Product image of Ibuprofen Catalent (Ibuprofen) supplied by GNH India

Ibuprofen Catalent

Active Ingredient:
Ibuprofen
Origin:
EU

Ibuprofen Catalent (Ibuprofen)

Ibuprofen, the active ingredient in Ibuprofen Catalent, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an oral formulation for oral use. It treats mild to moderate pain, fever and inflammation in adults and children as directed by a healthcare professional.

GNH India supplies Ibuprofen Catalent as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Zaklady Farmaceutyczne Polpharma S.A.

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Indications & Clinical Uses

Ibuprofen, a nonsteroidal anti-inflammatory drug, is employed to manage conditions that involve pain, fever or inflammation.

  • Mild to moderate pain: provides analgesic relief for headaches, dental pain, musculoskeletal discomfort, and menstrual cramps.
  • Fever: reduces elevated body temperature associated with infections or inflammatory states.
  • Osteoarthritis: alleviates joint pain and improves functional mobility.
  • Rheumatoid arthritis: helps control inflammatory joint pain and swelling.
  • General inflammation: diminishes swelling and redness in soft‑tissue injuries.

How It Works

  • Ibuprofen exerts its effect by reversibly inhibiting both cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes, which blocks the conversion of arachidonic acid to prostaglandins. The resulting decrease in prostaglandin synthesis reduces inflammation, lowers fever, and provides analgesia at peripheral sites of pain and inflammation.

Side Effects

Adverse reactions may range from mild to severe and should be monitored during therapy.

Common Side Effects

  • Gastrointestinal discomfort: nausea, dyspepsia, or abdominal pain.
  • Headache: mild to moderate intensity.
  • Dizziness or vertigo.
  • Skin rash or mild itching.
  • Elevated blood pressure in susceptible individuals.

Serious or Rare Side Effects

  • Gastrointestinal bleeding or ulceration.
  • Severe allergic reactions: angioedema, anaphylaxis.
  • Renal impairment or acute kidney injury.
  • Hepatotoxicity: elevated liver enzymes.
  • Cardiovascular events: increased risk of myocardial infarction or stroke in high‑risk patients.

Precautions & Warnings

Before initiating therapy, consider the following safety measures.

  • Assess renal function: avoid or adjust dose in patients with existing kidney disease.
  • Evaluate gastrointestinal risk: use the lowest effective dose and consider gastro‑protective agents for high‑risk individuals.
  • Monitor cardiovascular status: exercise caution in patients with known heart disease or hypertension.
  • Check for hypersensitivity: discontinue immediately if signs of allergic reaction appear.
  • Use lowest effective dose: limit duration to the shortest period necessary for symptom control.
  • Store at ambient temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Ibuprofen may interact with several drug classes, requiring careful management.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of bleeding.
  • Selective COX‑2 inhibitors: additive gastrointestinal toxicity.
  • Lithium: ibuprofen can raise serum lithium concentrations, leading to toxicity.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: may reduce renal perfusion, especially in volume‑depleted patients.
  • Diuretics: combined use can impair kidney function.
  • Methotrexate: ibuprofen may decrease clearance, raising toxicity risk.

Frequently Asked Questions

Ibuprofen Catalent is an oral NSAID indicated for the relief of mild to moderate pain, reduction of fever, and mitigation of inflammation associated with conditions such as osteoarthritis, rheumatoid arthritis, and common musculoskeletal injuries. It is prescribed by healthcare professionals based on individual patient needs.

Ibuprofen works by reversibly inhibiting the cyclooxygenase enzymes COX‑1 and COX‑2, which are essential for the synthesis of prostaglandins. By lowering prostaglandin levels, it reduces inflammation, alleviates pain, and helps lower elevated body temperature.

The appropriate dose of Ibuprofen Catalent is determined by the prescribing clinician, who considers factors such as the patient’s age, weight, severity of symptoms, renal and hepatic function, and any concomitant medications. No fixed regimen is provided here.

Safety data for ibuprofen during pregnancy are limited, especially in the third trimester, where it may affect fetal cardiovascular function. Breastfeeding mothers should consult a healthcare professional, as ibuprofen does pass into breast milk in small amounts. Professional guidance is essential before use.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.

Ibuprofen shares the core mechanism of COX inhibition with other NSAIDs but is often preferred for its relatively balanced COX‑1/COX‑2 profile, which offers effective analgesia with a moderate gastrointestinal risk compared with non‑selective agents like naproxen. It is generally less potent than selective COX‑2 inhibitors for chronic inflammatory conditions but has a well‑established safety record when used at recommended doses.

Store Ibuprofen Catalent at ambient temperature, preferably below 25 °C. Keep the product in its original packaging, protect it from moisture and direct sunlight, and ensure the container is tightly closed to maintain stability throughout its shelf life.

Ibuprofen Catalent is taken orally, usually with a full glass of water. It may be taken with or without food; however, taking it with food can help reduce potential gastrointestinal discomfort. The exact administration schedule should follow the prescriber’s instructions.

Serious risks include gastrointestinal bleeding or ulceration, severe allergic reactions such as anaphylaxis, renal impairment, and increased cardiovascular events like heart attack or stroke, particularly in patients with existing heart disease. Patients should seek immediate medical attention if they notice signs of bleeding, severe rash, swelling, or chest pain.

Individuals with known hypersensitivity to ibuprofen or any other NSAID, those with active gastrointestinal ulcers, severe heart failure, uncontrolled hypertension, or advanced renal or hepatic disease should avoid using Ibuprofen Catalent unless specifically directed by a physician. Pregnant women in the third trimester should also refrain from use.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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