Product image of Ibuprofen B. Braun Melsungen (Ibuprofen) supplied by GNH India

Ibuprofen B. Braun Melsungen

Active Ingredient:
Ibuprofen
Origin:
EU

Ibuprofen B. Braun Melsungen (Ibuprofen)

Ibuprofen, the active ingredient in Ibuprofen B. Braun Melsungen, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an intravenous solution for intravenous use. It treats mild to moderate pain, post‑operative pain, musculoskeletal pain and fever in adult patients.

GNH India supplies Ibuprofen B. Braun Melsungen as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, providing reliable, quality‑assured products for acute‑care settings.

Manufacturer / TM Owner

B.Braun Melsungen Ag

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Indications & Clinical Uses

Ibuprofen is an NSAID that reduces inflammation and pain by inhibiting prostaglandin synthesis.

  • Mild to moderate pain: provides rapid analgesia for acute pain episodes.
  • Post‑operative pain: helps control discomfort after surgical procedures.
  • Musculoskeletal pain: alleviates pain associated with strains, sprains and arthritis.
  • Fever: lowers elevated body temperature in febrile patients.

How It Works

  • Ibuprofen non‑selectively inhibits cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes, decreasing the conversion of arachidonic acid to prostaglandins. The reduction in prostaglandin levels diminishes inflammation, pain signaling, and fever generation, producing its analgesic, antipyretic, and anti‑inflammatory effects.

Side Effects

Adverse reactions may occur with intravenous ibuprofen and are categorized by frequency.

Common Side Effects

  • Nausea: mild to moderate upset stomach.
  • Dyspepsia: indigestion or stomach discomfort.
  • Headache: transient cranial pain.
  • Injection site pain or erythema: local irritation at the infusion site.

Serious or Rare Side Effects

  • Gastrointestinal bleeding or ulceration: potentially life‑threatening hemorrhage.
  • Acute kidney injury: impaired renal function, especially in at‑risk patients.
  • Severe allergic reaction (anaphylaxis): rapid onset of airway or circulatory compromise.
  • Liver enzyme elevation or hepatitis: signs of hepatic injury.

Precautions & Warnings

Prior to administration, clinicians should consider several safety measures.

  • Assess renal function: adjust or avoid use in patients with significant kidney impairment.
  • Monitor gastrointestinal risk: avoid in individuals with active ulcers or recent GI bleeding.
  • Use caution in cardiovascular disease: NSAIDs may increase blood pressure or exacerbate heart failure.
  • Avoid in known hypersensitivity to ibuprofen or other NSAIDs.
  • Pregnancy and lactation: consult the prescriber as safety data are limited.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Ibuprofen can interact with other medicines, requiring careful management.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of bleeding.
  • Other NSAIDs or COX‑2 inhibitors: additive gastrointestinal and renal toxicity.
  • Corticosteroids: heightened risk of GI ulceration.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: may impair renal function when combined.
  • Lithium: ibuprofen can raise serum lithium concentrations, risking toxicity.

Frequently Asked Questions

Ibuprofen B. Braun Melsungen is an intravenous formulation of ibuprofen used to manage mild to moderate pain, post‑operative discomfort, musculoskeletal pain, and fever in hospital settings. It provides rapid analgesic and antipyretic effects when administered by infusion.

Ibuprofen works by non‑selectively inhibiting the cyclooxygenase enzymes COX‑1 and COX‑2, which reduces the synthesis of prostaglandins. Lower prostaglandin levels diminish inflammation, pain signaling, and fever, delivering its therapeutic benefits.

The specific dose and infusion rate are determined by the prescribing clinician based on the patient’s condition, weight, and clinical response. Healthcare professionals follow local guidelines and product labeling to set the appropriate regimen.

Safety of intravenous ibuprofen in pregnancy and lactation has not been fully established. Prescribers should evaluate the risk‑benefit profile for each patient and consider alternative therapies when safety data are limited.

Submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed) and import documentation.

Intravenous ibuprofen offers rapid onset of analgesia compared with oral NSAIDs, which may be advantageous in acute care. Its non‑selective COX inhibition is similar to other NSAIDs, but the IV route bypasses gastrointestinal absorption, potentially reducing oral‑related GI irritation.

The product should be stored at 2‑8 °C, kept refrigerated, protected from light, and must not be frozen or shaken. Use aseptic technique during preparation and administer according to the manufacturer’s infusion guidelines.

Ibuprofen B. Braun Melsungen is given as an intravenous infusion. The solution is diluted in compatible IV fluids and infused over the time period recommended in the prescribing information, typically ranging from a few minutes to an hour depending on the dose.

Serious risks include gastrointestinal bleeding or ulceration, acute kidney injury, severe allergic reactions such as anaphylaxis, and liver injury. Patients should be monitored for signs of bleeding, renal dysfunction, rash, or hepatic abnormalities during treatment.

Patients with known hypersensitivity to ibuprofen or other NSAIDs, active gastrointestinal ulceration or bleeding, severe renal or hepatic impairment, uncontrolled heart failure, or those on anticoagulant therapy without careful monitoring should avoid using this product.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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