant NSAIDs, anticoagulants or other interacting agents.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Ibuprofen B. Braun may interact with several medication classes.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of serious bleeding.
  • Other NSAIDs: additive gastrointestinal toxicity and ulcer risk.
  • SSRIs or SNRIs: heightened bleeding tendency.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors: possible reduction in renal function, especially in volume‑depleted patients.
  • Diuretics: increased risk of renal impairment.
  • Lithium: ibuprofen can raise serum lithium concentrations, requiring monitoring.

Frequently Asked Questions

Ibuprofen B. Braun is an intravenous formulation of the NSAID ibuprofen. It is used in hospital settings to provide analgesic, antipyretic and anti‑inflammatory effects for conditions such as acute pain, fever, inflammatory disorders and postoperative discomfort.

Ibuprofen inhibits the cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which are essential for converting arachidonic acid into prostaglandins. By reducing prostaglandin production, it lowers pain signalling, decreases fever, and limits inflammation at the site of injury.

The specific dose and infusion rate of Ibuprofen B. Braun are determined by the prescribing clinician based on the patient’s age, weight, clinical condition and response. Healthcare professionals follow local guidelines and product labeling to set the appropriate regimen.

Safety data for intravenous ibuprofen in pregnancy are limited, and the product is classified as having an unknown pregnancy category. It should only be used when the potential benefit justifies any potential risk, and it is generally avoided in the third trimester. Breastfeeding mothers should consult their physician before use.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain handling) and any necessary import documentation.

Ibuprofen B. Braun offers the same COX‑inhibitory profile as oral ibuprofen but provides rapid, controlled plasma concentrations via intravenous administration. Compared with ketorolac, another IV NSAID, ibuprofen generally has a lower risk of severe gastrointestinal bleeding but may require higher doses for equivalent analgesia.

The injectable solution must be stored refrigerated at 2‑8 °C, protected from light, and should never be frozen or shaken. Before use, inspect the vial for particulate matter and ensure the solution is at room temperature if required by the administration protocol.

Ibuprofen B. Braun is administered intravenously by slow infusion, typically over 15‑30 minutes, depending on the prescribed dose and clinical setting. Administration should be performed by qualified healthcare personnel using aseptic technique and appropriate IV equipment.

The most serious risks include severe bleeding (especially when combined with anticoagulants), acute kidney injury, and rare but life‑threatening hypersensitivity reactions such as anaphylaxis or Stevens‑Johnson syndrome. Prompt recognition and discontinuation are essential if these events occur.

Patients with known hypersensitivity to ibuprofen or any NSAID, those with active gastrointestinal bleeding, severe renal impairment, uncontrolled hypertension, or aspirin‑sensitive asthma should avoid this product. It is also contraindicated in the third trimester of pregnancy unless clearly indicated by a physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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