Product image of Ibuprofen Ibudolor (Ibuprofen) supplied by GNH India

Ibuprofen Ibudolor

Active Ingredient:
Ibuprofen
Origin:
EU

Ibuprofen Ibudolor (Ibuprofen)

Ibuprofen, the active ingredient in Ibuprofen Ibudolor, is a non‑steroidal anti‑inflammatory drug (NSAID) presented as an oral dosage form for oral use. It is used to relieve mild to moderate pain, reduce fever, and manage inflammatory conditions such as arthritis in adult patients.

GNH India supplies Ibuprofen Ibudolor as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides reliable global distribution, including regulatory documentation and temperature‑controlled logistics where required.

Manufacturer / TM Owner

Stada D.O.O.

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Indications & Clinical Uses

  • Ibuprofen acts as an analgesic and antipyretic by inhibiting cyclooxygenase enzymes involved in prostaglandin synthesis.
  • Mild to moderate pain: provides analgesic relief in conditions such as headache, dental pain, and musculoskeletal discomfort.
  • Fever: lowers elevated body temperature in febrile states.
  • Arthritis (inflammatory joint conditions): reduces inflammation and pain associated with osteoarthritis and rheumatoid arthritis.

How It Works

  • Ibuprofen exerts its effect through non‑selective inhibition of cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes, decreasing the conversion of arachidonic acid to prostaglandins and thromboxanes. The reduction of prostaglandin synthesis diminishes peripheral sensitization of nociceptors, lowers the hypothalamic set‑point for temperature, and attenuates inflammatory mediators in affected tissues.

Side Effects

Ibuprofen may cause a range of adverse reactions, varying from mild to serious.

Common Side Effects

  • Gastro‑intestinal discomfort (e.g., dyspepsia, nausea)
  • Headache
  • Dizziness or light‑headedness
  • Mild skin rash

Serious or Rare Side Effects

  • Gastro‑intestinal bleeding or ulcer perforation
  • Severe allergic reactions (e.g., anaphylaxis, Stevens‑Johnson syndrome)
  • Renal impairment or acute kidney injury
  • Elevated liver enzymes or hepatitis

Precautions & Warnings

  • When using ibuprofen, consider the following precautions to minimize risk.
  • Assess gastrointestinal risk: evaluate history of ulcers, bleeding disorders, or chronic NSAID use.
  • Monitor renal function: especially in elderly, dehydrated, or patients with pre‑existing kidney disease.
  • Avoid in known hypersensitivity: discontinue if allergic reactions to ibuprofen or other NSAIDs occur.
  • Use lowest effective dose: limit duration to the shortest period necessary for symptom control.
  • Store at ambient temperature: keep in the original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Ibuprofen can interact with several medicines; awareness of major and moderate interactions helps ensure safe co‑administration.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of bleeding.
  • Concurrent use with other NSAIDs or COX‑2 inhibitors: additive gastrointestinal toxicity.
  • ACE inhibitors or ARBs in patients with renal impairment: heightened risk of renal failure.

Moderate Interactions (Monitor Closely)

  • Diuretics: may reduce renal perfusion and function.
  • Lithium: ibuprofen can raise lithium serum concentrations.
  • Corticosteroids: combined use raises the chance of gastrointestinal ulceration.

Frequently Asked Questions

Ibuprofen Ibudolor is an oral NSAID indicated for the relief of mild to moderate pain, reduction of fever, and management of inflammatory conditions such as osteoarthritis and rheumatoid arthritis. It is commonly prescribed for headaches, dental pain, musculoskeletal discomfort, and febrile episodes.

Ibuprofen works by non‑selectively inhibiting the cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which are key in the conversion of arachidonic acid to prostaglandins. By lowering prostaglandin levels, it reduces inflammation, diminishes pain signaling, and lowers the hypothalamic set‑point for body temperature.

The appropriate dose of Ibuprofen Ibudolor is determined by the prescribing healthcare professional based on the patient’s age, weight, clinical condition, and response to therapy. Dosage regimens may differ for pain, fever, or chronic inflammatory disorders, and should always follow the prescriber’s instructions.

Safety data for ibuprofen in pregnancy and lactation are limited. It is generally avoided in the third trimester because of potential fetal cardiovascular effects, and caution is advised throughout pregnancy. Breastfeeding mothers should consult a healthcare provider, as ibuprofen can be excreted in milk.

To order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any temperature‑controlled requirements), and necessary import documentation.

Ibuprofen Ibudolor belongs to the same class of non‑selective NSAIDs as naproxen, diclofenac, and aspirin. Its efficacy for pain, fever, and inflammation is comparable, while its safety profile reflects the typical NSAID risks of gastrointestinal irritation and renal effects. Choice among NSAIDs often depends on patient tolerance, dosing frequency, and specific clinical considerations.

Store Ibuprofen Ibudolor at ambient temperature, preferably below 25 °C. Keep the product in its original container, protect it from moisture, direct sunlight, and excessive heat. Ensure the packaging remains sealed until use to maintain product stability.

Ibuprofen Ibudolor is taken orally with a full glass of water. It may be taken with or without food; however, consuming it with meals can reduce the likelihood of gastrointestinal discomfort. Swallow tablets whole; do not crush or chew unless specifically instructed by a healthcare professional.

Serious risks include gastrointestinal bleeding or ulcer perforation, severe allergic reactions such as anaphylaxis or Stevens‑Johnson syndrome, acute kidney injury, and elevated liver enzymes indicating hepatic stress. Patients should seek immediate medical attention if they experience black stools, severe abdominal pain, rash, swelling, or sudden changes in urine output.

Ibuprofen Ibudolor should be avoided in individuals with known hypersensitivity to ibuprofen or other NSAIDs, those with active gastrointestinal ulcers or bleeding disorders, patients with severe renal or hepatic impairment, and anyone who has experienced a previous serious cardiovascular event linked to NSAID use. Consultation with a healthcare professional is essential before initiating therapy.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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