Product image of Ibuprofen Bluefish (Ibuprofen) supplied by GNH India

Ibuprofen Bluefish

Active Ingredient:
Ibuprofen
Origin:
EU

Ibuprofen Bluefish (Ibuprofen)

Ibuprofen, the active ingredient in Ibuprofen Bluefish, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an oral dosage form for oral use. It treats pain, fever and inflammation in adults and children when prescribed by a healthcare professional.

GNH India supplies Ibuprofen Bluefish as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies, clinics and procurement teams worldwide.

Manufacturer / TM Owner

Bluefish Pharmaceuticals Ab

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Indications & Clinical Uses

Ibuprofen acts on inflammatory pathways to relieve several common conditions.

  • Pain: Reduces mild to moderate acute or chronic pain such as headache, dental pain or musculoskeletal discomfort.
  • Fever: Lowers elevated body temperature associated with infections or inflammatory states.
  • Inflammation: Decreases swelling and stiffness in conditions like osteoarthritis and rheumatoid arthritis.
  • Arthritis: Improves joint function and reduces pain in various arthritic disorders.

How It Works

  • Ibuprofen exerts its effect by reversibly inhibiting the cyclooxygenase enzymes COX‑1 and COX‑2. This blockade reduces the conversion of arachidonic acid to prostaglandins, which are mediators of pain, fever and inflammation. By lowering prostaglandin levels, ibuprofen diminishes the sensitization of nerve endings and the inflammatory response.

Side Effects

Ibuprofen may cause a range of adverse reactions, varying from mild to severe.

Common Side Effects

  • Gastrointestinal discomfort: nausea, dyspepsia or abdominal pain.
  • Headache: mild to moderate intensity.
  • Dizziness or vertigo.
  • Rash or mild skin irritation.
  • Elevated blood pressure in some patients.

Serious or Rare Side Effects

  • Gastrointestinal bleeding or ulceration.
  • Severe allergic reactions such as anaphylaxis or angioedema.
  • Cardiovascular events including myocardial infarction or stroke.
  • Renal impairment or acute kidney injury.
  • Hepatotoxicity with elevated liver enzymes.

Precautions & Warnings

When using ibuprofen, consider the following precautions to minimize risks.

  • Assess gastrointestinal risk: avoid in patients with active ulcers or history of GI bleeding.
  • Evaluate cardiovascular status: use cautiously in those with hypertension, heart disease or stroke risk.
  • Monitor renal function: limit use in patients with chronic kidney disease or dehydration.
  • Review concomitant medications: avoid combining with other NSAIDs, anticoagulants or corticosteroids without supervision.
  • Pregnancy and lactation: consult a healthcare professional before use during pregnancy or while breastfeeding.
  • Store at ambient temperature: keep below 25 °C in the original packaging, protected from moisture and direct sunlight.

Avoid Interactions

Ibuprofen can interact with several medicines, requiring attention to avoid reduced efficacy or increased toxicity.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of serious bleeding.
  • Selective serotonin reuptake inhibitors (SSRIs): heightened bleeding tendency.
  • High‑dose aspirin: additive gastrointestinal toxicity.
  • ACE inhibitors or ARBs: may diminish antihypertensive effect and impair renal function.
  • Lithium: increased lithium levels leading to toxicity.

Moderate Interactions (Monitor Closely)

  • Diuretics: possible reduction in renal perfusion.
  • Methotrexate: decreased clearance, raising toxicity risk.
  • Corticosteroids: enhanced risk of gastrointestinal ulceration.
  • Cyclosporine: increased nephrotoxicity potential.
  • Antidiabetic drugs: may affect blood glucose control.

Frequently Asked Questions

Ibuprofen Bluefish is a generic ibuprofen product indicated for the relief of mild to moderate pain, reduction of fever, and management of inflammatory conditions such as osteoarthritis, rheumatoid arthritis and other musculoskeletal disorders, when prescribed by a qualified healthcare professional.

Ibuprofen works by reversibly inhibiting the cyclooxygenase enzymes COX‑1 and COX‑2, which are essential for converting arachidonic acid into prostaglandins. By lowering prostaglandin synthesis, it reduces the signals that cause pain, fever and inflammation, providing symptomatic relief.

The appropriate dose and dosing schedule are determined by the prescriber based on the patient’s age, weight, clinical condition and response to therapy. Healthcare providers select the strength, frequency and duration that best match the individual’s therapeutic needs; patients should follow the prescribed regimen exactly.

Safety of ibuprofen during pregnancy and lactation depends on the stage of pregnancy and clinical judgment. It is generally avoided in the third trimester because of potential fetal cardiovascular effects, and should only be used in earlier trimesters or while breastfeeding when clearly needed and under medical supervision.

To place an order, submit an enquiry on the Ibuprofen Bluefish product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and the necessary import documentation.

Ibuprofen and acetaminophen both relieve pain and reduce fever, but they differ in mechanism and safety profile. Ibuprofen, an NSAID, also has anti‑inflammatory activity and can affect platelet function and the gastrointestinal lining, whereas acetaminophen lacks anti‑inflammatory effects and has a lower risk of GI irritation but carries a risk of liver toxicity at high doses.

Ibuprofen Bluefish should be stored at ambient temperature, preferably below 25 °C. Keep the product in its original packaging, protect it from moisture, direct sunlight and excessive heat, and ensure the container is tightly closed to maintain stability throughout its shelf life.

Ibuprofen Bluefish is intended for oral administration. The tablets (or other oral dosage form) should be swallowed whole with a full glass of water, preferably with food or milk to lessen gastrointestinal discomfort, unless the prescriber provides alternative instructions.

The most serious risks include gastrointestinal bleeding or ulceration, cardiovascular events such as heart attack or stroke, severe allergic reactions (anaphylaxis, angioedema), and renal impairment that can lead to acute kidney injury. Patients experiencing any of these symptoms should seek immediate medical attention.

Ibuprofen should be avoided by individuals with a known hypersensitivity to ibuprofen or other NSAIDs, those with active gastrointestinal ulcers or bleeding, patients with severe heart failure, uncontrolled hypertension, advanced renal disease, and by anyone in the third trimester of pregnancy unless specifically directed by a healthcare professional.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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