Product image of Ibuprofen Farmalider (Ibuprofen) supplied by GNH India

Ibuprofen Farmalider

Active Ingredient:
Ibuprofen
Origin:
EU

Ibuprofen Farmalider (Ibuprofen)

Ibuprofen, the active ingredient in Ibuprofen Farmalider, is a nonsteroidal anti‑inflammatory drug (NSAID) presented as an oral dosage form for oral use. It is indicated for mild to moderate pain, fever and inflammation in adults and, where appropriate, children.
GNH India supplies Ibuprofen Farmalider as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Farmalider, S.A.

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Indications & Clinical Uses

Ibuprofen acts systemically to reduce pain, fever and inflammatory processes.

  • Mild to moderate pain: provides analgesia by lowering pain‑signal transmission.
  • Fever: lowers elevated body temperature through central thermoregulatory effects.
  • Inflammation: diminishes swelling and redness by inhibiting prostaglandin‑mediated pathways.

How It Works

  • Ibuprofen exerts its effect by reversibly inhibiting cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes, which reduces the synthesis of prostaglandins and thromboxanes. This decrease in prostaglandin production leads to lowered inflammation, pain perception, and fever generation.

Side Effects

Adverse reactions may occur with ibuprofen use and vary in frequency.

Common Side Effects

  • Gastrointestinal upset: nausea, dyspepsia, or abdominal discomfort.
  • Headache or dizziness.
  • Mild skin rash or itching.
  • Elevated blood pressure in some individuals.

Serious or Rare Side Effects

  • Gastrointestinal bleeding or ulceration.
  • Acute renal impairment or worsening of chronic kidney disease.
  • Severe allergic reactions such as anaphylaxis or angioedema.
  • Hepatic enzyme elevation or liver injury.
  • Thrombotic cardiovascular events, especially with high‑dose or prolonged use.

Precautions & Warnings

Before initiating therapy, consider the following safety measures.

  • Assess gastrointestinal risk: avoid in patients with active ulcers or a history of GI bleeding.
  • Monitor renal function: use caution in those with impaired kidney function or dehydration.
  • Use the lowest effective dose for the shortest duration needed.
  • Avoid use in the third trimester of pregnancy and discuss risks with a healthcare professional.
  • Caution when combined with anticoagulants or other NSAIDs due to increased bleeding risk.
  • Store at room temperature: keep in the original pack, protect from moisture and direct sunlight.

Avoid Interactions

Ibuprofen can interact with several medication classes; awareness helps prevent adverse outcomes.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of serious bleeding.
  • Other NSAIDs or aspirin: additive gastrointestinal toxicity.
  • ACE inhibitors or diuretics: may reduce renal perfusion and function.

Moderate Interactions (Monitor Closely)

  • Selective serotonin reuptake inhibitors (SSRIs): heightened bleeding tendency.
  • Corticosteroids: synergistic risk of ulceration.
  • Methotrexate: reduced clearance leading to toxicity.
  • Lithium: possible increase in lithium levels.

Frequently Asked Questions

Ibuprofen Farmalider is used to relieve mild to moderate pain, reduce fever, and lessen inflammation associated with conditions such as musculoskeletal aches, dental pain, headache, and febrile illnesses. It provides symptomatic relief by targeting the underlying prostaglandin pathways that mediate these symptoms.

Ibuprofen works by reversibly blocking the cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes. This inhibition reduces the formation of prostaglandins, which are lipid compounds that promote inflammation, pain, and fever. Lower prostaglandin levels result in decreased swelling, pain perception, and body temperature.

The appropriate dose of ibuprofen is determined by the prescribing healthcare professional based on the patient’s age, weight, clinical condition, and response to therapy. Typical adult regimens range from 200 mg to 800 mg per dose, taken every 6‑8 hours, but exact dosing must follow the prescriber’s instructions.

Ibuprofen should be avoided in the third trimester of pregnancy because it may affect fetal cardiovascular development. Use during the first two trimesters requires careful risk‑benefit assessment by a clinician. While limited data suggest low transfer into breast milk, nursing mothers should consult a healthcare provider before use.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.

Compared with acetaminophen, ibuprofen provides both analgesic and anti‑inflammatory effects, whereas acetaminophen mainly reduces pain and fever without significant anti‑inflammatory activity. Compared with other NSAIDs such as naproxen, ibuprofen has a shorter half‑life, allowing more flexible dosing but may require more frequent administration for sustained relief.

Store the product at room temperature, preferably below 25 °C, in its original packaging to protect it from moisture and direct sunlight. Keep the container tightly closed and out of reach of children. Do not use the medication after the expiration date printed on the label.

Ibuprofen Farmalider is taken orally, usually with a full glass of water. It can be taken with or without food; however, taking it with meals or a snack may reduce the likelihood of gastrointestinal discomfort. Swallow tablets whole; do not crush or chew unless the formulation specifically permits it.

Serious risks include gastrointestinal bleeding or ulceration, especially in patients with a history of GI disease; acute kidney injury, particularly in those with pre‑existing renal impairment or dehydration; severe allergic reactions such as anaphylaxis; and increased risk of cardiovascular events like heart attack or stroke with high‑dose or prolonged use.

Ibuprofen should be avoided by individuals with known hypersensitivity to ibuprofen or other NSAIDs, those with active gastrointestinal bleeding or ulcer disease, patients in the third trimester of pregnancy, and persons with severe renal or hepatic impairment unless specifically directed by a physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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