Product image of Ibuprofen (Ibuprofen) 200 mg/1 Tablet supplied by GNH India

Ibuprofen (Ibuprofen)

Active Ingredient:
Ibuprofen (Ibuprofen)
Form:
Tablet
Brand:
IBUPROFEN
Origin:
US

Ibuprofen (Ibuprofen) (Tablet) 200 mg/1

Ibuprofen, the active ingredient in IBUPROFEN, is a nonsteroidal anti-inflammatory drug (NSAID) presented as a 200 mg/tablet for oral use. It is used to relieve pain, reduce fever, and decrease inflammation in adults and children 12 years and older.

GNH India supplies IBUPROFEN as a licensed, GDP-compliant international pharmaceutical supplier serving pharmacies and clinics worldwide.

Strength

200 mg/1

Manufacturer / TM Owner

H E B

1
Pack/s
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Indications & Clinical Uses

IBUPROFEN is used to manage pain and inflammation through its action on the prostaglandin pathway. It is indicated for:

  • Mild to moderate pain: headache, dental pain, menstrual cramps, muscle aches, or arthritis. Reduces pain and inflammation in these conditions.
  • Fever: Reduces fever in adults and children.
  • Inflammatory conditions: Symptomatic treatment of osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. Alleviates joint pain and stiffness.
  • Acute gout: Reduces pain and inflammation during gout attacks.
  • Musculoskeletal pain: Relieves minor aches and pains due to the common cold or flu.

How It Works

  • IBUPROFEN works by reversibly inhibiting cyclooxygenase (COX-1 and COX-2) enzymes, which are involved in the production of prostaglandins. By blocking these enzymes, it reduces the synthesis of prostaglandins, thereby decreasing inflammation, pain, and fever. This mechanism targets the sites of inflammation and pain, providing relief from various conditions.

Side Effects

IBUPROFEN may cause various side effects, ranging from common to serious. Common Side Effects:

  • Dyspepsia: Stomach upset or indigestion.
  • Nausea: Feeling sick to the stomach.
  • Diarrhea: Loose or watery stools.
  • Headache: Pain in the head.
  • Dizziness: Feeling lightheaded or unsteady.
  • Abdominal pain: Discomfort or pain in the stomach area.
  • Vomiting: Expelling stomach contents through the mouth.
  • Rash: Skin irritation or redness.

Serious or Rare Side Effects

  • Gastric ulcer: Open sores in the stomach lining.
  • GI bleeding: Bleeding in the gastrointestinal tract.
  • Bronchospasm: Constriction of the airways, leading to breathing difficulties.
  • Tinnitus: Ringing or buzzing in the ears.
  • Visual disturbances: Changes in vision.
  • Oedema: Swelling due to fluid retention.
  • Hypertension: High blood pressure.

Precautions & Warnings

IBUPROFEN should be used with caution and under the guidance of a healthcare professional. Important precautions include:

  • Allergy alert: Avoid if allergic to ibuprofen or any NSAID. May cause severe allergic reactions.
  • Stomach bleeding: Use with caution, as it may cause severe stomach bleeding.
  • Heart attack and stroke: Increased risk with long-term use. Monitor closely.
  • Renal impairment: Avoid in severe renal impairment (eGFR < 30 ml/min). Use with caution in moderate impairment.
  • Pregnancy: Avoid in the third trimester. Consult a doctor before use.
  • Children: Ask a doctor before use in children under 12 years.
  • Store at room temperature: Keep away from light and moisture. Store in a cool, dry place.

Avoid Interactions

IBUPROFEN may interact with other medications, potentially affecting their efficacy or increasing the risk of side effects. Major Interactions (Avoid):

  • Aspirin: Avoid concurrent use, as it may reduce the antiplatelet effect of aspirin.
  • Anticoagulants: Increased risk of bleeding. Avoid concurrent use.
  • ACE inhibitors: May reduce the blood pressure-lowering effect. Monitor closely.
  • Diuretics: May reduce the diuretic effect. Monitor closely.

Moderate Interactions (Monitor Closely)

  • Other NSAIDs: Increased risk of side effects. Monitor closely.
  • Corticosteroids: Increased risk of GI bleeding. Monitor closely.
  • Lithium: May increase lithium levels. Monitor lithium levels closely.
  • Methotrexate: May increase methotrexate levels. Monitor closely.

Frequently Asked Questions

IBUPROFEN is used to relieve mild to moderate pain, reduce fever, and decrease inflammation. It is commonly used for conditions such as headache, dental pain, menstrual cramps, muscle aches, arthritis, and the common cold. It is also used to treat inflammatory conditions like osteoarthritis, rheumatoid arthritis, and acute gout.

IBUPROFEN works by inhibiting the cyclooxygenase (COX-1 and COX-2) enzymes, which are involved in the production of prostaglandins. By blocking these enzymes, it reduces the synthesis of prostaglandins, thereby decreasing inflammation, pain, and fever. This mechanism targets the sites of inflammation and pain, providing relief from various conditions.

The usual dosage of IBUPROFEN is determined by a healthcare professional based on the condition being treated. For pain and fever, adults and children 12 years and older typically take 200-400 mg every 4-6 hours, not exceeding 1200 mg per day. For inflammatory conditions, the dosage may be higher, up to 3200 mg per day, as prescribed by a doctor.

IBUPROFEN should be avoided in the third trimester of pregnancy due to the risk of premature closure of the ductus arteriosus. It is generally not recommended during breastfeeding unless directed by a healthcare professional. Always consult a doctor before using IBUPROFEN during pregnancy or breastfeeding.

To order IBUPROFEN from GNH India, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams across international markets. The team will ask you to confirm your trade or institutional credentials and will reply with pricing, availability, shipping, and the necessary import paperwork.

IBUPROFEN is a nonsteroidal anti-inflammatory drug (NSAID) that is effective for pain relief, fever reduction, and inflammation. Compared to acetaminophen, which is also used for pain and fever but does not have anti-inflammatory properties, IBUPROFEN is often preferred for conditions involving inflammation. However, it may have a higher risk of side effects such as stomach bleeding and kidney issues.

IBUPROFEN should be stored at room temperature, away from light and moisture. Keep it in a cool, dry place and ensure the original packaging is properly sealed. Do not store in the bathroom or any area with high humidity. Always keep medications out of reach of children and pets.

IBUPROFEN is administered orally, usually with a full glass of water. It can be taken with or without food. If stomach upset occurs, it is recommended to take it with food, milk, or an antacid. Do not lie down for at least 10 minutes after taking the medication to avoid irritation of the esophagus.

The most serious risks associated with IBUPROFEN include severe stomach bleeding, heart attack, stroke, and severe allergic reactions. It is important to monitor for signs of stomach bleeding such as black, tarry stools or vomiting blood, and to seek immediate medical attention if any severe side effects occur. Regular monitoring is advised for long-term use.

IBUPROFEN should not be used by individuals who are allergic to ibuprofen or any NSAID, those with a history of asthma, nasal polyps, or allergic reactions to aspirin, and those with active peptic ulcer disease or gastrointestinal bleeding. It is also contraindicated in severe hepatic impairment, severe renal impairment, and severe heart failure. Always consult a healthcare professional before using IBUPROFEN.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

References

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