Product image of Ibuprofen supplied by GNH India

Ibuprofen

Active Ingredient:
Ibuprofen
Origin:
EU

Ibuprofen

Ibuprofen, the active ingredient in Ibuprofen, is a nonsteroidal anti-inflammatory drug presented as a strength/form for oral use. It treats pain, fever, inflammation and related conditions in adults and children as directed.

GNH India supplies Ibuprofen as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Ria Generics Limited

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Indications & Clinical Uses

  • Ibuprofen works by reducing inflammation and relieving pain across several common conditions.
  • Pain: Provides analgesic relief for mild to moderate pain.
  • Fever: Lowers elevated body temperature.
  • Inflammation: Decreases swelling in injured tissues.
  • Headache: Alleviates tension‑type and migraine‑associated headache.
  • Musculoskeletal pain: Reduces discomfort from strains, sprains and arthritis.
  • Menstrual pain: Eases dysmenorrhea associated cramping.

How It Works

  • Ibuprofen non‑selectively inhibits cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes, which blocks the conversion of arachidonic acid to prostaglandins. The resulting decrease in prostaglandin synthesis reduces inflammation, pain signaling, and fever generation at the site of tissue injury.

Side Effects

Common Side Effects

  • Gastrointestinal upset such as nausea, dyspepsia or heartburn.
  • Headache or dizziness.
  • Mild rash or itching.
  • Elevated blood pressure in some individuals.

Serious or Rare Side Effects

  • Gastrointestinal bleeding, ulceration or perforation.
  • Acute kidney injury or worsening of chronic renal disease.
  • Severe allergic reactions including anaphylaxis or Stevens‑Johnson syndrome.
  • Hepatotoxicity manifested by jaundice or abnormal liver enzymes.

Precautions & Warnings

  • Before using ibuprofen, consider the following safety measures.
  • Assess gastrointestinal risk: evaluate history of ulcers or bleeding.
  • Monitor renal function: avoid in patients with severe kidney impairment.
  • Check cardiovascular status: use cautiously in those with heart disease or hypertension.
  • Avoid use with other NSAIDs or aspirin: increases risk of adverse effects.
  • Store at ambient temperature: keep in the original packaging, protect from moisture and heat.

Avoid Interactions

Ibuprofen may interact with several medicines; awareness helps prevent complications.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): heightened bleeding risk.
  • Other NSAIDs or aspirin: additive gastrointestinal toxicity.
  • Lithium: increased lithium serum levels.
  • Methotrexate: reduced clearance leading to toxicity.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: possible reduction in renal function.
  • Diuretics: may exacerbate fluid loss and kidney injury.
  • SSRIs or SNRIs: increased bleeding tendency.
  • Antihypertensives: potential attenuation of blood‑pressure‑lowering effect.
  • Oral hypoglycemics: may affect glucose control.

Frequently Asked Questions

Ibuprofen is used to relieve mild to moderate pain, reduce fever, and decrease inflammation. It is commonly employed for headaches, toothaches, menstrual cramps, musculoskeletal aches, and arthritic discomfort, providing symptomatic relief in adults and children when directed by a healthcare professional.

Ibuprofen works by blocking the cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which are essential for producing prostaglandins. By lowering prostaglandin levels, it reduces the signals that cause pain, fever, and inflammation at the site of injury or illness.

The appropriate ibuprofen dose is determined by a prescriber based on the individual's age, weight, condition being treated, and overall health. Patients should follow the specific dosing instructions provided on the prescription label or by their healthcare provider.

Ibuprofen should be used with caution during pregnancy, especially in the third trimester, as it may affect fetal circulation. While short‑term use may be acceptable in early pregnancy, it is generally avoided later. Breastfeeding mothers should consult a healthcare professional before use.

To order ibuprofen, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, and will request trade or institutional credentials before providing pricing, availability, shipping details and any necessary import documentation.

Ibuprofen shares the same class mechanism as other NSAIDs such as naproxen and diclofenac, offering comparable analgesic and anti‑inflammatory effects. Differences lie in duration of action, dosing frequency, and individual tolerability; ibuprofen is often chosen for its relatively short half‑life and well‑established safety profile.

Ibuprofen should be stored at ambient temperature, ideally below 25 °C. Keep the product in its original container, protect it from moisture, direct sunlight and excessive heat to maintain potency throughout its shelf life.

Ibuprofen is taken orally, usually as a tablet, capsule or liquid formulation. It should be swallowed with a full glass of water, and can be taken with food or milk to lessen potential stomach irritation, unless otherwise directed by a healthcare professional.

Serious risks include gastrointestinal bleeding or ulceration, severe allergic reactions such as anaphylaxis, kidney injury, and increased cardiovascular events in high‑risk patients. Users should seek immediate medical attention if they experience symptoms like black stools, severe abdominal pain, swelling, or rash.

Individuals with a known allergy to ibuprofen or other NSAIDs, active gastrointestinal ulcers, severe heart failure, advanced kidney disease, or those taking anticoagulants without medical supervision should avoid ibuprofen unless specifically advised by a physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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