Product image of Ibuprofen Farmalider (Ibuprofen) supplied by GNH India

Ibuprofen Farmalider

Active Ingredient:
Ibuprofen
Origin:
EU

Ibuprofen Farmalider (Ibuprofen)

Ibuprofen, the active ingredient in Ibuprofen Farmalider, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an oral tablet for systemic use. It is used to relieve mild to moderate pain, reduce fever, and diminish inflammation in adults and children when appropriate. It belongs to the class of NSAIDs that act by inhibiting cyclooxygenase enzymes.

GNH India supplies Ibuprofen Farmalider as a licensed, GDP‑compliant international pharmaceutical supplier, adhering to EU GMP standards and providing the product to hospitals, pharmacies, and clinics worldwide through regulated distribution channels.

Manufacturer / TM Owner

Farmalider, S.A.

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Indications & Clinical Uses

  • Ibuprofen is an NSAID that reduces inflammation and pain by targeting prostaglandin pathways.
  • Pain: provides analgesic relief for mild to moderate acute or chronic pain.
  • Fever: lowers elevated body temperature in febrile conditions.
  • Inflammation: decreases swelling and discomfort associated with musculoskeletal disorders.

How It Works

  • Ibuprofen exerts its effect by non‑selectively inhibiting the cyclooxygenase enzymes COX‑1 and COX‑2. This inhibition blocks the conversion of arachidonic acid to prostaglandins, which are mediators of inflammation, pain, and fever. By lowering prostaglandin synthesis, ibuprofen diminishes peripheral sensitization and reduces the hypothalamic set‑point for temperature regulation.

Side Effects

Adverse reactions to ibuprofen can vary in frequency and severity.

Common Side Effects

  • Gastrointestinal discomfort or dyspepsia
  • Nausea or vomiting
  • Headache
  • Dizziness
  • Mild skin rash or itching
  • Elevated blood pressure in some patients

Serious or Rare Side Effects

  • Gastrointestinal bleeding or ulcer perforation
  • Acute renal impairment or failure
  • Hepatic enzyme elevation or liver injury
  • Severe allergic reactions such as anaphylaxis
  • Stevens‑Johnson syndrome or toxic epidermal necrolysis
  • Cardiovascular events like myocardial infarction in high‑risk individuals

Precautions & Warnings

  • When using ibuprofen, consider the following safety measures.
  • Assess renal function: evaluate kidney health before initiating therapy, especially in patients with dehydration or chronic kidney disease.
  • Monitor gastrointestinal risk: avoid use in individuals with active ulcers or a history of GI bleeding.
  • Consider cardiovascular profile: use cautiously in patients with hypertension or heart disease.
  • Avoid in late pregnancy: contraindicated during the third trimester due to fetal risks.
  • Drug interactions: review concomitant medications such as anticoagulants, antihypertensives, and other NSAIDs.
  • Store at ambient temperature: keep below 25 °C in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Ibuprofen may interact with several medicines; assess the clinical relevance before co‑administration.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of bleeding.
  • Selective serotonin reuptake inhibitors (SSRIs): heightened bleeding tendency.
  • Lithium: ibuprofen may raise lithium levels.
  • Methotrexate: reduced clearance leading to toxicity.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: may diminish renal function.
  • Diuretics: potential for reduced renal perfusion.
  • Corticosteroids: additive gastrointestinal ulcer risk.

Frequently Asked Questions

Ibuprofen Farmalider is used to relieve mild to moderate pain, reduce fever, and decrease inflammation associated with conditions such as headache, dental pain, musculoskeletal disorders, and febrile illnesses. It belongs to the NSAID class and works systemically after oral administration.

Ibuprofen works by non‑selectively inhibiting the cyclooxygenase enzymes COX‑1 and COX‑2, which blocks the conversion of arachidonic acid into prostaglandins. Lower prostaglandin levels reduce inflammation, diminish pain signaling, and reset the hypothalamic temperature set‑point, thereby lowering fever.

The dose of Ibuprofen Farmalider is determined by the prescribing healthcare professional based on the patient’s age, weight, condition, and response. Typical adult regimens range from 200 mg to 400 mg every 4‑6 hours, not exceeding the maximum daily limit, but exact dosing must follow the prescriber’s instructions.

Ibuprofen is generally avoided during the third trimester of pregnancy because of potential fetal complications. In earlier trimesters, use only if clearly needed and after consulting a healthcare provider. Limited data exist for breastfeeding; a short course may be compatible, but mothers should seek medical advice before use.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

Ibuprofen offers a relatively rapid onset of analgesic and antipyretic effect and is available in many strengths, making it versatile for short‑term use. Compared with naproxen, ibuprofen has a shorter half‑life, requiring more frequent dosing, while acetaminophen provides analgesia without anti‑inflammatory activity but lacks the COX inhibition that ibuprofen possesses.

Store the product at ambient temperature, preferably below 25 °C, in its original packaging to protect it from moisture and direct sunlight. Keep the container tightly closed and out of reach of children. Do not use if the tablet shows signs of damage or discoloration.

Ibuprofen Farmalider is taken orally with a full glass of water. It may be taken with or without food; however, taking it with food or milk can reduce the likelihood of gastrointestinal discomfort. Swallow tablets whole; do not crush or chew unless specifically instructed by a healthcare professional.

Serious risks include gastrointestinal bleeding or ulcer perforation, acute kidney injury, severe allergic reactions such as anaphylaxis, and cardiovascular events in high‑risk patients. Patients should be monitored for signs of abdominal pain, blood in stool, sudden weight gain, swelling, or rash, and seek medical attention promptly if these occur.

Ibuprofen should be avoided in individuals with known hypersensitivity to ibuprofen or other NSAIDs, active gastrointestinal ulcer disease, severe heart failure, third‑trimester pregnancy, and in patients with significant renal or hepatic impairment unless directed by a physician. Consultation with a healthcare professional is essential before starting therapy.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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