Product image of Ibuprofen Catalent (Ibuprofen) supplied by GNH India

Ibuprofen Catalent

Active Ingredient:
Ibuprofen
Origin:
EU

Ibuprofen Catalent (Ibuprofen)

Ibuprofen, the active ingredient in Ibuprofen Catalent, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an oral dosage form for systemic use. It provides analgesic, antipyretic and anti‑inflammatory effects for the relief of pain, fever and inflammation in appropriate patient populations.

GNH India supplies Ibuprofen Catalent as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides reliable global distribution to meet the needs of healthcare providers across multiple regions.

Manufacturer / TM Owner

Catalent Germany Eberbach Gmbh

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Indications & Clinical Uses

Ibuprofen acts as an analgesic and anti‑inflammatory agent by inhibiting cyclooxygenase enzymes involved in prostaglandin synthesis.

  • Pain: Reduces mild to moderate pain such as headaches, dental pain, or musculoskeletal discomfort.
  • Fever: Lowers elevated body temperature associated with febrile illnesses.
  • Inflammation: Decreases swelling and inflammation in conditions like arthritis or minor injuries.

How It Works

  • Ibuprofen exerts its therapeutic effect by non‑selectively inhibiting the cyclooxygenase enzymes COX‑1 and COX‑2. This inhibition blocks the conversion of arachidonic acid to prostaglandin H2, reducing the synthesis of prostaglandins that mediate pain, fever and inflammation. The reduced prostaglandin levels diminish peripheral sensitization of nociceptors and lower the hypothalamic set‑point for temperature regulation.

Side Effects

Ibuprofen may cause a range of adverse reactions, varying from mild to severe.

Common Side Effects

  • Gastrointestinal discomfort: nausea, dyspepsia or abdominal pain.
  • Headache: mild to moderate intensity.
  • Dizziness: transient sensation of light‑headedness.
  • Rash: mild skin erythema or itching.

Serious or Rare Side Effects

  • Gastrointestinal bleeding: ulceration or hemorrhage in the stomach or intestines.
  • Renal impairment: reduced kidney function or acute kidney injury.
  • Hepatotoxicity: elevated liver enzymes or hepatitis.
  • Severe hypersensitivity: anaphylaxis, angioedema or Stevens‑Johnson syndrome.

Precautions & Warnings

When using ibuprofen, several safety considerations should be observed to minimize risk.

  • Assess renal function: avoid use in patients with severe kidney disease or dehydration.
  • Monitor gastrointestinal risk: use with caution in individuals with a history of ulcers or bleeding.
  • Evaluate cardiovascular status: limit use in patients with uncontrolled hypertension or heart failure.
  • Consider pregnancy and lactation: discuss risks with a healthcare professional before use.
  • Review concomitant medications: avoid combining with other NSAIDs or anticoagulants without guidance.
  • Store at ambient temperature: keep below 25 °C, protect from moisture and light in the original container.

Avoid Interactions

Ibuprofen can interact with other medicines, altering their effectiveness or safety profile.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of serious bleeding.
  • High‑dose aspirin: heightened gastrointestinal toxicity.
  • Selective serotonin reuptake inhibitors (SSRIs): elevated bleeding risk.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: may reduce renal protective effects.
  • Diuretics: potential for reduced diuretic efficacy and kidney function.
  • Lithium: ibuprofen may increase lithium serum levels.
  • Methotrexate: possible increase in methotrexate toxicity.

Frequently Asked Questions

Ibuprofen Catalent is used to relieve mild to moderate pain, reduce fever, and decrease inflammation. It is commonly prescribed for conditions such as headaches, dental pain, musculoskeletal aches, feverish illnesses, and inflammatory disorders like arthritis, providing symptomatic relief in appropriate patient groups.

Ibuprofen works by non‑selectively inhibiting the cyclooxygenase enzymes COX‑1 and COX‑2. This blocks the conversion of arachidonic acid to prostaglandins, which are key mediators of pain, fever, and inflammation. Lower prostaglandin levels result in reduced sensation of pain, a lowered fever set‑point, and diminished inflammatory swelling.

The specific dose of ibuprofen is determined by the prescribing healthcare professional based on the patient’s age, weight, condition being treated, and overall health status. Dosage recommendations may vary, and patients should follow the prescriber’s instructions and the product labeling for safe use.

Safety of ibuprofen in pregnancy and lactation depends on the trimester and individual risk factors. Generally, ibuprofen is avoided in the third trimester because of potential fetal cardiovascular effects, and caution is advised throughout pregnancy. During breastfeeding, small amounts pass into milk; a healthcare professional should evaluate the risk‑benefit ratio before use.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity of Ibuprofen Catalent. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

Ibuprofen belongs to the NSAID class, whereas acetaminophen (paracetamol) is an analgesic/antipyretic with minimal anti‑inflammatory activity. Ibuprofen provides stronger anti‑inflammatory effects but carries higher gastrointestinal and renal risk, while acetaminophen is gentler on the stomach but can affect the liver at high doses. Choice depends on the clinical need and patient risk profile.

Ibuprofen Catalent should be stored at ambient temperature, preferably below 25 °C, in its original packaging to protect it from moisture and light. Keep the product out of reach of children and avoid storing it in areas with high humidity or direct sunlight to maintain its stability and potency.

Ibuprofen Catalent is administered orally, typically as a tablet or capsule that is swallowed whole with a full glass of water. It can be taken with or without food, although taking it with food may reduce gastrointestinal discomfort. Patients should follow the prescriber’s directions regarding timing and frequency.

Serious risks include gastrointestinal bleeding or ulceration, severe renal impairment, hepatotoxicity, and hypersensitivity reactions such as anaphylaxis or Stevens‑Johnson syndrome. Patients should be alert for signs of black stools, sudden kidney dysfunction, unusual liver enzyme elevations, or severe skin rashes and seek immediate medical attention if these occur.

Ibuprofen should be avoided by individuals with known hypersensitivity to ibuprofen or other NSAIDs, those with active gastrointestinal bleeding or ulcer disease, severe renal or hepatic impairment, uncontrolled hypertension, and patients in the third trimester of pregnancy. It should also be used with caution in patients taking anticoagulants, certain antihypertensives, or other NSAIDs.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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