Product image of Ibuprofen Kruidvat (Ibuprofen) supplied by GNH India

Ibuprofen Kruidvat

Active Ingredient:
Ibuprofen
Origin:
EU

Ibuprofen Kruidvat (Ibuprofen)

Ibuprofen, the active ingredient in Ibuprofen Kruidvat, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an oral tablet for oral use. It treats pain, fever, inflammation and arthritis in adults and adolescents when appropriate.
GNH India supplies Ibuprofen Kruidvat as a licensed, GDP‑compliant international pharmaceutical supplier serving pharmacies and clinics worldwide.

Manufacturer / TM Owner

Mae Holding Bv

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Indications & Clinical Uses

Ibuprofen acts systemically to relieve symptoms associated with inflammatory and painful conditions.

  • Pain: Reduces mild to moderate pain such as headache, dental pain, or musculoskeletal discomfort.
  • Fever: Lowers elevated body temperature in febrile states.
  • Inflammation: Decreases swelling and redness in conditions like sprains or minor injuries.
  • Arthritis: Alleviates joint pain and stiffness in osteoarthritis and rheumatoid arthritis.

How It Works

  • Ibuprofen inhibits the cyclooxygenase enzymes COX‑1 and COX‑2, which blocks the conversion of arachidonic acid to prostaglandins. By reducing prostaglandin synthesis, it diminishes inflammation, pain signaling, and fever generation at the site of tissue injury or infection.

Side Effects

Adverse reactions may occur with ibuprofen use.

Common Side Effects

  • Stomach upset or dyspepsia
  • Nausea or vomiting
  • Dizziness or light‑headedness
  • Headache
  • Mild skin rash
  • Heartburn

Serious or Rare Side Effects

  • Gastrointestinal bleeding or ulcer perforation
  • Severe allergic reactions (anaphylaxis, angioedema)
  • Liver injury (hepatitis, jaundice)
  • Kidney impairment or acute renal failure
  • Cardiovascular events (myocardial infarction, stroke)
  • Blood dyscrasias (e.g., thrombocytopenia)

Precautions & Warnings

Before using ibuprofen, consider the following safety measures.

  • Assess gastrointestinal risk: avoid if you have a history of ulcers or bleeding.
  • Monitor renal function: use cautiously in patients with kidney disease.
  • Check for hypersensitivity: discontinue if allergic reactions to ibuprofen or other NSAIDs occur.
  • Use the lowest effective dose: limit duration to reduce adverse‑event risk.
  • Pregnancy and breastfeeding: consult a healthcare professional before use.
  • Store at ambient temperature: keep in the original pack, protect from moisture.

Avoid Interactions

Ibuprofen can interact with several medicines; some combinations should be avoided while others require monitoring.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of bleeding.
  • Other NSAIDs or aspirin: additive gastrointestinal toxicity.
  • Selective serotonin reuptake inhibitors (SSRIs): heightened bleeding tendency.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: may affect kidney function when combined.
  • Diuretics: potential for reduced renal clearance and electrolyte disturbances.

Frequently Asked Questions

Ibuprofen Kruidvat is an over‑the‑counter NSAID indicated for the temporary relief of mild to moderate pain, reduction of fever, and mitigation of inflammation associated with conditions such as headaches, dental pain, musculoskeletal aches, and arthritis.

Ibuprofen blocks the cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which are essential for converting arachidonic acid into prostaglandins. By lowering prostaglandin levels, it reduces the signals that cause pain, fever, and inflammation.

The appropriate dose is determined by the prescribing healthcare professional based on the individual’s age, condition, and response. For OTC use, adults typically follow label instructions, but exact dosing should always be confirmed by a qualified prescriber.

The safety category for ibuprofen in pregnancy is not definitively established, and it is generally avoided in the third trimester. Breastfeeding mothers should consult a healthcare provider, as ibuprofen can pass into milk in small amounts.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Both ibuprofen and acetaminophen relieve pain and fever, but ibuprofen also has anti‑inflammatory properties due to COX inhibition. Acetaminophen lacks significant anti‑inflammatory effects and generally has a lower risk of gastrointestinal irritation, while ibuprofen may be more effective for swelling and joint pain.

Store the tablets at ambient temperature, preferably below 25 °C, in the original container to protect them from moisture and light. Keep out of reach of children and do not use if the packaging is damaged or the tablets appear discoloured.

Ibuprofen Kruidvat is taken orally with a full glass of water. It can be taken with or without food, although taking it with food may reduce stomach discomfort. Swallow the tablet whole; do not crush or chew unless specifically directed by a healthcare professional.

Serious risks include gastrointestinal bleeding or ulcer perforation, severe allergic reactions such as anaphylaxis, liver injury, acute kidney failure, and cardiovascular events like heart attack or stroke, especially with high‑dose or prolonged use.

Individuals with a known hypersensitivity to ibuprofen or other NSAIDs, those with active gastrointestinal ulcers, severe heart failure, uncontrolled hypertension, or advanced kidney disease should avoid ibuprofen. It is also contraindicated in late pregnancy without medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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