Product image of Ibuprofen B. Braun (Ibuprofen) supplied by GNH India

Ibuprofen B. Braun

Active Ingredient:
Ibuprofen
Origin:
EU

Ibuprofen B. Braun (Ibuprofen)

Ibuprofen, the active ingredient in Ibuprofen B. Braun, is a nonsteroidal anti‑inflammatory drug (NSAID) presented as an intravenous solution for intravenous use. It treats mild to moderate pain, fever and inflammation in hospital patients. Its intravenous formulation provides rapid onset of analgesia, making it suitable for acute care environments.

GNH India supplies Ibuprofen B. Braun as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres, oncology centres, pharmacies and clinics worldwide, with manufacturing adhering to European Union standards and rigorous quality controls.

Manufacturer / TM Owner

B.Braun Melsungen Ag

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Indications & Clinical Uses

Ibuprofen, an NSAID, reduces inflammation and pain by inhibiting cyclooxygenase enzymes.

  • Mild to moderate pain: provides analgesia for postoperative or injury‑related discomfort
  • Fever: lowers elevated body temperature
  • Inflammation: decreases swelling associated with musculoskeletal conditions

How It Works

  • Ibuprofen reversibly inhibits both cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes, blocking the conversion of arachidonic acid to prostaglandins. This reduction in prostaglandin synthesis diminishes inflammation, pain signaling, and fever generation at the site of tissue injury or infection.

Side Effects

Adverse reactions may vary in frequency and severity.

Common Side Effects

  • Nausea: mild to moderate upset stomach
  • Dyspepsia: indigestion or heartburn
  • Headache: transient cranial discomfort
  • Dizziness: light‑headed sensation
  • Injection site pain: local discomfort at the IV site
  • Transient rise in serum creatinine: mild renal function change

Serious or Rare Side Effects

  • Gastrointestinal bleeding: potentially life‑threatening hemorrhage
  • Anaphylaxis: severe allergic reaction with airway compromise
  • Stevens‑Johnson syndrome: rare severe skin eruption
  • Acute renal failure: abrupt loss of kidney function
  • Hepatic necrosis: serious liver injury
  • Thrombotic cardiovascular events: increased risk of heart attack or stroke

Precautions & Warnings

Careful assessment and monitoring are required before and during therapy.

  • Renal impairment: monitor kidney function and adjust dose if needed
  • Bleeding risk: avoid in patients with active ulcers or on anticoagulants
  • Asthma: use cautiously in aspirin‑sensitive asthmatic patients
  • Pregnancy: avoid unless clearly indicated and benefits outweigh risks
  • Drug interactions: review concomitant NSAIDs, anticoagulants, and other interacting agents
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake

Avoid Interactions

Ibuprofen may interact with several drug classes, requiring vigilance.

Major Interactions (Avoid)

  • Other NSAIDs: additive gastrointestinal bleeding risk
  • Anticoagulants (e.g., warfarin, DOACs): heightened bleeding tendency
  • Corticosteroids: increased ulceration risk

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: possible reduction in renal function
  • Loop diuretics: monitor electrolytes and kidney parameters
  • Lithium: NSAIDs may raise lithium serum concentrations

Frequently Asked Questions

Ibuprofen B. Braun is an intravenous formulation of ibuprofen, an NSAID used in hospital settings to manage mild to moderate pain, reduce fever, and control inflammation associated with surgical procedures, injuries, or acute medical conditions.

Ibuprofen works by reversibly inhibiting the cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which blocks the synthesis of prostaglandins—molecules that mediate pain, fever, and inflammation—thereby providing analgesic, antipyretic, and anti‑inflammatory effects.

The specific dose and infusion rate of Ibuprofen B. Braun are determined by the prescribing clinician based on the patient’s condition, weight, renal function, and therapeutic goals. Only a qualified healthcare professional should set the dosing regimen.

The safety of intravenous ibuprofen in pregnancy has not been established, and it is generally avoided unless the potential benefit justifies the risk. Limited data exist for breastfeeding; clinicians should assess risks and consider alternative therapies when possible.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

Compared with other injectable NSAIDs such as ketorolac, ibuprofen offers a similar mechanism of COX inhibition but may have a slightly longer half‑life and a different safety profile, particularly regarding renal and gastrointestinal effects. Choice of agent depends on clinical judgment, patient comorbidities, and institutional protocols.

Ibuprofen B. Braun should be stored refrigerated at 2‑8 °C, protected from light, and must not be frozen or shaken. Before administration, inspect the solution for particulate matter or discoloration and use aseptic technique as per hospital pharmacy standards.

The product is supplied as a sterile intravenous solution and is administered by slow infusion through a dedicated IV line under the supervision of qualified medical personnel. The infusion rate and total volume are set by the prescriber according to the clinical situation.

Serious risks include gastrointestinal bleeding, severe allergic reactions such as anaphylaxis, acute renal failure, hepatic injury, and thrombotic cardiovascular events. Patients should be monitored closely for signs of bleeding, renal dysfunction, or hypersensitivity during therapy.

Ibuprofen B. Braun is contraindicated in patients with known hypersensitivity to ibuprofen or other NSAIDs, active gastrointestinal ulceration or bleeding, severe uncontrolled heart failure, and in those receiving certain anticoagulants where bleeding risk is unacceptable. Clinicians must evaluate individual contraindications before prescribing.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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