Product image of Ibuprofen Hasco (Ibuprofen) supplied by GNH India

Ibuprofen Hasco

Active Ingredient:
Ibuprofen
Origin:
EU

Ibuprofen Hasco (Ibuprofen)

Ibuprofen, the active ingredient in Ibuprofen Hasco, is a Nonsteroidal anti-inflammatory drug (NSAID) presented as an oral tablet for systemic use. It treats mild to moderate pain, fever and inflammation in adults and children when appropriate.

GNH India supplies Ibuprofen Hasco as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Hasco-Lek

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Indications & Clinical Uses

Ibuprofen acts on the cyclo‑oxygenase pathway to reduce inflammation and pain.

  • Mild to moderate pain: provides analgesia for headaches, dental pain, musculoskeletal aches.
  • Fever: lowers elevated body temperature associated with infection or inflammation.
  • Osteoarthritis: alleviates joint pain and stiffness in chronic degenerative disease.
  • Rheumatoid arthritis: reduces inflammatory pain and swelling in autoimmune joint disease.
  • General inflammation: diminishes swelling and discomfort in soft‑tissue injuries.

How It Works

  • Ibuprofen non‑selectively inhibits cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, decreasing the conversion of arachidonic acid to prostaglandins. Reduced prostaglandin synthesis leads to diminished inflammation, lower pain signalling, and decreased fever response throughout the body.

Side Effects

Adverse reactions may vary in frequency and severity.

Common Side Effects

  • Gastrointestinal discomfort or dyspepsia
  • Nausea or vomiting
  • Headache
  • Dizziness
  • Mild skin rash
  • Transient elevation of liver enzymes

Serious or Rare Side Effects

  • Gastrointestinal ulceration or bleeding
  • Acute renal impairment or failure
  • Severe allergic reactions including anaphylaxis
  • Hepatotoxicity with marked enzyme rise
  • Cardiovascular thrombotic events (e.g., myocardial infarction)
  • Stevens‑Johnson syndrome or toxic epidermal necrolysis

Precautions & Warnings

Before using Ibuprofen, consider the following safety measures.

  • Renal function assessment: avoid use in severe kidney disease.
  • Gastrointestinal risk: use lowest effective dose in patients with ulcer history.
  • Cardiovascular caution: limit use in patients with established heart disease.
  • Hypersensitivity: discontinue if rash or swelling develops.
  • Concomitant anticoagulants: monitor bleeding risk closely.
  • Store at room temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Ibuprofen can affect the activity of several other medicines.

Major Interactions (Avoid)

  • Warfarin or other anticoagulants: increased bleeding risk.
  • Lithium: elevated serum lithium levels.
  • Methotrexate: reduced clearance leading to toxicity.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: possible reduction in renal function.
  • Diuretics: enhanced risk of renal impairment.
  • Selective serotonin reuptake inhibitors (SSRIs): additive bleeding tendency.

Frequently Asked Questions

Ibuprofen Hasco is indicated for the relief of mild to moderate pain, reduction of fever, and management of inflammation associated with conditions such as osteoarthritis, rheumatoid arthritis, and acute musculoskeletal injuries. It is an over‑the‑counter NSAID commonly used in adults and, when appropriate, in children.

Ibuprofen works by non‑selectively blocking the cyclo‑oxygenase‑1 and cyclo‑oxygenase‑2 enzymes, which are essential for the production of prostaglandins. Lower prostaglandin levels reduce inflammation, diminish pain‑signal transmission, and reset the hypothalamic set‑point that controls body temperature, thereby lowering fever.

The appropriate dose of Ibuprofen Hasco is determined by the prescribing healthcare professional based on the individual’s age, weight, clinical condition, and response to therapy. Patients should follow the prescriber’s instructions and the product labeling, and should not exceed the recommended maximum daily amount.

Safety of ibuprofen during pregnancy and lactation depends on the trimester and clinical circumstances. Generally, ibuprofen is avoided in the third trimester because of potential fetal cardiovascular effects, and caution is advised throughout pregnancy. While small amounts are excreted in breast milk, use should be discussed with a healthcare provider to weigh benefits against risks.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity of Ibuprofen Hasco. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Ibuprofen shares a similar mechanism of action with other non‑selective NSAIDs such as naproxen and diclofenac, but it is often preferred for its relatively short half‑life, which allows flexible dosing and quicker clearance. Compared with selective COX‑2 inhibitors, ibuprofen may have a higher gastrointestinal risk but a lower cardiovascular risk profile.

Ibuprofen Hasco should be stored at room temperature, below 25 °C, in its original packaging to protect it from moisture and light. Keep the product out of reach of children and avoid storing it in humid environments such as bathrooms.

Ibuprofen Hasco is taken orally, usually with a full glass of water. It can be taken with or without food, although taking it with food or milk may reduce gastrointestinal discomfort. The tablet should be swallowed whole and not chewed or crushed unless specifically instructed by a healthcare professional.

Serious risks include gastrointestinal bleeding or ulceration, acute kidney injury, severe allergic reactions such as anaphylaxis, and increased risk of cardiovascular events like heart attack or stroke, especially with high‑dose or prolonged use. Patients should seek immediate medical attention if they notice signs of bleeding, severe rash, or chest pain.

Individuals with known hypersensitivity to ibuprofen or other NSAIDs, those with active gastrointestinal ulcers, severe renal or hepatic impairment, uncontrolled hypertension, or a history of cardiovascular thrombotic events should avoid ibuprofen. It is also contraindicated in late pregnancy and should be used with caution in patients on anticoagulant therapy.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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