Product image of Ibuprofen (Ibuprofen Bp) supplied by GNH India

Ibuprofen

Active Ingredient:
Ibuprofen Bp
Origin:
EU

Ibuprofen (Ibuprofen Bp)

Ibuprofen, the active ingredient in Ibuprofen, is a nonsteroidal anti-inflammatory drug presented as an oral tablet for oral use. It relieves mild to moderate pain, reduces fever, and decreases inflammation in adults and, when appropriate, in pediatric patients under medical guidance through prescribed regimens.

GNH India supplies Ibuprofen as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, adhering to stringent quality standards and providing reliable global logistics. Our distribution network ensures timely delivery across Europe, Asia, Africa and the Americas.

Manufacturer / TM Owner

Chelonia Healthcare Limited

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Indications & Clinical Uses

Ibuprofen is an NSAID that reduces prostaglandin‑mediated inflammation and pain.

  • Mild to moderate pain: provides analgesic relief for headaches, dental pain, musculoskeletal discomfort.
  • Fever: lowers elevated body temperature associated with infections or inflammatory conditions.
  • Osteoarthritis: alleviates joint pain and improves mobility in degenerative joint disease.
  • Rheumatoid arthritis: reduces joint inflammation and stiffness in autoimmune arthritis.
  • Dysmenorrhea: eases menstrual cramps and associated pelvic pain.

How It Works

  • Ibuprofen exerts its effect by reversibly inhibiting the cyclooxygenase enzymes COX‑1 and COX‑2. This inhibition blocks the conversion of arachidonic acid to prostaglandins, thereby decreasing the synthesis of mediators that promote inflammation, pain, and fever.

Side Effects

Adverse reactions may vary in frequency and severity.

Common Side Effects

  • Gastrointestinal discomfort: nausea, dyspepsia, or stomach upset.
  • Headache: mild to moderate intensity.
  • Dizziness: transient sensation of light‑headedness.
  • Rash: mild skin irritation or erythema.

Serious or Rare Side Effects

  • Gastrointestinal bleeding or ulcer perforation.
  • Acute renal impairment or worsening of existing kidney disease.
  • Severe allergic reactions such as anaphylaxis or angioedema.

Precautions & Warnings

Use ibuprofen with careful consideration of individual health status.

  • Cardiovascular risk assessment: evaluate history of heart disease before use.
  • Renal function monitoring: avoid in patients with severe kidney impairment.
  • Dose minimisation: employ the lowest effective dose for the shortest duration.
  • Pregnancy caution: avoid in the third trimester and discuss use with a healthcare professional.
  • Gastro‑intestinal ulcer risk: consider gastro‑protective agents in high‑risk patients.
  • Store at room temperature: keep in the original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Ibuprofen may interact with other medicines, altering efficacy or safety.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of bleeding.
  • Other NSAIDs (e.g., aspirin, naproxen): additive gastrointestinal toxicity.
  • Corticosteroids (e.g., prednisone): heightened ulcer risk.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors (e.g., lisinopril): possible reduction in antihypertensive effect and renal function.
  • Selective serotonin reuptake inhibitors (e.g., sertraline): modest increase in bleeding tendency.

Frequently Asked Questions

Ibuprofen is used to relieve mild to moderate pain such as headaches, dental pain, and musculoskeletal aches; to lower fever associated with infections or inflammatory states; and to reduce inflammation in conditions like osteoarthritis, rheumatoid arthritis, and dysmenorrhea.

Ibuprofen works by reversibly blocking the cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which are essential for converting arachidonic acid into prostaglandins. By lowering prostaglandin production, it diminishes the signals that cause pain, fever, and inflammation.

The appropriate ibuprofen dose is determined by a prescriber based on the individual’s age, weight, medical condition, and response to therapy. Patients should follow the specific dosing instructions provided by their healthcare professional.

Ibuprofen should be avoided in the third trimester of pregnancy because of potential fetal risks. During earlier stages and while breastfeeding, use only if clearly indicated and prescribed by a qualified healthcare provider after weighing benefits against possible risks.

To order ibuprofen, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Compared with acetaminophen, ibuprofen adds anti‑inflammatory activity, making it useful for conditions where swelling is present. Unlike stronger opioids, ibuprofen carries a lower risk of dependence but may have more gastrointestinal and renal considerations, especially at higher doses.

Ibuprofen tablets should be stored at room temperature, below 25 °C, in their original container. Keep them away from moisture, heat, and direct sunlight to maintain stability and potency throughout the shelf life.

Ibuprofen is taken orally, usually with a glass of water. It can be taken with food or milk to lessen stomach irritation, but it may also be taken on an empty stomach if tolerated. The exact administration schedule is set by the prescribing clinician.

Serious risks include gastrointestinal bleeding or ulcer perforation, acute kidney injury, and severe allergic reactions such as anaphylaxis. Patients with a history of cardiovascular disease, renal impairment, or ulcer disease should discuss these risks with their doctor before using ibuprofen.

Individuals with known hypersensitivity to ibuprofen or other NSAIDs, those with active gastrointestinal ulcers, severe heart failure, advanced kidney disease, or who are in the third trimester of pregnancy should avoid ibuprofen unless specifically directed by a healthcare professional.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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