Product image of Ibuprofen Hermes (Ibuprofen) supplied by GNH India

Ibuprofen Hermes

Active Ingredient:
Ibuprofen
Origin:
EU

Ibuprofen Hermes (Ibuprofen)

Ibuprofen, the active ingredient in Ibuprofen Hermes, is a Nonsteroidal anti-inflammatory drug (NSAID) presented as a topical formulation for skin application. It is used to relieve mild to moderate pain, reduce inflammation in musculoskeletal conditions, and treat localized skin inflammation.

GNH India supplies Ibuprofen Hermes as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to EU GMP standards, offers batch release certificates, and supports import requirements for diverse markets.

Manufacturer / TM Owner

Hermes Arzneimittel Gmbh

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Indications & Clinical Uses

Ibuprofen is an NSAID that reduces inflammation and pain by inhibiting cyclooxygenase enzymes.

  • Mild to moderate pain: provides analgesic relief for headaches, dental pain, and minor injuries.
  • Musculoskeletal inflammation: decreases swelling and discomfort in conditions such as sprains, strains, and arthritis.
  • Localized skin inflammation: alleviates redness and irritation associated with minor dermatologic irritations.

How It Works

  • Ibuprofen reversibly inhibits both cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes, which catalyze the conversion of arachidonic acid to prostaglandins. By lowering prostaglandin synthesis, it reduces peripheral sensitisation of nociceptors, diminishes inflammatory exudate, and lowers fever. The topical delivery allows localized enzyme inhibition at the site of application, limiting systemic exposure.

Side Effects

Topical ibuprofen may cause local and systemic adverse reactions, most of which are mild.

Common Side Effects

  • Skin irritation: redness, itching, or burning at the application site.
  • Dryness: mild peeling or flaking of the skin.
  • Pruritus: localized itching.

Serious or Rare Side Effects

  • Allergic dermatitis: widespread rash, swelling, or hives.
  • Systemic NSAID effects: gastrointestinal bleeding or ulceration.
  • Renal impairment: decreased kidney function with prolonged use.
  • Cardiovascular events: increased risk of heart attack or stroke in susceptible individuals.

Precautions & Warnings

When using topical ibuprofen, consider the following precautions.

  • Assess skin integrity: avoid application on broken, infected, or severely inflamed skin.
  • Limit exposure: use the smallest amount needed for symptom relief.
  • Monitor for systemic absorption: watch for signs of gastrointestinal upset or renal changes, especially in elderly patients.
  • Contraindications: do not use in individuals with known hypersensitivity to ibuprofen or other NSAIDs.
  • Drug interactions: consult a healthcare provider if taking anticoagulants, antihypertensives, or other NSAIDs.
  • Store at room temperature: keep in the original container, protect from light and moisture.

Avoid Interactions

Ibuprofen can interact with several medicines; awareness helps minimise risk.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of bleeding.
  • Other NSAIDs or COX‑2 inhibitors: additive gastrointestinal toxicity.
  • Corticosteroids: heightened risk of ulceration.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: possible reduction in renal function.
  • Diuretics: potential for decreased kidney perfusion.
  • Lithium: increased lithium serum levels.
  • Methotrexate: reduced clearance leading to toxicity.

Frequently Asked Questions

Ibuprofen Hermes is a topical NSAID formulation designed to relieve mild to moderate pain, reduce inflammation in musculoskeletal conditions, and treat localized skin inflammation such as irritations or minor dermatitis.

Ibuprofen works by reversibly inhibiting the cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which reduces the synthesis of prostaglandins. Lower prostaglandin levels diminish pain signalling, inflammation, and fever at the site where the product is applied.

The appropriate amount and frequency of application are determined by the prescribing healthcare professional based on the individual’s condition, age, and response. Patients should follow the prescriber’s instructions and the product label.

Safety data for topical ibuprofen in pregnancy and lactation are limited. Women who are pregnant, planning pregnancy, or breastfeeding should discuss potential risks with their healthcare provider before using the product.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Compared with oral NSAIDs, the topical formulation of Ibuprofen Hermes delivers the active ingredient directly to the affected area, potentially reducing systemic exposure and associated gastrointestinal or cardiovascular risks. However, its efficacy is limited to superficial conditions, whereas oral NSAIDs treat deeper or systemic pain.

Store the product at room temperature, preferably below 25 °C, in its original container. Protect it from direct sunlight, excessive moisture, and heat sources to maintain stability and potency.

Apply a thin layer of the cream or gel to clean, dry skin over the painful or inflamed area. Gently rub until fully absorbed, and wash hands after use to avoid accidental contact with eyes or mucous membranes.

Serious risks, though rare, include systemic NSAID effects such as gastrointestinal bleeding, ulceration, renal impairment, and cardiovascular events like heart attack or stroke. Allergic reactions such as widespread rash, swelling, or anaphylaxis also require immediate medical attention.

Individuals with a known hypersensitivity to ibuprofen, other NSAIDs, or any component of the formulation should avoid use. It is also contraindicated on broken, infected, or severely inflamed skin, and caution is advised for patients with severe renal, hepatic, or cardiovascular disease.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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