Product image of Ibuprofen Ennogen Pharma (Ibuprofen) supplied by GNH India

Ibuprofen Ennogen Pharma

Active Ingredient:
Ibuprofen
Origin:
EU

Ibuprofen Ennogen Pharma (Ibuprofen)

Ibuprofen, the active ingredient in Ibuprofen Ennogen Pharma, is a nonsteroidal anti-inflammatory drug presented as a tablet for oral use. It treats pain, fever, inflammation and arthritis in adults and children as directed by a healthcare professional.

GNH India supplies Ibuprofen Ennogen Pharma as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Ennogen Pharma Limited

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Indications & Clinical Uses

Ibuprofen, a nonsteroidal anti-inflammatory drug, works by inhibiting cyclooxygenase enzymes that drive pain and inflammation.

  • Pain: provides analgesic relief for mild to moderate discomfort.
  • Fever: lowers elevated body temperature.
  • Inflammation: reduces swelling and redness associated with tissue injury.
  • Arthritis: eases joint pain and stiffness in osteoarthritis and rheumatoid arthritis.

How It Works

  • Ibuprofen reversibly inhibits both cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes, decreasing the conversion of arachidonic acid to prostaglandins. This reduction in prostaglandin synthesis leads to diminished inflammation, pain perception, and fever response at the site of tissue injury.

Side Effects

Ibuprofen may cause a range of adverse reactions, from mild to severe. Awareness of common and serious events helps guide safe use.

Common Side Effects

  • Gastrointestinal upset: nausea, dyspepsia, or abdominal discomfort.
  • Headache: mild to moderate intensity.
  • Dizziness or light‑headedness.
  • Skin rash or mild itching.
  • Elevated blood pressure in some individuals.
  • Mild renal function changes.

Serious or Rare Side Effects

  • Gastrointestinal bleeding or ulcer perforation.
  • Severe allergic reactions such as anaphylaxis or Stevens‑Johnson syndrome.
  • Acute renal failure or significant decline in kidney function.
  • Hepatotoxicity with elevated liver enzymes.
  • Cardiovascular thrombotic events, including myocardial infarction or stroke.
  • Hematologic abnormalities such as thrombocytopenia.

Precautions & Warnings

Before using Ibuprofen, consider the following safety measures.

  • Assess gastrointestinal risk: avoid in patients with active ulcers or a history of GI bleeding.
  • Evaluate renal function: monitor in those with chronic kidney disease or dehydration.
  • Monitor cardiovascular status: use cautiously in patients with heart disease or hypertension.
  • Use lowest effective dose: limit duration to the shortest period needed for symptom control.
  • Avoid in known hypersensitivity: discontinue if allergic reactions occur.
  • Store at ambient temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Ibuprofen can affect the activity of several other medicines. Review the following interaction categories.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of bleeding.
  • Other NSAIDs: additive gastrointestinal toxicity.
  • Corticosteroids: heightened risk of ulceration and bleeding.

Moderate Interactions (Monitor Closely)

  • Diuretics: may reduce renal clearance of both agents.
  • Methotrexate: potential for increased methotrexate toxicity.
  • Selective serotonin reuptake inhibitors (SSRIs): elevated bleeding risk.

Frequently Asked Questions

Ibuprofen Ennogen Pharma is indicated for the relief of mild to moderate pain, reduction of fever, and management of inflammation associated with conditions such as arthritis, musculoskeletal injuries, and postoperative discomfort. It is commonly prescribed when a non‑opioid analgesic and anti‑inflammatory agent is appropriate.

Ibuprofen works by reversibly blocking the cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which are essential for converting arachidonic acid into prostaglandins. Lower prostaglandin levels reduce the sensitization of nerve endings to pain, diminish the inflammatory response, and help lower body temperature during fever.

The specific dose of Ibuprofen Ennogen Pharma is determined by the prescribing clinician based on the patient’s age, weight, clinical condition, and response to therapy. Healthcare providers select the appropriate strength, frequency, and duration according to established treatment guidelines.

Safety of ibuprofen during pregnancy and lactation depends on the trimester and individual risk factors. Generally, ibuprofen is avoided in the third trimester because of potential fetal cardiovascular effects, and caution is advised throughout pregnancy. While small amounts pass into breast milk, it is usually considered compatible with breastfeeding if the benefit outweighs risk; a healthcare professional should be consulted.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any temperature requirements), and necessary import documentation.

Ibuprofen and naproxen belong to the same NSAID class and share a similar mechanism of COX inhibition. Ibuprofen generally has a shorter half‑life, requiring more frequent dosing, whereas naproxen provides longer‑lasting relief with twice‑daily dosing. Both carry comparable gastrointestinal and cardiovascular risks, but individual patient factors and tolerability guide the choice between them.

Ibuprofen Ennogen Pharma should be stored at ambient temperature, below 25 °C, in its original packaging to protect it from moisture and direct sunlight. Keep the product out of reach of children and avoid storing in bathrooms or other humid environments.

Ibuprofen Ennogen Pharma is taken orally, usually with a full glass of water. It can be taken with or without food; however, taking it with food or milk may reduce the likelihood of gastrointestinal discomfort. Patients should follow the dosing schedule prescribed by their healthcare provider.

The most serious risks include gastrointestinal bleeding or ulcer perforation, severe allergic reactions such as anaphylaxis, acute kidney injury, and increased risk of cardiovascular events like heart attack or stroke, especially with high doses or prolonged use. Prompt medical attention is required if any of these symptoms occur.

Individuals with a known hypersensitivity to ibuprofen or other NSAIDs, active gastrointestinal ulcers, severe heart failure, uncontrolled hypertension, or significant renal impairment should avoid ibuprofen. It is also contraindicated in the third trimester of pregnancy and in patients taking certain anticoagulants without medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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