Product image of Ibuprofen Brillpharma (Ireland) (Ibuprofen) supplied by GNH India

Ibuprofen Brillpharma (Ireland)

Active Ingredient:
Ibuprofen
Origin:
EU

Ibuprofen Brillpharma (Ireland) (Ibuprofen)

Ibuprofen, the active ingredient in Ibuprofen Brillpharma, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an oral dosage form for oral use. It is used to relieve pain, reduce fever, and control inflammation in adults and children when appropriate.

GNH India supplies Ibuprofen Brillpharma as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Brillpharma (Ireland) Limited

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Indications & Clinical Uses

Ibuprofen acts as an NSAID to manage symptoms associated with inflammatory and febrile conditions.

  • Pain relief: reduces mild to moderate pain such as headache, dental or musculoskeletal discomfort.
  • Fever reduction: lowers elevated body temperature caused by infection or inflammation.
  • Inflammation control: diminishes swelling and stiffness in conditions like arthritis or soft‑tissue injury.

How It Works

  • Ibuprofen inhibits cyclooxygenase enzymes COX‑1 and COX‑2, decreasing the conversion of arachidonic acid to prostaglandins. This reduction in prostaglandin synthesis lowers inflammation, pain signaling, and the hypothalamic set‑point for body temperature, providing analgesic, antipyretic, and anti‑inflammatory effects.

Side Effects

Adverse reactions may vary in frequency and severity.

Common Side Effects

  • Gastrointestinal upset: nausea, dyspepsia, or heartburn.
  • Headache or dizziness.
  • Mild skin rash.
  • Elevated blood pressure.

Serious or Rare Side Effects

  • Gastrointestinal bleeding or ulceration.
  • Severe allergic reactions such as anaphylaxis or Stevens‑Johnson syndrome.
  • Acute kidney injury or worsening of chronic renal disease.
  • Hepatotoxicity with marked liver enzyme elevation.
  • Cardiovascular events including myocardial infarction or stroke.
  • Hematologic abnormalities like thrombocytopenia.

Precautions & Warnings

Before using Ibuprofen, consider the following safety measures.

  • Renal function assessment: evaluate kidney health, especially in the elderly or those with chronic disease.
  • Lowest effective dose: use the smallest dose needed for symptom control to limit adverse effects.
  • Hypersensitivity caution: avoid if a known allergy to ibuprofen or other NSAIDs exists.
  • Anticoagulant interaction: monitor bleeding risk when combined with warfarin, aspirin, or similar agents.
  • Gastrointestinal monitoring: watch for signs of ulceration or bleeding, particularly with prolonged use.
  • Store at room temperature: keep in the original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Ibuprofen can affect the activity of several other medicines.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of serious bleeding.
  • High‑dose aspirin: heightened gastrointestinal toxicity.
  • Selective serotonin reuptake inhibitors (SSRIs): elevated bleeding potential.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: may reduce renal perfusion, especially in volume‑depleted patients.
  • Diuretics: possible decrease in antihypertensive effect and renal function.
  • Lithium: ibuprofen can raise lithium levels, requiring serum monitoring.

Frequently Asked Questions

Ibuprofen Brillpharma is employed to relieve mild to moderate pain, lower fever, and reduce inflammation associated with conditions such as headaches, dental pain, musculoskeletal injuries, arthritis, and febrile illnesses. It provides symptomatic relief by targeting the underlying inflammatory pathways.

Ibuprofen blocks the cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which are essential for converting arachidonic acid into prostaglandins. By lowering prostaglandin levels, it diminishes pain signals, reduces fever, and curtails inflammation at the site of tissue injury or infection.

The appropriate dose of Ibuprofen Brillpharma is determined by the prescribing healthcare professional based on the patient’s age, weight, clinical condition, and response to therapy. Patients should follow the prescriber’s instructions and the product labeling.

Safety of ibuprofen during pregnancy and lactation depends on the trimester and individual risk factors. Generally, ibuprofen is avoided in the third trimester and used with caution earlier. Breastfeeding mothers should consult their physician, as small amounts may be excreted in milk.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Ibuprofen shares the core mechanism of COX inhibition with other NSAIDs but differs in its pharmacokinetic profile, dosing frequency, and gastrointestinal safety margin. Compared with agents like naproxen or diclofenac, ibuprofen often has a shorter half‑life, allowing flexible dosing but may require more frequent administration for sustained effect.

Ibuprofen Brillpharma should be stored at room temperature, below 25 °C, in its original container. Protect the product from moisture, direct sunlight, and extreme temperatures to maintain potency and stability throughout its shelf life.

The medication is taken orally, usually with a full glass of water. It can be taken with or without food, although taking it with meals may reduce stomach irritation. Follow the prescriber’s guidance on timing and frequency.

Serious risks include gastrointestinal bleeding or ulceration, severe allergic reactions such as anaphylaxis, acute kidney injury, liver dysfunction, and increased cardiovascular events like heart attack or stroke, especially with high‑dose or prolonged use.

Individuals with known hypersensitivity to ibuprofen or other NSAIDs, active gastrointestinal ulcers, severe heart failure, uncontrolled hypertension, or those on anticoagulant therapy without close monitoring should avoid this medication. Consultation with a healthcare professional is essential before use.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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