Product image of Ibuprofen Eg (Ibuprofen) supplied by GNH India

Ibuprofen Eg

Active Ingredient:
Ibuprofen
Origin:
EU

Ibuprofen Eg (Ibuprofen)

Ibuprofen, the active ingredient in Ibuprofen Eg, is a Nonsteroidal anti-inflammatory drug (NSAID) presented as an oral tablet for oral use. It relieves pain, reduces fever, and diminishes inflammation in adults and children when prescribed by a healthcare professional.

GNH India supplies Ibuprofen Eg as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Eurogenerics N.V./S.A.

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Indications & Clinical Uses

Ibuprofen acts systemically to modulate inflammatory pathways and is commonly employed for the following conditions:

  • Pain: provides analgesia for mild to moderate acute or chronic pain.
  • Fever: lowers elevated body temperature associated with infection or inflammation.
  • Inflammation: reduces swelling and discomfort in musculoskeletal or soft‑tissue inflammatory states.

How It Works

  • Ibuprofen exerts its effect by non‑selectively inhibiting cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes, which blocks the conversion of arachidonic acid to prostaglandins. The resulting decrease in prostaglandin synthesis diminishes peripheral sensitisation, fever generation, and inflammatory exudate formation, producing analgesic, antipyretic, and anti‑inflammatory outcomes.

Side Effects

Adverse reactions may range from mild to severe, depending on individual susceptibility and duration of therapy.

Common Side Effects

  • Nausea: mild gastrointestinal upset.
  • Dyspepsia: indigestion or stomach discomfort.
  • Headache: transient cranial pain.
  • Dizziness: occasional light‑headedness.
  • Rash: mild skin irritation.
  • Diarrhoea: loose stools.

Serious or Rare Side Effects

  • Gastrointestinal bleeding or ulceration.
  • Acute renal impairment or failure.
  • Severe allergic reactions (e.g., anaphylaxis, Stevens‑Johnson syndrome).
  • Hepatic dysfunction with elevated enzymes.
  • Cardiovascular thrombotic events (e.g., myocardial infarction, stroke).
  • Hematologic abnormalities such as thrombocytopenia.

Precautions & Warnings

Before initiating therapy, consider the following safety measures:

  • Assess gastrointestinal risk: avoid in patients with active ulcers or a history of GI bleeding.
  • Evaluate renal function: use caution in those with impaired kidney function.
  • Use the lowest effective dose: limit duration to the shortest period necessary.
  • Avoid in known hypersensitivity: discontinue if allergic reactions occur.
  • Monitor concomitant anticoagulant use: increased bleeding risk.
  • Store at room temperature: keep in the original pack, protect from moisture and direct sunlight.

Avoid Interactions

Ibuprofen can alter the pharmacokinetics or pharmacodynamics of several medicines.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): heightened bleeding risk.
  • Other NSAIDs or aspirin: additive gastrointestinal toxicity.
  • Corticosteroids: increased ulceration potential.
  • Lithium: elevated serum lithium levels.
  • Methotrexate: reduced clearance leading to toxicity.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: possible reduction in renal function.
  • Diuretics: risk of electrolyte imbalance.
  • Selective serotonin reuptake inhibitors (SSRIs): enhanced bleeding tendency.
  • Beta‑blockers: may blunt antihypertensive effect.
  • Antihypertensive agents: potential for reduced blood pressure control.

Frequently Asked Questions

Ibuprofen Eg is a generic formulation of ibuprofen, an NSAID indicated for the relief of mild to moderate pain, reduction of fever, and mitigation of inflammation associated with conditions such as musculoskeletal injuries, dental procedures, and febrile illnesses. It is prescribed by qualified healthcare professionals based on individual patient needs.

Ibuprofen works by non‑selectively inhibiting the cyclooxygenase enzymes COX‑1 and COX‑2, which are essential for converting arachidonic acid into prostaglandins. By reducing prostaglandin synthesis, ibuprofen decreases the sensitisation of pain receptors, lowers the hypothalamic set‑point for temperature, and limits the inflammatory response.

The appropriate dose of Ibuprofen Eg is determined by the prescribing clinician based on the patient’s age, weight, clinical condition, and response to therapy. Dosage recommendations are provided on the product label and must be followed as directed by a qualified healthcare professional.

Safety of ibuprofen during pregnancy and lactation depends on the trimester and individual risk factors. Generally, ibuprofen is avoided in the third trimester because of potential fetal cardiovascular effects. Breastfeeding mothers should consult their physician, as small amounts may be excreted in milk. Professional guidance is essential.

To place an order, visit the product page on gnhindia.com, enter the required quantity, and submit the enquiry form. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and import documentation.

Ibuprofen shares the core mechanism of COX inhibition with other NSAIDs such as naproxen and diclofenac, but it has a relatively shorter half‑life, which may allow for flexible dosing. Its safety profile is comparable, though individual tolerability varies; some patients may experience fewer gastrointestinal side effects with ibuprofen versus certain alternatives.

Ibuprofen Eg should be stored at room temperature, below 25 °C, in its original packaging to protect it from moisture and light. Keep the product out of reach of children and avoid storing it in bathrooms or other humid environments.

Ibuprofen Eg is intended for oral administration. Tablets should be swallowed whole with a full glass of water, preferably with food or milk to minimise gastrointestinal irritation. The exact method of intake should follow the prescribing clinician’s instructions.

Serious risks include gastrointestinal bleeding or ulceration, acute renal injury, severe allergic reactions such as anaphylaxis, and increased risk of cardiovascular events like myocardial infarction or stroke, especially with high‑dose or prolonged use. Patients should be monitored for these events and discontinue use if they occur.

Ibuprofen Eg is contraindicated in individuals with known hypersensitivity to ibuprofen or other NSAIDs, active gastrointestinal ulceration or bleeding, severe heart failure, and in the third trimester of pregnancy. Patients with significant renal or hepatic impairment should also avoid use unless specifically directed by a physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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