Product image of Ibuprofen B. Braun (Ibuprofen) supplied by GNH India

Ibuprofen B. Braun

Active Ingredient:
Ibuprofen
Origin:
EU

Ibuprofen B. Braun (Ibuprofen)

Ibuprofen, the active ingredient in Ibuprofen B. Braun, is a NSAID presented as an injection solution for intravenous use. It treats pain, fever, and inflammation in adult patients.
GNH India supplies Ibuprofen B. Braun as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals worldwide.

Manufacturer / TM Owner

B.Braun Melsungen Ag

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Indications & Clinical Uses

  • Ibuprofen is a non‑steroidal anti‑inflammatory drug that reduces pain, fever, and inflammation.
  • Pain: provides analgesic relief for mild to moderate acute pain
  • Fever: lowers elevated body temperature in febrile conditions
  • Inflammation: diminishes inflammatory response in postoperative or musculoskeletal inflammation

How It Works

  • Ibuprofen reversibly inhibits cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, decreasing the conversion of arachidonic acid to prostaglandins. The reduced prostaglandin synthesis leads to lowered inflammation, diminished peripheral sensitization of nociceptors, and a decrease in the hypothalamic set‑point for body temperature, thereby providing analgesic, antipyretic, and anti‑inflammatory effects.

Side Effects

Adverse reactions may occur with intravenous ibuprofen administration.

Common Side Effects

  • Nausea
  • Vomiting
  • Dyspepsia
  • Headache
  • Dizziness
  • Injection‑site pain

Serious or Rare Side Effects

  • Gastrointestinal bleeding or ulceration
  • Acute renal impairment
  • Severe allergic reaction (anaphylaxis)
  • Stevens‑Johnson syndrome or toxic epidermal necrolysis
  • Hepatic dysfunction
  • Thrombocytopenia

Precautions & Warnings

  • Use ibuprofen injection with careful clinical assessment.
  • Assess renal function: evaluate baseline creatinine and adjust use in renal impairment
  • Monitor gastrointestinal risk: avoid in patients with active ulcers or bleeding disorders
  • Evaluate cardiovascular status: use cautiously in patients with hypertension or heart disease
  • Use caution in asthma or known NSAID allergy: watch for bronchospasm or hypersensitivity
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake

Avoid Interactions

Ibuprofen may interact with several medications.

Major Interactions (Avoid)

  • Warfarin: increased risk of bleeding
  • Other NSAIDs: additive gastrointestinal toxicity
  • Lithium: elevated lithium levels

Moderate Interactions (Monitor Closely)

  • ACE inhibitors: possible reduction in renal function
  • Diuretics: enhanced risk of renal impairment
  • SSRIs: increased potential for bleeding

Frequently Asked Questions

Ibuprofen B. Braun is an intravenous formulation of ibuprofen used in hospital settings to provide rapid relief of moderate pain, reduce fever, and control inflammation associated with surgical procedures, musculoskeletal injuries, or other acute inflammatory conditions.

Ibuprofen works by reversibly blocking the cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which are essential for converting arachidonic acid into prostaglandins. Lower prostaglandin levels reduce inflammation, decrease pain signal amplification, and lower the hypothalamic set‑point for temperature, producing analgesic, antipyretic, and anti‑inflammatory effects.

The specific dose and infusion rate of Ibuprofen B. Braun are determined by the prescribing clinician based on the patient’s age, weight, clinical condition, and therapeutic goals. Healthcare professionals follow local guidelines and product labeling to set the appropriate regimen.

Safety data for intravenous ibuprofen in pregnancy and lactation are limited, and the product’s pregnancy category is listed as unknown. Clinicians should weigh potential benefits against risks and consider alternative therapies when treating pregnant or nursing patients.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed), and import documentation.

Ibuprofen B. Braun offers a non‑selective COX inhibition profile similar to other injectable NSAIDs such as ketorolac, but it may have a slightly lower risk of renal toxicity at comparable doses. Choice of agent depends on the clinical scenario, patient comorbidities, and physician preference.

The product must be stored refrigerated between 2 °C and 8 °C, protected from light, and should never be frozen or shaken. Prior to administration, inspect the solution for particulate matter and ensure the vial is within its expiry date.

Ibuprofen B. Braun is given as an intravenous infusion. The vial is diluted with an appropriate compatible solution and administered over the recommended time period, typically 15–30 minutes, under aseptic conditions by qualified healthcare personnel.

Serious risks include gastrointestinal bleeding or ulceration, acute renal failure, severe hypersensitivity reactions such as anaphylaxis, and rare but life‑threatening skin reactions like Stevens‑Johnson syndrome. Patients should be monitored closely for signs of these events.

Ibuprofen B. Braun is contraindicated in patients with known hypersensitivity to ibuprofen or other NSAIDs, active gastrointestinal bleeding or ulceration, severe renal impairment, and those who have experienced previous severe allergic reactions to injectable NSAIDs.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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