Product image of Ibuprofen Innfarm (Ibuprofen Lysine) supplied by GNH India

Ibuprofen Innfarm

Active Ingredient:
Ibuprofen Lysine
Origin:
EU

Ibuprofen Innfarm (Ibuprofen Lysine)

Ibuprofen, the active ingredient in Ibuprofen Innfarm, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an oral tablet for oral use. It is used to relieve mild to moderate pain, reduce fever, and alleviate inflammation in adults and children when appropriate.

GNH India supplies Ibuprofen Innfarm as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to European Union quality standards and provides reliable sourcing for healthcare providers across multiple regions.

Manufacturer / TM Owner

Inn-Farm D.O.O.

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Indications & Clinical Uses

Ibuprofen acts by inhibiting cyclo‑oxygenase enzymes, providing analgesic, antipyretic and anti‑inflammatory effects.

  • Pain: Reduces mild to moderate acute pain such as headache, dental pain, or musculoskeletal discomfort.
  • Fever: Lowers elevated body temperature associated with infections or inflammatory conditions.
  • Inflammation: Decreases swelling and stiffness in conditions like arthritis or soft‑tissue injuries.

How It Works

  • Ibuprofen lysine is a salt form of ibuprofen that is rapidly absorbed after oral administration. It reversibly inhibits both cyclo‑oxygenase‑1 (COX‑1) and cyclo‑oxygenase‑2 (COX‑2) enzymes, decreasing the conversion of arachidonic acid to prostaglandins. The reduction in prostaglandin synthesis diminishes peripheral sensitization of nociceptors, lowers the hypothalamic set‑point for temperature, and limits inflammatory mediator release, resulting in analgesic, antipyretic and anti‑inflammatory actions.

Side Effects

Like other NSAIDs, ibuprofen may cause a range of adverse reactions, varying from mild to serious.

Common Side Effects

  • Gastrointestinal discomfort: nausea, dyspepsia or abdominal pain.
  • Headache: mild to moderate intensity.
  • Dizziness or vertigo.
  • Rash or mild skin irritation.
  • Elevated blood pressure.

Serious or Rare Side Effects

  • Gastrointestinal ulceration or bleeding.
  • Severe hepatic injury.
  • Acute kidney injury or renal failure.
  • Anaphylactic or severe allergic reactions.
  • Cardiovascular events such as myocardial infarction or stroke.

Precautions & Warnings

When prescribing ibuprofen, consider the following precautions to minimize risk.

  • Assess renal function: avoid use in severe renal impairment.
  • Monitor hepatic status: use cautiously in liver disease.
  • Evaluate cardiovascular risk: limit use in patients with established heart disease.
  • Avoid in patients with active peptic ulcer disease or history of gastrointestinal bleeding.
  • Use the lowest effective dose for the shortest duration needed.
  • Store at ambient temperature: keep in the original container, protect from moisture and heat.

Avoid Interactions

Ibuprofen can interact with several medicines, altering efficacy or safety.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased bleeding risk.
  • Selective COX‑2 inhibitors: additive gastrointestinal toxicity.
  • High‑dose aspirin: enhanced renal impairment.
  • Lithium: increased serum lithium levels.
  • Methotrexate: reduced clearance leading to toxicity.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: possible reduction in antihypertensive effect and renal function.
  • Diuretics: risk of dehydration and renal impairment.
  • SSRIs or SNRIs: heightened bleeding tendency.
  • Cyclosporine: increased nephrotoxicity.
  • Beta‑blockers: may blunt antihypertensive response.

Frequently Asked Questions

Ibuprofen Innfarm is indicated for the relief of mild to moderate pain, reduction of fever, and mitigation of inflammation. It is commonly employed in conditions such as headache, dental pain, musculoskeletal aches, febrile illnesses, and inflammatory disorders like arthritis, when prescribed by a qualified healthcare professional.

Ibuprofen works by reversibly inhibiting the cyclo‑oxygenase enzymes COX‑1 and COX‑2, which are essential for converting arachidonic acid into prostaglandins. By lowering prostaglandin levels, it reduces pain signaling, lowers the hypothalamic set‑point for body temperature, and diminishes the inflammatory response.

The appropriate dose of ibuprofen is determined by the prescribing clinician based on the patient’s age, weight, clinical condition, and response to therapy. Dosage regimens may differ for pain, fever, or inflammatory indications, and the prescriber will tailor the amount and frequency to each individual case.

Safety data for ibuprofen in pregnancy and lactation are limited. It is generally avoided in the third trimester because of potential fetal cardiovascular effects, and caution is advised throughout pregnancy. Breastfeeding mothers should consult their healthcare provider, as ibuprofen does pass into breast milk in small amounts.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity of Ibuprofen Innfarm. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.

Ibuprofen and naproxen belong to the same NSAID class and share similar mechanisms of COX inhibition. Ibuprofen generally has a shorter half‑life, requiring more frequent dosing, while naproxen offers longer duration of action. Both carry comparable gastrointestinal and cardiovascular risks, but individual patient response and tolerability often guide the choice.

Ibuprofen Innfarm should be stored at ambient temperature, preferably below 25 °C. Keep the tablets in the original packaging, protect them from moisture, direct sunlight, and excessive heat to maintain potency throughout the shelf life.

Ibuprofen Innfarm is administered orally. The tablets are swallowed whole with a full glass of water, preferably after a meal or with food to lessen gastrointestinal irritation. The exact administration schedule is set by the prescribing clinician.

Serious risks include gastrointestinal bleeding or ulceration, severe liver injury, acute kidney failure, allergic reactions such as anaphylaxis, and cardiovascular events like heart attack or stroke. Patients should seek immediate medical attention if they experience symptoms such as black stools, severe abdominal pain, jaundice, sudden swelling, or chest discomfort.

Ibuprofen should be avoided in individuals with known hypersensitivity to ibuprofen or other NSAIDs, active peptic ulcer disease, severe renal or hepatic impairment, uncontrolled hypertension, and in the third trimester of pregnancy. It is also contraindicated in patients taking certain anticoagulants or other drugs that pose a high risk of serious interactions.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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