Product image of Ibuprofen Dermogen (Ibuprofen) supplied by GNH India

Ibuprofen Dermogen

Active Ingredient:
Ibuprofen
Origin:
EU

Ibuprofen Dermogen (Ibuprofen)

Ibuprofen, the active ingredient in Ibuprofen Dermogen, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an oral dosage form for oral use. It is used to relieve mild to moderate pain, reduce fever, and manage inflammatory conditions such as arthritis in adults and children when appropriate.

GNH India supplies Ibuprofen Dermogen as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Dermogen Farma, S.A.

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Indications & Clinical Uses

Ibuprofen acts on the cyclooxygenase pathway to provide analgesic, antipyretic and anti‑inflammatory effects.

  • Pain (mild to moderate): offers effective relief of everyday aches and postoperative discomfort.
  • Fever: lowers elevated body temperature in febrile states.
  • Arthritis (inflammatory joint conditions): reduces joint swelling and pain associated with osteoarthritis and rheumatoid arthritis.
  • Dental pain: helps control discomfort after dental procedures.
  • Musculoskeletal injuries: eases pain and inflammation from sprains, strains and soft‑tissue trauma.

How It Works

  • Ibuprofen inhibits both cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes, decreasing the conversion of arachidonic acid to prostaglandins. The reduction in prostaglandin synthesis diminishes peripheral sensitisation of nociceptors, lowers the hypothalamic set‑point for temperature, and limits inflammatory mediators that cause swelling and pain.

Side Effects

Adverse reactions may range from mild to serious, depending on patient factors and concomitant therapies.

Common Side Effects

  • Gastrointestinal upset: nausea, dyspepsia or abdominal discomfort.
  • Headache: transient mild to moderate head pain.
  • Dizziness: occasional light‑headed sensation.
  • Skin rash: mild erythema or itching.

Serious or Rare Side Effects

  • Gastrointestinal bleeding or ulceration.
  • Acute renal impairment, especially in volume‑depleted patients.
  • Severe allergic reactions such as anaphylaxis or angioedema.

Precautions & Warnings

Before initiating therapy, consider the following safety measures.

  • Assess renal function: adjust use in patients with impaired kidney function.
  • Monitor gastrointestinal health: avoid in active ulcer disease or severe gastritis.
  • Avoid concurrent anticoagulants: increased risk of bleeding.
  • Use caution in asthma: NSAIDs may exacerbate bronchospasm.
  • Store at ambient temperature below 25°C: keep in the original pack, protect from moisture.

Avoid Interactions

Ibuprofen can interact with several drug classes, requiring attention to dosing and monitoring.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): heightened bleeding risk.
  • Other NSAIDs or COX‑2 inhibitors: additive gastrointestinal toxicity.
  • Lithium therapy: ibuprofen may raise serum lithium concentrations.

Moderate Interactions (Monitor Closely)

  • Diuretics (e.g., thiazides): may reduce renal clearance of ibuprofen.
  • ACE inhibitors or ARBs: potential attenuation of antihypertensive effect.

Frequently Asked Questions

Ibuprofen Dermogen contains ibuprofen, an NSAID that is commonly prescribed to relieve mild to moderate pain, lower fever, and reduce inflammation associated with conditions such as arthritis, dental pain, and musculoskeletal injuries.

Ibuprofen works by inhibiting the cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which blocks the formation of prostaglandins. This reduction in prostaglandin levels decreases pain signaling, lowers body temperature, and diminishes inflammatory swelling.

The appropriate dose of Ibuprofen Dermogen is determined by a qualified prescriber based on the patient’s age, condition, and overall health. Dosage instructions are provided on the prescription label and should be followed exactly as directed.

Safety of ibuprofen during pregnancy and lactation depends on the trimester and individual risk factors. Generally, ibuprofen is avoided in the third trimester and used only if clearly needed earlier in pregnancy. Breastfeeding mothers should consult their healthcare provider before use.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Ibuprofen is a non‑selective NSAID with a well‑established efficacy and safety profile. Compared with selective COX‑2 inhibitors, ibuprofen may have a slightly higher risk of gastrointestinal irritation but a lower cardiovascular risk. Choice of NSAID should be guided by patient‑specific factors and physician judgment.

Ibuprofen Dermogen should be stored at ambient temperature below 25 °C, in its original packaging, and protected from moisture and direct sunlight. Keep the product out of reach of children and do not use after the expiry date indicated on the label.

Ibuprofen Dermogen is taken orally, usually with a full glass of water. It may be taken with or without food, although taking it with food can help reduce gastrointestinal discomfort. Swallow tablets whole; do not crush or chew unless the formulation specifically permits it.

The most serious risks include gastrointestinal bleeding or ulceration, severe allergic reactions such as anaphylaxis, and acute kidney injury, especially in patients with pre‑existing renal disease or dehydration. Prompt medical attention is required if any of these serious events occur.

Ibuprofen Dermogen should be avoided in individuals with known hypersensitivity to ibuprofen or other NSAIDs, active peptic ulcer disease, severe heart failure, or significant renal impairment. It is also contraindicated in the third trimester of pregnancy and should be used with caution in patients with asthma.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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