Product image of Ibuprofen Da (Ibuprofen) supplied by GNH India

Ibuprofen Da

Active Ingredient:
Ibuprofen
Origin:
EU

Ibuprofen Da (Ibuprofen)

Ibuprofen, the active ingredient in Ibuprofen Da, is a nonsteroidal anti‑inflammatory drug (NSAID) presented as an unknown/unknown for oral use. It treats pain, fever, inflammation and arthritis in adults and children as appropriate.

GNH India supplies Ibuprofen Da as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Nederlandse Drogisterij Service B.V.

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Indications & Clinical Uses

Ibuprofen acts on inflammatory pathways to relieve several common conditions.

  • Pain: reduces mild to moderate pain such as headache, dental or musculoskeletal discomfort.
  • Fever: lowers elevated body temperature associated with infections or inflammatory states.
  • Inflammation: diminishes swelling and redness in conditions like sprains or bursitis.
  • Arthritis: eases joint pain and stiffness in osteoarthritis and rheumatoid arthritis.

How It Works

  • Ibuprofen inhibits cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes, decreasing the conversion of arachidonic acid to prostaglandins. The reduced prostaglandin synthesis lessens inflammation, pain signaling, and fever generation at peripheral and central sites.

Side Effects

Adverse reactions may range from mild to severe and should be monitored.

Common Side Effects

  • Nausea: occasional upset stomach.
  • Dyspepsia: indigestion or heartburn.
  • Headache: mild to moderate.
  • Dizziness: transient light‑headedness.
  • Rash: mild skin irritation.
  • Diarrhoea: loose stools.

Serious or Rare Side Effects

  • Gastrointestinal ulcer or bleeding: potentially life‑threatening.
  • Renal impairment: reduced kidney function.
  • Cardiovascular events: increased risk of heart attack or stroke.
  • Severe skin reactions: Stevens‑Johnson syndrome or toxic epidermal necrolysis.
  • Anaphylaxis: rare but severe allergic response.

Precautions & Warnings

Before using Ibuprofen Da, consider the following safety measures.

  • Assess gastrointestinal risk: avoid in patients with active ulcers or a history of GI bleeding.
  • Evaluate renal function: use caution in those with impaired kidney function.
  • Monitor cardiovascular status: limit use in patients with heart disease or hypertension.
  • Use the lowest effective dose: minimize exposure while achieving therapeutic effect.
  • Avoid in known hypersensitivity: discontinue if allergic reactions occur.
  • Store at below 25°C: keep in the original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Ibuprofen can interact with several medicines; awareness helps prevent adverse outcomes.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased bleeding risk.
  • Other NSAIDs: additive gastrointestinal toxicity.
  • Corticosteroids: heightened ulcer risk.
  • ACE inhibitors or ARBs: possible reduction in renal function.
  • Lithium: elevated lithium serum levels.

Moderate Interactions (Monitor Closely)

  • Diuretics: may enhance renal effects.
  • Antihypertensives: possible attenuation of blood‑pressure control.
  • Methotrexate: reduced clearance leading to toxicity.
  • SSRIs: modest increase in bleeding tendency.
  • Oral hypoglycemics: potential alteration of glucose control.

Frequently Asked Questions

Ibuprofen Da is an over‑the‑counter formulation of ibuprofen that is used to relieve mild to moderate pain, reduce fever, and decrease inflammation associated with conditions such as headaches, dental pain, musculoskeletal injuries, and various forms of arthritis.

Ibuprofen works by blocking the cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which are essential for the production of prostaglandins. Lower prostaglandin levels result in reduced inflammation, diminished pain signaling, and a lowered fever response.

The appropriate dose of Ibuprofen Da is determined by a qualified prescriber or pharmacist based on the individual’s age, weight, medical condition, and response to therapy. Patients should follow the specific instructions provided on the label or by their healthcare professional.

Safety of ibuprofen in pregnancy and lactation depends on the trimester and individual risk factors. It is generally avoided in the third trimester and used only when clearly needed in earlier stages. Breastfeeding mothers should consult a healthcare professional before use.

To place an order, submit an enquiry on the Ibuprofen Da product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Ibuprofen provides anti‑inflammatory, analgesic, and antipyretic effects, whereas acetaminophen mainly offers pain relief and fever reduction without significant anti‑inflammatory activity. Compared with other NSAIDs, ibuprofen has a relatively short half‑life and is often preferred for short‑term use, but all NSAIDs share similar gastrointestinal and cardiovascular risk profiles.

Store Ibuprofen Da at temperatures below 25 °C in its original container, protecting it from moisture, direct sunlight, and excessive heat. Keep the product out of reach of children and do not use it after the expiration date printed on the packaging.

Ibuprofen Da is taken orally with a full glass of water. It may be taken with food or milk to lessen stomach irritation. Swallow tablets or capsules whole; do not crush or chew unless the product label specifically permits it.

The most serious risks include gastrointestinal bleeding or ulceration, severe kidney injury, and increased cardiovascular events such as heart attack or stroke. Patients should be alert for signs of black stools, unexplained bruising, sudden weight gain, or swelling and seek medical attention promptly.

Ibuprofen Da should be avoided by individuals with known hypersensitivity to ibuprofen or other NSAIDs, active gastrointestinal ulcers, severe heart failure, uncontrolled hypertension, advanced renal disease, or those who are in the third trimester of pregnancy. Consultation with a healthcare professional is essential before starting therapy.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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