Product image of Ibuprofen Kruidvat (Ibuprofen) supplied by GNH India

Ibuprofen Kruidvat

Active Ingredient:
Ibuprofen
Origin:
EU

Ibuprofen Kruidvat (Ibuprofen)

Ibuprofen, the active ingredient in Ibuprofen Kruidvat, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an oral tablet for systemic use. It relieves pain, reduces fever, and diminishes inflammation in adults and children when appropriate.

GNH India supplies Ibuprofen Kruidvat as a licensed, GDP‑compliant international pharmaceutical supplier serving pharmacies and clinics worldwide.

Manufacturer / TM Owner

Mae Holding Bv

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Indications & Clinical Uses

  • Ibuprofen acts systemically to manage symptoms associated with inflammatory and febrile conditions.
  • Pain: Provides analgesic relief for mild to moderate musculoskeletal, dental, and headache pain.
  • Fever: Lowers elevated body temperature in febrile illnesses.
  • Inflammation: Reduces swelling and stiffness in conditions such as arthritis or minor injuries.

How It Works

  • Ibuprofen non‑selectively inhibits cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes, decreasing the conversion of arachidonic acid to prostaglandins. The reduced prostaglandin synthesis diminishes peripheral sensitisation of nociceptors, lowers the hypothalamic set‑point for temperature, and limits inflammatory exudate formation, resulting in analgesic, antipyretic, and anti‑inflammatory effects.

Side Effects

Adverse reactions may vary in frequency and severity.

Common Side Effects

  • Gastrointestinal discomfort such as dyspepsia or heartburn.
  • Nausea or mild vomiting.
  • Headache.
  • Dizziness.
  • Mild skin rash.

Serious or Rare Side Effects

  • Gastrointestinal ulceration or bleeding.
  • Renal impairment or acute kidney injury.
  • Severe hypersensitivity reactions, including anaphylaxis.
  • Hepatotoxicity.
  • Cardiovascular events such as myocardial infarction or stroke, especially with high‑dose or prolonged use.

Precautions & Warnings

  • Before using ibuprofen, consider the following safety measures.
  • Allergy assessment: Verify no known hypersensitivity to ibuprofen or other NSAIDs.
  • Cardiovascular risk: Use the lowest effective dose for the shortest duration in patients with heart disease.
  • Renal function: Monitor kidney function in individuals with pre‑existing renal impairment.
  • Gastrointestinal health: Caution in patients with a history of ulcers or bleeding disorders.
  • Pregnancy and lactation: Consult a healthcare professional before use during pregnancy or breastfeeding.
  • Store at ambient temperature: Keep below 25 °C, retain in original packaging, and protect from moisture.

Avoid Interactions

Ibuprofen may alter the activity of several other medicines.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of serious bleeding.
  • High‑dose aspirin: heightened gastrointestinal toxicity.
  • Selective COX‑2 inhibitors: additive renal and cardiovascular hazards.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: possible reduction in antihypertensive effect and renal function.
  • Diuretics: may diminish diuretic efficacy and increase nephrotoxicity.
  • Lithium: ibuprofen can raise serum lithium levels, requiring monitoring.

Frequently Asked Questions

Ibuprofen Kruidvat is an over‑the‑counter NSAID indicated for the temporary relief of mild to moderate pain, reduction of fever, and mitigation of inflammation associated with conditions such as headaches, dental pain, musculoskeletal aches, and minor arthritic discomfort.

Ibuprofen blocks the activity of cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which are essential for producing prostaglandins. By lowering prostaglandin levels, it reduces pain signaling, lowers the hypothalamic set‑point for temperature, and limits the inflammatory response.

The appropriate dose of Ibuprofen Kruidvat is determined by a qualified prescriber or pharmacist based on the individual's age, weight, clinical condition, and response to therapy. Patients should follow the specific instructions provided on the product label or by their healthcare professional.

Safety of ibuprofen in pregnancy and lactation is not fully established. It is generally advised to avoid ibuprofen during the third trimester and to consult a healthcare professional before use in any trimester or while breastfeeding to weigh potential risks and benefits.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Ibuprofen shares a similar mechanism of action with other non‑selective NSAIDs such as naproxen and diclofenac, but it generally has a shorter half‑life, which may allow for more flexible dosing. Its safety profile is comparable, though individual tolerability and specific risk factors (e.g., cardiovascular or gastrointestinal) influence drug choice.

Ibuprofen Kruidvat should be stored at ambient temperature, preferably below 25 °C. Keep the tablets in the original blister pack or container, protect them from moisture and direct sunlight, and keep out of reach of children.

The product is taken orally, usually with a full glass of water. It can be taken with or without food; however, taking it with food or milk may reduce the likelihood of gastrointestinal discomfort.

Serious risks include gastrointestinal bleeding or ulceration, severe allergic reactions such as anaphylaxis, renal impairment, and increased cardiovascular events (e.g., heart attack or stroke) especially with high‑dose or prolonged therapy. Patients should seek immediate medical attention if they experience symptoms such as severe abdominal pain, blood in stools, sudden swelling, or difficulty breathing.

Individuals with known hypersensitivity to ibuprofen or other NSAIDs, those with active gastrointestinal ulcers, severe heart failure, uncontrolled hypertension, or advanced renal disease should avoid using ibuprofen. It is also contraindicated in the third trimester of pregnancy and should be used with caution in the first two trimesters after medical advice.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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