Product image of Ibuprofen B. Braun (Ibuprofen) supplied by GNH India

Ibuprofen B. Braun

Active Ingredient:
Ibuprofen
Origin:
EU

Ibuprofen B. Braun (Ibuprofen)

Ibuprofen, the active ingredient in Ibuprofen B. Braun, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an intravenous formulation for parenteral use. It treats pain, fever and inflammation in adult patients, including postoperative settings.

GNH India supplies Ibuprofen B. Braun as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

B.Braun Melsungen Ag

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Indications & Clinical Uses

Ibuprofen, an NSAID that reduces prostaglandin‑mediated inflammation, is indicated for the following conditions:

  • Pain: provides analgesia for mild to moderate acute pain.
  • Fever: lowers elevated body temperature.
  • Inflammation: reduces swelling and inflammatory response.
  • Postoperative pain: manages pain following surgical procedures.

How It Works

  • Ibuprofen exerts its effect by reversibly inhibiting the cyclooxygenase enzymes COX‑1 and COX‑2. This inhibition decreases the synthesis of prostaglandins, which are key mediators of pain, fever, and inflammation, thereby producing analgesic, antipyretic, and anti‑inflammatory actions.

Side Effects

Adverse reactions may occur with intravenous ibuprofen use.

Common Side Effects

  • Nausea
  • Dyspepsia
  • Headache
  • Dizziness
  • Injection‑site pain or erythema
  • Transient increase in serum creatinine

Serious or Rare Side Effects

  • Gastrointestinal bleeding or ulceration
  • Severe renal impairment
  • Anaphylactic or severe hypersensitivity reactions
  • Stevens‑Johnson syndrome or toxic epidermal necrolysis
  • Cardiovascular thrombotic events such as myocardial infarction
  • Hepatotoxicity

Precautions & Warnings

When using intravenous ibuprofen, consider the following precautions:

  • Renal function: monitor in patients with existing renal impairment.
  • Hepatic function: use cautiously in liver disease.
  • Cardiovascular risk: avoid in patients with active coronary artery disease.
  • Bleeding risk: assess before surgical or invasive procedures.
  • Pregnancy: avoid unless benefits outweigh potential risks.
  • Store at ambient temperature: keep in original packaging, protect from moisture and light.

Avoid Interactions

Ibuprofen may interact with several medicines; awareness of these interactions helps ensure safe use.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): heightened risk of bleeding.
  • ACE inhibitors (e.g., lisinopril): possible decline in renal function.
  • Lithium: increased serum lithium concentrations.

Moderate Interactions (Monitor Closely)

  • SSRIs (e.g., sertraline): additive bleeding tendency.
  • Diuretics (e.g., furosemide): may affect renal clearance.

Frequently Asked Questions

Ibuprofen B. Braun is an intravenous NSAID indicated for the management of acute pain, fever, and inflammation, including postoperative pain, in adult patients treated in hospital or clinical settings.

Ibuprofen works by reversibly inhibiting the cyclooxygenase enzymes COX‑1 and COX‑2, which reduces the production of prostaglandins—key mediators of pain, fever, and inflammatory processes.

The appropriate dose is determined by the prescribing clinician based on the patient’s condition, weight, renal function, and other clinical factors. Dosing regimens are individualized and should follow the prescriber’s instructions.

Safety in pregnancy has not been established; it should be avoided, especially in the third trimester, unless the potential benefit justifies the risk. Caution is also advised during breastfeeding, and the prescriber should evaluate the risk‑benefit balance.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.

Compared with alternatives such as IV ketorolac, ibuprofen offers a similar analgesic and antipyretic profile but may have a slightly lower risk of renal adverse effects at equivalent doses. Choice between agents depends on individual patient factors, safety considerations, and institutional protocols.

Store the product at ambient temperature below 25 °C. Keep it in the original container, protect from moisture and direct light, and ensure the vial remains sealed until use to maintain sterility.

Ibuprofen B. Braun is administered intravenously by a qualified healthcare professional. The sterile solution is infused over a short period, typically via a peripheral or central IV line, according to the prescriber’s dosing instructions.

Serious risks include gastrointestinal bleeding or ulceration, severe renal impairment, anaphylactic reactions, Stevens‑Johnson syndrome, and cardiovascular thrombotic events such as myocardial infarction. Patients should be monitored for signs of these conditions during therapy.

Contraindications include patients with known hypersensitivity to ibuprofen or other NSAIDs, active gastrointestinal ulcer or bleeding, severe renal or hepatic impairment, uncontrolled hypertension, and women in the third trimester of pregnancy.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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