Product image of Ibuprofen Bristol Laboratories (Ibuprofen) supplied by GNH India

Ibuprofen Bristol Laboratories

Active Ingredient:
Ibuprofen
Origin:
EU

Ibuprofen Bristol Laboratories (Ibuprofen)

Ibuprofen, the active ingredient in Ibuprofen Bristol Laboratories, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an oral dosage form for oral use. It treats pain, fever, inflammation and arthritis in adults and children as directed by a healthcare professional.

GNH India supplies Ibuprofen Bristol Laboratories as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Bristol Laboratories Limited

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Indications & Clinical Uses

Ibuprofen acts as an analgesic and antipyretic within the NSAID drug class, reducing inflammation and pain.

  • Pain: Provides relief for mild to moderate acute pain such as headache, dental or musculoskeletal discomfort.
  • Fever: Lowers elevated body temperature associated with infections or inflammatory conditions.
  • Inflammation: Decreases swelling and redness in conditions like sprains or minor injuries.
  • Arthritis: Alleviates joint pain and stiffness in osteoarthritis and rheumatoid arthritis.

How It Works

  • Ibuprofen inhibits cyclooxygenase enzymes COX‑1 and COX‑2, which blocks the conversion of arachidonic acid to prostaglandins. By reducing prostaglandin synthesis, it diminishes inflammation, pain signaling, and fever generation at the site of tissue injury or infection.

Side Effects

Adverse reactions may vary in frequency and severity.

Common Side Effects

  • Nausea: mild stomach upset or queasiness.
  • Dyspepsia: indigestion or heartburn.
  • Headache: transient mild headache.
  • Dizziness: occasional light‑headed feeling.
  • Rash: mild skin irritation or itching.
  • Diarrhoea: loose stools.

Serious or Rare Side Effects

  • Gastrointestinal bleeding: black stools or vomiting blood.
  • Peptic ulcer: persistent abdominal pain.
  • Renal impairment: reduced urine output or swelling.
  • Severe allergic reaction: swelling of face, lips, or throat, difficulty breathing.
  • Hepatic injury: jaundice or abnormal liver tests.

Precautions & Warnings

Before using ibuprofen, consider the following safety measures.

  • Assess renal function: evaluate kidney health, especially in the elderly or dehydrated patients.
  • Evaluate gastrointestinal risk: avoid in individuals with active ulcers or history of GI bleeding.
  • Review cardiovascular status: use cautiously in patients with hypertension or heart disease.
  • Monitor concomitant medications: check for drugs that increase bleeding risk.
  • Avoid use in late pregnancy: discuss alternatives with a healthcare provider.
  • Store at below 25°C: keep in the original pack, protect from moisture and direct sunlight.

Avoid Interactions

Ibuprofen can affect the activity of several other medicines.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of serious bleeding.
  • Other NSAIDs: additive gastrointestinal toxicity.
  • Lithium: higher lithium serum concentrations.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: possible reduction in antihypertensive effect.
  • Diuretics: may diminish diuretic efficacy and affect kidney function.
  • SSRIs: heightened risk of gastrointestinal bleeding.

Frequently Asked Questions

Ibuprofen Bristol Laboratories is used to relieve mild to moderate pain, reduce fever, and lessen inflammation associated with conditions such as headaches, dental pain, musculoskeletal injuries, and various forms of arthritis. It works across a broad range of acute and chronic inflammatory conditions as directed by a prescriber.

Ibuprofen works by blocking the cyclooxygenase‑1 and cyclooxygenase‑2 (COX‑1 and COX‑2) enzymes, which are essential for producing prostaglandins. Prostaglandins mediate pain, fever, and inflammation, so their reduction leads to decreased discomfort, lower body temperature, and reduced swelling at the site of injury.

The appropriate dose of ibuprofen is determined by the prescribing healthcare professional based on the patient’s age, weight, medical condition, and treatment goals. Patients should follow the prescriber’s instructions and the product label, and never exceed the recommended amount without medical advice.

Ibuprofen should be used with caution during pregnancy, especially in the third trimester, because it may affect fetal cardiovascular development. While limited data exist for breastfeeding, small amounts can pass into milk. Women who are pregnant or nursing should discuss alternatives with their healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Ibuprofen shares the same COX‑inhibiting mechanism as other NSAIDs such as naproxen and diclofenac, but it has a relatively short half‑life, which may require more frequent dosing. Its safety profile is comparable, though individual tolerability and specific drug‑interaction risks can differ, making clinician selection important.

Store the product at temperatures below 25 °C (77 °F). Keep it in the original packaging to protect it from moisture and direct sunlight. Do not store in a bathroom or near a heat source, and keep out of reach of children.

Ibuprofen Bristol Laboratories is taken orally, usually with a full glass of water. It can be taken with or without food; however, taking it with food or milk may reduce stomach irritation. Swallow tablets or capsules whole; do not crush or chew unless the formulation specifically allows it.

Serious risks include gastrointestinal bleeding or ulceration, especially in high‑risk patients, and renal impairment that can lead to reduced kidney function. Rare but severe allergic reactions such as anaphylaxis, as well as cardiovascular events like heart attack or stroke, may also occur, particularly with long‑term use.

Individuals with a known allergy to ibuprofen or other NSAIDs, those with active gastrointestinal ulcers, severe heart failure, uncontrolled hypertension, or significant kidney disease should avoid ibuprofen. Pregnant women in the third trimester and patients on certain anticoagulants should also consult a healthcare professional before use.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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