Product image of Ibuprofen Galpharm Healthcare Limited (Ibuprofen) supplied by GNH India

Ibuprofen Galpharm Healthcare Limited

Active Ingredient:
Ibuprofen
Origin:
EU

Ibuprofen Galpharm Healthcare Limited (Ibuprofen)

Ibuprofen, the active ingredient in Ibuprofen Galpharm Healthcare Limited, is a nonsteroidal anti‑inflammatory drug (NSAID) presented as an oral tablet for oral use. It relieves pain, reduces fever, and diminishes inflammation in adults and children when appropriate.

GNH India supplies Ibuprofen Galpharm Healthcare Limited as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The product complies with EU quality standards and is manufactured under GMP conditions.

Manufacturer / TM Owner

Galpharm Healthcare Limited

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Indications & Clinical Uses

Ibuprofen acts as an analgesic, antipyretic and anti‑inflammatory agent, providing relief across several common conditions.

  • Pain: Reduces mild to moderate pain such as headache, dental or musculoskeletal discomfort.
  • Fever: Lowers elevated body temperature associated with infections or inflammatory states.
  • Inflammation: Decreases swelling and stiffness in conditions like arthritis or soft‑tissue injury.

How It Works

  • Ibuprofen exerts its effect by non‑selectively inhibiting cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes. This inhibition blocks the conversion of arachidonic acid to prostaglandins, thereby decreasing the synthesis of mediators that promote pain, fever, and inflammation at the site of tissue injury.

Side Effects

Ibuprofen may cause a range of adverse reactions, which are generally categorized by frequency and severity.

Common Side Effects

  • Dyspepsia or stomach upset.
  • Nausea or mild vomiting.
  • Headache.
  • Dizziness.
  • Mild rash or itching.

Serious or Rare Side Effects

  • Gastrointestinal bleeding or ulceration.
  • Severe allergic reactions such as angioedema or anaphylaxis.
  • Renal impairment or acute kidney injury.

Precautions & Warnings

Before using ibuprofen, consider the following safety measures.

  • Cardiovascular risk: Use the lowest effective dose for the shortest duration to limit heart‑related events.
  • Gastrointestinal health: Avoid in patients with active ulcers or a history of serious GI bleeding.
  • Renal function: Monitor kidney function in individuals with pre‑existing renal disease.
  • Pregnancy and lactation: Consult a healthcare professional before use during pregnancy or breastfeeding.
  • Concomitant drugs: Review all current medications for potential interactions.
  • Store at ambient temperature: Keep below 25 °C, in the original packaging, protected from moisture and direct sunlight.

Avoid Interactions

Ibuprofen can interact with several medicines; awareness of the interaction level helps guide clinical decisions.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): Increased risk of serious bleeding.
  • High‑dose aspirin: Enhanced gastrointestinal toxicity.
  • Selective COX‑2 inhibitors: Additive cardiovascular risk.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: May reduce antihypertensive effect and affect renal function.
  • Diuretics: Potential for decreased renal perfusion.
  • Lithium: Ibuprofen can raise serum lithium levels.
  • Methotrexate: May increase methotrexate toxicity at high doses.

Frequently Asked Questions

Ibuprofen Galpharm Healthcare Limited is used to relieve mild to moderate pain, reduce fever, and lessen inflammation associated with conditions such as headaches, dental pain, musculoskeletal aches, and arthritic disorders. It is an NSAID that provides symptomatic relief in these common clinical situations.

Ibuprofen works by non‑selectively inhibiting the cyclooxygenase enzymes COX‑1 and COX‑2, which are essential for the production of prostaglandins. By reducing prostaglandin synthesis, ibuprofen lowers the inflammatory response, diminishes pain signals, and helps reset the body’s temperature set‑point, thereby reducing fever.

The appropriate dose of ibuprofen is determined by the prescribing healthcare professional based on the patient’s age, weight, clinical condition, and treatment goals. Dosage recommendations are individualized and should follow the prescriber’s instructions and any applicable product labeling.

Safety of ibuprofen in pregnancy and lactation depends on the trimester and individual risk factors. It is generally avoided in the third trimester due to potential fetal cardiovascular effects. Breastfeeding mothers should consult a healthcare provider, as small amounts may be excreted in milk. Professional guidance is essential before use.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, and will request verification of trade or institutional credentials. After confirmation, the team provides pricing, availability, shipping details (including any cold‑chain requirements), and assists with import documentation.

Ibuprofen shares the same COX‑inhibiting mechanism as other NSAIDs such as naproxen or diclofenac, but it has a relatively short half‑life and a well‑established safety profile at recommended doses. Compared with selective COX‑2 inhibitors, ibuprofen has a lower risk of cardiovascular events but a higher potential for gastrointestinal irritation.

Ibuprofen Galpharm Healthcare Limited should be stored at ambient temperature, preferably below 25 °C. Keep the tablets in the original container, protect them from moisture, heat, and direct sunlight, and ensure the packaging remains tightly closed until use.

Ibuprofen is administered orally, typically as a tablet that is swallowed whole with a full glass of water. It can be taken with or without food, although taking it with food may reduce the likelihood of stomach upset.

The most serious risks include gastrointestinal bleeding or ulceration, severe allergic reactions such as anaphylaxis, and renal impairment, especially in patients with pre‑existing kidney disease or those taking other nephrotoxic agents. Prompt medical attention is required if any of these serious events occur.

Individuals with a known hypersensitivity to ibuprofen or other NSAIDs, those with active gastrointestinal ulcers, severe heart failure, or significant renal impairment should avoid ibuprofen. Pregnant women in the third trimester and patients on anticoagulant therapy should also consult a healthcare professional before use.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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