Product image of Ibuprofen B. Braun (Ibuprofen) supplied by GNH India

Ibuprofen B. Braun

Active Ingredient:
Ibuprofen
Origin:
EU

Ibuprofen B. Braun (Ibuprofen)

Ibuprofen, the active ingredient in Ibuprofen B. Braun, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an intravenous solution for intravenous use. It treats mild to moderate pain, fever, and inflammation in adult patients requiring rapid systemic therapy.

GNH India supplies Ibuprofen B. Braun as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

B.Braun Melsungen Ag

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Indications & Clinical Uses

Ibuprofen, an NSAID that reduces prostaglandin-mediated inflammation, is indicated for several acute and postoperative conditions.

  • Mild to moderate pain: provides analgesia for surgical and injury‑related discomfort.
  • Fever: lowers elevated body temperature in acute febrile states.
  • Post‑operative pain: controls pain following surgical procedures.
  • Musculoskeletal pain: alleviates pain from strains, sprains and joint inflammation.
  • Inflammation: decreases swelling in acute inflammatory conditions.

How It Works

  • Ibuprofen reversibly inhibits cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes, which blocks the conversion of arachidonic acid to prostaglandins. The reduction in prostaglandin synthesis diminishes peripheral sensitisation, lowers the hypothalamic set‑point for temperature, and limits the inflammatory cascade, resulting in analgesic, antipyretic and anti‑inflammatory effects.

Side Effects

Adverse reactions may range from mild to serious and should be monitored during therapy.

Common Side Effects

  • Nausea: mild gastrointestinal upset.
  • Headache: transient cranial discomfort.
  • Dizziness: occasional light‑headedness.
  • Injection site pain: local discomfort at the IV site.

Serious or Rare Side Effects

  • Anaphylaxis: severe allergic reaction requiring immediate medical attention.
  • Gastrointestinal bleeding: ulceration or hemorrhage in the digestive tract.
  • Renal impairment: acute kidney injury, especially in volume‑depleted patients.
  • Cardiovascular thrombotic events: increased risk of heart attack or stroke.

Precautions & Warnings

Before initiating therapy, clinicians should evaluate patient‑specific risk factors and follow safe handling practices.

  • Renal function: assess baseline kidney function and adjust use in renal impairment.
  • Bleeding risk: avoid in patients with active ulcers or concurrent anticoagulant therapy.
  • Cardiovascular status: use cautiously in patients with heart failure or uncontrolled hypertension.
  • Pregnancy: avoid unless benefits outweigh potential risks; safety category is unknown.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Ibuprofen can interact with several drug classes, requiring careful review of the patient’s medication list.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of bleeding.
  • Other NSAIDs: additive gastrointestinal toxicity.
  • ACE inhibitors or ARBs: heightened risk of renal dysfunction.
  • Lithium: elevated lithium serum concentrations.
  • Methotrexate: reduced clearance leading to toxicity.

Moderate Interactions (Monitor Closely)

  • Diuretics: potential for reduced renal perfusion.
  • Corticosteroids: increased gastrointestinal ulcer risk.

Frequently Asked Questions

Ibuprofen B. Braun is an intravenous formulation of ibuprofen used to provide rapid relief of mild to moderate pain, reduce fever, and control inflammation in acute or postoperative settings. It is administered in hospitals and clinical environments where a fast‑acting systemic NSAID is required.

Ibuprofen works by reversibly inhibiting the cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which are essential for the production of prostaglandins. By lowering prostaglandin levels, it reduces pain signalling, lowers elevated body temperature, and diminishes the inflammatory response.

The specific dose and infusion rate of Ibuprofen B. Braun are determined by the prescribing clinician based on the patient’s condition, weight, renal function, and therapeutic goals. Healthcare providers follow local guidelines and product labeling to set the appropriate regimen.

The safety of ibuprofen in pregnancy is not well established, and the product is classified as having an unknown pregnancy category. It should only be used if the potential benefit justifies the potential risk to the fetus. Breastfeeding mothers should consult their physician, as ibuprofen can be excreted in milk.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.

Compared with other IV NSAIDs such as ketorolac, ibuprofen offers a similar analgesic and antipyretic profile but may have a slightly lower risk of renal toxicity at equivalent doses. Unlike opioid analgesics, ibuprofen does not cause respiratory depression, making it a useful component of multimodal pain management.

Ibuprofen B. Braun should be stored refrigerated at 2‑8 °C, protected from light, and must not be frozen or shaken. Before administration, the solution should be inspected for particulate matter and discoloration, and any unused portion should be discarded according to local regulations.

The product is given as an intravenous infusion, typically diluted in compatible IV fluids and administered over a short period as directed by the prescriber. Administration should be performed by qualified healthcare personnel using aseptic technique and appropriate infusion equipment.

Serious risks include severe allergic reactions such as anaphylaxis, gastrointestinal bleeding or ulceration, acute kidney injury, and cardiovascular events like myocardial infarction or stroke. Patients should be monitored for signs of these events, especially if they have pre‑existing risk factors.

Ibuprofen B. Braun is contraindicated in patients with known hypersensitivity to ibuprofen or other NSAIDs, active gastrointestinal bleeding, severe uncontrolled hypertension, advanced heart failure, and in the third trimester of pregnancy. Clinicians should also avoid use in patients with significant renal impairment unless benefits outweigh risks.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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