Ibuprofen Fresenius Kabi (Ibuprofen)

Ibuprofen blocks the activity of cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which are essential for converting arachidonic acid into prostaglandins. By reducing prostaglandin production, ibuprofen diminishes inflammation, lowers body temperature, and interrupts pain signaling pathways.

The specific dose and infusion rate are determined by the prescribing clinician based on the patient’s condition, weight, renal function, and other clinical factors. Healthcare professionals should follow institutional protocols and the product’s prescribing information.

The safety of intravenous ibuprofen in pregnancy has not been established, and it is generally avoided unless the potential benefit outweighs the risk. Limited data exist for breastfeeding; clinicians should consider alternative therapies when possible.

To place an order, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed) and import documentation.

Compared with oral NSAIDs, the intravenous form offers faster onset of action and is useful when patients cannot take oral medication. Its efficacy in pain and fever control is similar to other ibuprofen products, but the safety profile, especially gastrointestinal and renal risks, remains comparable to other systemic NSAIDs.

The product should be stored at 2‑8 °C, protected from light, and must not be frozen or shaken. Before administration, inspect the solution for particulate matter or discoloration and use aseptic technique as per hospital pharmacy standards.

Ibuprofen Fresenius Kabi is given by intravenous infusion. The infusion rate and total volume are set by the prescribing clinician, typically using a calibrated infusion pump. Administration should follow aseptic technique and institutional guidelines for IV drug delivery.

Serious adverse events include gastrointestinal bleeding or ulceration, acute renal failure, severe allergic reactions such as anaphylaxis, and rare skin disorders like Stevens‑Johnson syndrome. Patients should be monitored closely for signs of bleeding, renal dysfunction, or hypersensitivity.

Ibuprofen Fresenius Kabi is contraindicated in patients with known hypersensitivity to ibuprofen or other NSAIDs, active gastrointestinal ulceration, severe uncontrolled hypertension, advanced heart failure, and those with significant renal impairment. It should also be avoided in late‑term pregnancy unless absolutely necessary.