Product image of Ibuprofen B. Braun (Ibuprofen) supplied by GNH India

Ibuprofen B. Braun

Active Ingredient:
Ibuprofen
Origin:
EU

Ibuprofen B. Braun (Ibuprofen)

Ibuprofen, the active ingredient in Ibuprofen B. Braun, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an intravenous solution for intravenous use. It treats mild to moderate pain, fever, inflammation, and post‑operative pain in hospital patients.

GNH India supplies Ibuprofen B. Braun as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, clinics and healthcare institutions worldwide.

Manufacturer / TM Owner

B.Braun Melsungen Ag

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Indications & Clinical Uses

Ibuprofen is an NSAID that reduces pain, fever, and inflammation by inhibiting prostaglandin synthesis.

  • Mild to moderate pain: provides analgesia for surgical or injury‑related discomfort.
  • Fever: lowers elevated body temperature.
  • Inflammation: decreases swelling associated with postoperative or musculoskeletal conditions.

How It Works

  • Ibuprofen exerts its effect by non‑selectively inhibiting cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes, which blocks the conversion of arachidonic acid to prostaglandins. The reduction in prostaglandin synthesis diminishes peripheral sensitization of nociceptors, lowers the hypothalamic set‑point for temperature, and limits inflammatory exudate formation.

Side Effects

Adverse reactions may occur with intravenous ibuprofen administration.

Common Side Effects

  • Nausea or vomiting.
  • Headache.
  • Transient rise in blood pressure.
  • Injection site discomfort or phlebitis.

Serious or Rare Side Effects

  • Gastrointestinal bleeding or ulceration.
  • Acute kidney injury, especially in volume‑depleted patients.
  • Severe hypersensitivity reactions such as anaphylaxis or Stevens‑Johnson syndrome.

Precautions & Warnings

Use ibuprofen intravenously only under professional supervision and consider patient‑specific risk factors.

  • Renal function: assess baseline creatinine and avoid in severe renal impairment.
  • Cardiovascular risk: monitor blood pressure and avoid in uncontrolled hypertension.
  • Gastrointestinal history: use cautiously in patients with ulcer disease or bleeding disorders.
  • Coagulation status: be aware of increased bleeding risk, especially with anticoagulants.
  • Pregnancy and lactation: evaluate risk‑benefit ratio; data are limited for IV use.
  • Store at ambient temperature: keep in original container, protect from light and moisture.

Avoid Interactions

Ibuprofen may interact with several drug classes, requiring clinical awareness.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): may amplify bleeding risk.
  • High‑dose aspirin or other NSAIDs: can increase nephrotoxicity and gastrointestinal injury.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: may reduce renal perfusion, especially in dehydrated patients.
  • Diuretics: combined use can impair renal function.
  • Lithium: ibuprofen can raise serum lithium levels.
  • Methotrexate: may decrease renal clearance, raising toxicity risk.

Frequently Asked Questions

Ibuprofen B. Braun is an intravenous formulation of ibuprofen used in hospital settings to manage mild to moderate pain, reduce fever, and control inflammation, including postoperative swelling and musculoskeletal discomfort.

Ibuprofen works by non‑selectively blocking the cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which reduces the production of prostaglandins. Lower prostaglandin levels decrease peripheral nerve sensitization, lower the hypothalamic temperature set‑point, and limit inflammatory fluid accumulation.

The specific dose and infusion rate of Ibuprofen B. Braun are determined by the prescribing clinician based on the patient’s age, weight, clinical condition, and renal or hepatic function. The product label provides guidance, but the final regimen is individualized.

Safety data for intravenous ibuprofen in pregnancy and lactation are limited. Clinicians should weigh potential benefits against risks, especially in the third trimester, and consider alternative therapies when possible. Breastfeeding mothers should consult a healthcare professional before use.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and import documentation.

Compared with other IV NSAIDs, ibuprofen offers a well‑characterized safety profile and effective analgesia for mild to moderate pain. Unlike opioid analgesics, it does not cause respiratory depression, but it shares class‑related risks such as renal impairment and gastrointestinal bleeding, which must be monitored.

Ibuprofen B. Braun should be stored at ambient temperature, below 25 °C, in its original sealed container. Protect the solution from direct sunlight, moisture, and extreme temperature fluctuations to maintain stability.

The product is supplied as a sterile intravenous solution. It is administered by a qualified healthcare professional through an IV line, typically as a slow infusion over several minutes, following the dosing instructions provided by the prescriber.

Serious risks include gastrointestinal bleeding or ulceration, acute kidney injury, severe hypersensitivity reactions such as anaphylaxis, and cardiovascular events like hypertension or thrombotic complications, particularly in patients with pre‑existing risk factors.

Patients with known hypersensitivity to ibuprofen or other NSAIDs, active gastrointestinal bleeding, severe renal or hepatic impairment, uncontrolled hypertension, or those receiving anticoagulant therapy without close monitoring should generally avoid this medication.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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