Product image of Ibuprofen Catalent (Ibuprofen) supplied by GNH India

Ibuprofen Catalent

Active Ingredient:
Ibuprofen
Origin:
EU

Ibuprofen Catalent (Ibuprofen)

Ibuprofen, the active ingredient in Ibuprofen Catalent, is a Nonsteroidal anti-inflammatory drug (NSAID) presented as an oral dosage form for oral use. It is used to relieve pain, reduce fever, and diminish inflammation in adults and children when appropriate. It is indicated for short‑term management of mild to moderate symptoms and is available in various strengths to suit clinical needs.

GNH India supplies Ibuprofen Catalent as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, with a focus on quality assurance and regulatory compliance across EU and global markets.

Manufacturer / TM Owner

Catalent Germany Eberbach Gmbh

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Indications & Clinical Uses

  • Ibuprofen acts as an analgesic, antipyretic and anti‑inflammatory agent by inhibiting cyclo‑oxygenase enzymes.
  • Pain: provides relief of mild to moderate pain such as headache, dental or musculoskeletal discomfort.
  • Fever: reduces elevated body temperature associated with infections or inflammatory conditions.
  • Inflammation: decreases swelling and redness in conditions like arthritis or soft‑tissue injury.

How It Works

  • Ibuprofen reversibly inhibits both cyclo‑oxygenase‑1 (COX‑1) and cyclo‑oxygenase‑2 (COX‑2) enzymes, leading to decreased conversion of arachidonic acid to prostaglandins. The reduction in prostaglandin synthesis diminishes peripheral sensitization of nociceptors, lowers the hypothalamic set‑point for temperature regulation, and limits inflammatory mediators, thereby producing analgesic, antipyretic, and anti‑inflammatory effects.

Side Effects

Ibuprofen may cause a range of adverse reactions, varying from mild to serious.

Common Side Effects

  • Nausea
  • Dyspepsia
  • Headache
  • Dizziness

Serious or Rare Side Effects

  • Gastrointestinal bleeding or ulceration
  • Severe allergic reactions such as anaphylaxis or angioedema
  • Hepatic injury manifested by elevated liver enzymes
  • Renal impairment including acute kidney injury

Precautions & Warnings

  • Before initiating therapy, consider patient‑specific factors and follow safe‑use practices.
  • Assess medical history: review gastrointestinal, cardiovascular, renal and hepatic conditions before use.
  • Avoid in patients with known NSAID hypersensitivity: discontinue if allergic reaction occurs.
  • Use lowest effective dose for shortest duration: minimize risk of adverse events.
  • Monitor in elderly or patients on anticoagulants: increased bleeding risk.
  • Store at room temperature: keep in original container, protect from moisture and heat.

Avoid Interactions

Ibuprofen can interact with several drug classes; some combinations should be avoided while others require monitoring.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of bleeding.
  • Concomitant NSAIDs or aspirin: additive gastrointestinal toxicity.
  • Corticosteroids: heightened risk of ulceration and bleeding.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: may reduce renal function, especially in volume‑depleted patients.
  • Lithium: ibuprofen can raise lithium serum concentrations, necessitating level checks.

Frequently Asked Questions

Ibuprofen Catalent contains ibuprofen, an NSAID that is used to relieve mild to moderate pain, lower fever, and reduce inflammation. It is commonly prescribed for conditions such as headache, dental pain, musculoskeletal aches, fever associated with infections, and inflammatory disorders like arthritis.

Ibuprofen works by reversibly blocking the cyclo‑oxygenase‑1 and cyclo‑oxygenase‑2 enzymes, which are needed for the production of prostaglandins. By lowering prostaglandin levels, it reduces the sensitisation of pain receptors, lowers the hypothalamic set‑point for temperature, and diminishes the inflammatory response.

The appropriate dose of ibuprofen is determined by the prescribing healthcare professional based on the patient’s age, weight, condition being treated, and overall health status. Dosage instructions are provided on the prescription label and should be followed exactly as directed.

Ibuprofen is generally avoided during the third trimester of pregnancy because it may affect fetal cardiovascular function. During earlier stages, it should only be used if clearly needed and prescribed. Ibuprofen passes into breast milk in small amounts; mothers should consult a healthcare provider before using it while breastfeeding.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and the necessary import documentation.

The primary alternative to ibuprofen is acetaminophen (paracetamol), which provides analgesic and antipyretic effects but lacks significant anti‑inflammatory activity. Ibuprofen’s anti‑inflammatory action makes it preferable for conditions involving swelling, while acetaminophen is often chosen for patients who need pain relief without the gastrointestinal risks associated with NSAIDs.

Ibuprofen Catalent should be stored at room temperature, below 25 °C. Keep the product in its original packaging, protect it from moisture and direct heat, and ensure the container is tightly closed to maintain stability throughout its shelf life.

Ibuprofen Catalent is administered orally. The tablets or capsules are swallowed whole with a full glass of water, preferably with food or milk to minimise gastrointestinal discomfort. The exact administration schedule is set by the prescriber.

Serious risks include gastrointestinal bleeding or ulceration, severe allergic reactions such as anaphylaxis, liver injury indicated by elevated enzymes, and kidney impairment that may lead to reduced renal function. Patients should seek immediate medical attention if they notice signs such as black stools, rash, swelling, or sudden decrease in urine output.

Ibuprofen should be avoided by individuals with a known hypersensitivity to ibuprofen or other NSAIDs, those with active gastrointestinal ulcers, severe heart failure, uncontrolled hypertension, or advanced kidney disease. It is also contraindicated in the third trimester of pregnancy and in patients taking certain anticoagulants without close medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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