Product image of Ibuprofen Lysine Sumarpharma (Ibuprofen D,l-Lysinate) supplied by GNH India

Ibuprofen Lysine Sumarpharma

Active Ingredient:
Ibuprofen D,l-Lysinate
Origin:
EU

Ibuprofen Lysine Sumarpharma (Ibuprofen D,l-Lysinate)

Ibuprofen lysine, the active ingredient in Ibuprofen Lysine Sumarpharma, is a nonsteroidal anti‑inflammatory drug presented as an oral tablet for oral use. It is indicated for the relief of mild to moderate pain, reduction of fever, and management of inflammatory conditions such as musculoskeletal pain, dysmenorrhea, and headache in adults.

GNH India supplies Ibuprofen Lysine Sumarpharma as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory documentation for global distribution.

Manufacturer / TM Owner

Alvogen Ehf

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Indications & Clinical Uses

Ibuprofen lysine is an NSAID that reduces prostaglandin‑mediated inflammation and is used for several common pain and fever states.

  • Mild to moderate pain: provides analgesic relief by decreasing peripheral pain signalling.
  • Fever: lowers elevated body temperature through central inhibition of prostaglandin synthesis.
  • Musculoskeletal inflammation: alleviates swelling and discomfort associated with joint and muscle injuries.
  • Dysmenorrhea: reduces menstrual cramps by diminishing uterine prostaglandin levels.
  • Headache: eases tension‑type and mild migraine headaches by attenuating vascular inflammation.

How It Works

  • Ibuprofen lysine exerts its effect by non‑selectively inhibiting cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes. This blockade reduces the conversion of arachidonic acid to prostaglandins and thromboxanes, leading to decreased inflammation, pain signalling, and fever generation. The lysine salt form enhances aqueous solubility, allowing faster absorption compared with standard ibuprofen.

Side Effects

Ibuprofen lysine may cause adverse reactions, ranging from mild to serious.

Common Side Effects

  • Nausea: mild stomach upset that may resolve with food.
  • Dyspepsia: indigestion or heartburn.
  • Headache: transient head discomfort.
  • Dizziness: light‑headed sensation.

Serious or Rare Side Effects

  • Gastrointestinal bleeding or ulceration: may present as black stools or abdominal pain.
  • Renal impairment: reduced kidney function, especially with prolonged use.
  • Severe allergic reaction: rash, swelling, or difficulty breathing indicating possible anaphylaxis.

Precautions & Warnings

When using ibuprofen lysine, certain precautions should be observed to minimize risk.

  • Assess renal function: monitor in patients with kidney disease.
  • Avoid in active peptic ulcer: increased risk of gastrointestinal bleeding.
  • Use cautiously in cardiovascular disease: may elevate blood pressure or thrombotic risk.
  • Limit alcohol consumption: enhances gastrointestinal irritation.
  • Pregnancy and breastfeeding: consult a healthcare professional before use.
  • Store at ambient temperature: keep in the original pack, protect from moisture.

Avoid Interactions

Ibuprofen lysine can interact with other medicines; awareness of major and moderate interactions helps ensure safe use.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased bleeding risk.
  • Other NSAIDs or aspirin: additive gastrointestinal toxicity.
  • Lithium: heightened lithium levels leading to toxicity.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: possible reduction in renal function.
  • SSRIs: modestly increased risk of bleeding.

Frequently Asked Questions

Ibuprofen Lysine Sumarpharma contains ibuprofen lysine, an NSAID indicated for the symptomatic relief of mild to moderate pain, reduction of fever, and treatment of inflammatory conditions such as musculoskeletal pain, dysmenorrhea, and tension‑type headaches. It is available over the counter in many EU markets and is intended for short‑term use in adults.

Ibuprofen lysine works by non‑selectively blocking the cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which are required for the synthesis of prostaglandins. By lowering prostaglandin levels, it reduces inflammation, diminishes pain signalling, and lowers elevated body temperature. The lysine salt improves water solubility, leading to faster absorption compared with standard ibuprofen.

The exact dose of Ibuprofen Lysine Sumarpharma is determined by the prescribing healthcare professional based on the individual’s age, weight, and clinical condition. In many over‑the‑counter settings, adult dosing commonly follows the label recommendations, but patients should always follow the specific instructions provided by their doctor or pharmacist.

Safety of ibuprofen lysine in pregnancy has not been definitively established, and it is generally advised to avoid use, especially in the third trimester, unless clearly indicated by a physician. During breastfeeding, small amounts may pass into milk; therefore, a healthcare professional should be consulted before use to weigh potential risks and benefits.

To order Ibuprofen Lysine Sumarpharma from GNH India, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements if applicable) and assistance with import documentation.

Ibuprofen lysine is comparable to standard ibuprofen tablets, but the lysine salt form offers higher aqueous solubility, which can result in faster onset of analgesic effect. Compared with other NSAIDs such as naproxen or diclofenac, its efficacy for pain and fever is similar, while its safety profile aligns with the class‑wide risks of gastrointestinal irritation and renal effects.

Ibuprofen Lysine Sumarpharma tablets should be stored at ambient temperature, preferably below 25 °C, in the original packaging to protect them from moisture and light. Keep the container tightly closed and out of reach of children. Do not store in bathrooms or near heat sources.

The product is administered orally. Swallow the tablet whole with a full glass of water, preferably with food or milk to reduce potential stomach irritation. Do not crush, chew, or split the tablet unless instructed by a healthcare professional.

The most serious risks associated with ibuprofen lysine include gastrointestinal bleeding or ulceration, severe renal impairment, and hypersensitivity reactions such as anaphylaxis. Patients should be alert for signs of black stools, sudden kidney dysfunction, swelling, rash, or breathing difficulties and seek immediate medical attention if these occur.

Ibuprofen Lysine Sumarpharma should be avoided in individuals with known hypersensitivity to ibuprofen or other NSAIDs, active peptic ulcer disease, severe heart failure, uncontrolled hypertension, or significant renal or hepatic impairment. It is also contraindicated in the third trimester of pregnancy and in patients receiving anticoagulant therapy without close medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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