Product image of Ibuprofen Lysine Alkaloid-Int (Ibuprofen Lysine) supplied by GNH India

Ibuprofen Lysine Alkaloid-Int

Active Ingredient:
Ibuprofen Lysine
Origin:
EU

Ibuprofen Lysine Alkaloid-Int (Ibuprofen Lysine)

Ibuprofen lysine, the active ingredient in Ibuprofen Lysine Alkaloid-Int, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an oral formulation for systemic use. It is employed to relieve pain, reduce fever, and diminish inflammation in adult patients and in appropriate clinical situations, and is widely used in clinical practice.

GNH India supplies Ibuprofen Lysine Alkaloid-Int as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies, clinics and health‑care institutions worldwide, ensuring consistent quality, regulatory compliance and reliable logistics for global markets.

Manufacturer / TM Owner

Alkaloid-Int D.O.O.

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Indications & Clinical Uses

Ibuprofen lysine acts as an NSAID to alleviate symptoms associated with inflammatory pathways.

  • Pain: Provides analgesic relief by reducing prostaglandin‑mediated nociception.
  • Fever: Lowers elevated body temperature through central thermoregulatory effects.
  • Inflammation: Decreases swelling and redness by inhibiting prostaglandin synthesis in inflamed tissues.

How It Works

  • Ibuprofen lysine is rapidly absorbed after oral administration and is hydrolyzed to ibuprofen, which non‑selectively inhibits cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes. By blocking COX activity, the drug reduces the conversion of arachidonic acid to prostaglandins and thromboxanes, leading to decreased inflammation, pain signaling, and fever generation.

Side Effects

Adverse reactions to ibuprofen lysine can range from mild and frequent to severe but uncommon.

Common Side Effects

  • Gastrointestinal discomfort: nausea, dyspepsia or abdominal pain.
  • Headache: mild to moderate intensity.
  • Dizziness or vertigo.
  • Rash or mild skin irritation.

Serious or Rare Side Effects

  • Gastrointestinal bleeding or ulceration.
  • Severe renal impairment or acute kidney injury.
  • Anaphylactic or severe allergic reactions.
  • Hepatotoxicity: significant liver injury.

Precautions & Warnings

When using ibuprofen lysine, several precautions should be observed to minimize risk.

  • Assess gastrointestinal risk: evaluate history of ulcers or bleeding before initiating therapy.
  • Monitor renal function: check creatinine and urine output in patients with kidney disease.
  • Use the lowest effective dose: limit duration to the shortest period necessary.
  • Avoid in known hypersensitivity: discontinue if allergic reactions occur.
  • Concomitant use with anticoagulants: increase monitoring for bleeding.
  • Store at room temperature: keep in the original container, protect from moisture and heat.

Avoid Interactions

Ibuprofen lysine may interact with other medicines, requiring attention to avoid adverse outcomes.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin, DOACs): increased risk of bleeding.
  • Other NSAIDs or aspirin: additive gastrointestinal toxicity.
  • Corticosteroids: heightened risk of ulceration and bleeding.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: may reduce renal function when combined.
  • Diuretics: potential for decreased renal perfusion.
  • Lithium: ibuprofen can raise lithium serum levels.
  • Methotrexate: reduced clearance leading to toxicity.

Frequently Asked Questions

Ibuprofen Lysine Alkaloid-Int contains ibuprofen lysine, an NSAID that is used to relieve mild to moderate pain, reduce fever, and decrease inflammation associated with conditions such as musculoskeletal aches, dental pain, and febrile illnesses.

Ibuprofen lysine is converted in the body to ibuprofen, which non‑selectively blocks the cyclooxygenase‑1 and cyclooxygenase‑2 enzymes. This inhibition lowers prostaglandin production, thereby reducing pain signalling, fever generation, and inflammatory swelling.

The appropriate dose of ibuprofen lysine is determined by the prescribing healthcare professional based on the patient’s age, weight, clinical condition, and response to therapy. No fixed regimen is provided here; the prescriber sets the exact dosage.

Safety data for ibuprofen lysine in pregnancy and lactation are limited. It should only be used if the potential benefit justifies any possible risk to the fetus or infant, and this decision must be made by a qualified healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Ibuprofen lysine offers rapid absorption compared with standard ibuprofen tablets, potentially providing quicker onset of analgesia. Like other non‑selective NSAIDs, it shares similar efficacy for pain and fever but also carries comparable gastrointestinal, renal and cardiovascular risk profiles.

Store ibuprofen lysine at room temperature, preferably below 25 °C. Keep the product in its original packaging, protect it from moisture and direct heat, and ensure the container is tightly closed to maintain stability.

Ibuprofen lysine is administered orally. The tablets or capsules are swallowed whole with a glass of water, preferably with food or a full glass of liquid to reduce possible stomach irritation.

Serious risks include gastrointestinal bleeding or ulceration, severe kidney injury, anaphylactic allergic reactions, and significant liver toxicity. Patients should seek immediate medical attention if they notice blood in stools, sudden loss of kidney function, severe rash, or signs of an allergic reaction.

Ibuprofen lysine should be avoided in individuals with known hypersensitivity to ibuprofen or other NSAIDs, active gastrointestinal ulcer disease, severe heart failure, uncontrolled hypertension, or those taking anticoagulants without close medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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